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Journals / Ege Klinikleri Tıp Dergisi / 2021 / Cilt: 59 - Sayı: 2

Assessment of The Effect of Intrathecal Bupivacaine Combined With Opioids on Postoperative Analgesia in Patients Undergoing Cesarean Section

Sezaryen Operasyonlarında Spinal Anestezide Lokal Anesteziklere İlave Edilen Opioidlerin Postoperatif Ağrı Üzerine Etkisinin Karşılaştırılması

Derya KARASU
Filiz ATA
Gülsen KORFALI
Canan YILMAZ
Mine AKÖZ
Ferit YETİK
Pages
1–6
Publication Date
2022-10-11
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Intraoperative pruritus was found to be significantly higher in Group M100 than the other two groups (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Background: The aim of our study is to compare the effects of two different doses of morphine added to bupivacaine and fentanyl in cesarean section performed with spinal anesthesia.
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Key Findings & Data:Materials and Methods: Patients with gestational age above 37 weeks, over 18 years of age and underwent cesarean section with spinal anesthesia were included in the study.
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Conclusion & Impact:Intraoperative pruritus was found to be significantly higher in Group M100 than the other two groups (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background: The aim of our study is to compare the effects of two different doses of morphine added to bupivacaine and fentanyl in cesarean section performed with spinal anesthesia. Materials and Methods: Patients with gestational age above 37 weeks, over 18 years of age and underwent cesarean section with spinal anesthesia were included in the study. Patients Group M0 (8 mg 5% hyperbaric bupivacaine + 20 mcg fentanyl), Group M50 (8 mg 5% hyperbaric bupivacaine + 20 mcg fentanyl + 50 mcg morphine) and Group M100 (8 mg 5% hyperbaric bupivacaine + 20 mcg fentanyl + 100 mcg morphine) divided into three groups. Intraoperative visual analog scale (VAS) values, intraoperative and postoperative complications, and the first postoperative analgesia time were compared. Results: 1090 patients were included in statistical evaluation. Intraoperative nausea and vomiting were found significantly less in Group M100 compared to the other two groups (p=0.047). Intraoperative pruritus was found to be significantly higher in Group M100 than the other two groups (p

Özet

Amaç: Çalışmamızın amacı spinal anestezi ile yapılan sezaryen operasyonlarında, bupivakain ve fentanile ilave edilen iki farklı morfin dozunun etkilerini incelemektir. Gereç ve Yöntemler: Gestasyonel yaşı 37 haftanın üzerinde olan, 18 yaş üstü ve spinal anestezi ile sezaryen operasyonu uygulanan hastalar çalışmaya dahil edildi. Hastalar Grup M0 (8 mg %5 hiperbarik bupivakain+20 mcg fentanil), Grup M50 (8 mg %5 hiperbarik bupivakain+20 mcg fentanil + 50 mcg morfin) ve Grup M100 (8 mg %5 hiperbarik bupivakain + 20 mcg fentanil + 100 mcg morfin) olarak üç gruba ayrıldı. İntraoperatif vizüel analog skala (VAS) değerleri, intraoperatif ve postoperatif komplikasyonlar ve postoperatif dönemde uygulanan ilk analjezi zamanı karşılaştırıldı. Bulgular: İstatistiksel değerlendirmeye 1090 hasta alındı. İntraoperatif bulantı, kusma Grup M100’de diğer iki gruba göre anlamlı az bulundu (p=0.047). İntraoperatif kaşıntı Grup M100’de diğer iki gruba göre anlamlı fazla bulundu (p

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Cite This Article

KARASU, D., ATA, F., KORFALI, G., YILMAZ, C., AKÖZ, M., YETİK, F. (2022). Assessment of The Effect of Intrathecal Bupivacaine Combined With Opioids on Postoperative Analgesia in Patients Undergoing Cesarean Section. Ege Klinikleri Tıp Dergisi, Cilt: 59 - Sayı: 2, 1–6. https://ajindex.com/articles/495593

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