Journals / Ege Klinikleri Tıp Dergisi / 2021 / Cilt: 59 - Sayı: 1

Evaluation of Troponin-I Interference in a Patient With Chest Pain

Göğüs Ağrısı Olan Olguda Troponin I İnterferansının Değerlendirilmesi

Pages
1–4
Publication Date
2022-10-11
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The result did not change when using a heterophile antibody blocking tube, but the same sample showed that the troponin T resultwas 3.69 ng/L.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Acute myocardial infarction (AMI) is the most common cause of morbidity and mortality in the world.
📊
Key Findings & Data:A 22-year-old woman was admitted to the emergency department with chest pain and palpitations.
💡
Conclusion & Impact:The result did not change when using a heterophile antibody blocking tube, but the same sample showed that the troponin T resultwas 3.69 ng/L.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Acute myocardial infarction (AMI) is the most common cause of morbidity and mortality in the world. Cardiac troponins play a key role in diagnosis, but some interferences may cause erroneously high results. A 22-year-old woman was admitted to the emergency department with chest pain and palpitations. Anangiography was performed after cardiac Troponin-I (cTnI) was 250 ng/L, but no vascular occlusion was observed. The cTnI value of the patient who was treated for myocarditis did not decrease despite the treatment. The sample of the patient was examined for interference. The result did not change when using a heterophile antibody blocking tube, but the same sample showed that the troponin T resultwas 3.69 ng/L.

Özet

Akut miyokardinfarktüsü (AMI) dünyada morbidite ve mortalitenin en sık nedenidir. Kardiyak troponinler tanıda anahtar rol oynar ancak bazı interferanslar hatalı yüksek sonuçlara neden olabilir. 22 yaşında göğüs ağrısı ve çarpıntı şikayeti ile acile başvuran kadın hasta, kardiyak Troponin-I (cTnI) değerinin 250 ng/L gelmesi üzerine anjiyografi yapıldı ancak bir damar oklüzyonuna rastlanmadı. Miyokardit tedavisi düzenlenen hastanın cTnI değeri tedaviye rağmen düşmedi. Hastanın numunesi interferans yönünden incelendi. Heterofil antikor blokan tüp(HBT) kullanıldığında sonucu değişmedi ancak aynı numunede troponin T sonucunun 3,69 ng/L olduğu görüldü.

🔖

Cite This Article

YAMAN, H., YAVUZ, H. B., YAMAN, S. K., KANT, S. (2022). Evaluation of Troponin-I Interference in a Patient With Chest Pain. Ege Klinikleri Tıp Dergisi, Cilt: 59 - Sayı: 1, 1–4. https://ajindex.com/articles/495601

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (5)

  1. Thygesen K, Alpert JS, Jaffe AS, Simoons ML, Chaitman BR, White HD.Third Universal Definition of Myocardial Infarction ESC/ACCF/AHA/WHF EXPERT CONSENSUS DOCUMENT,CirculationVolume 126, Issue 16, 16 October 2012, Pages 2020-2035
  2. Ward G, Simpson A, LBoscato L, Hickman PE,.The investigation of interferences in immunoassay, Clinical Biochemistry, Volume 50, Issue 18, December 2017, Pages 1306-1311
  3. Khan IA, Wattanasuwan N, Mehta NJ, Tun A, Singh N, et al. Prognostic value of serum cardiac troponinI in ambulatory patients with chronic renal failure undergoing long-term hemodialysis:a two-year outcome analysis. JACC. 2001 Oct;38(4):991–8
  4. Cardiac Markers, second press, edited Alan H. B. Wu, Springer Science & Business Media, 2003, New York
  5. Franeková J, Bláha M, Bělohoubek J, Kotrbatá M, Peter Sečník P, at al,. A Clinical and Laboratory Approach Used to Elucidate Discordant Results of High-Sensitivity TroponinT and TroponinI. Clin Chim Acta. 2015 Jun 15;446:128-31.