AI Summary & Key Takeaways
AI InsightResults: In the evaluation of blood pressure, prehypertension was detected in 4 cases and HT in 5 cases in the MCKD group, while prehypertension was detected in one case and hypertension in one patient in the control group (p
📌 3 Key Takeaways
Abstract
Objective: In this study, it is aimed to determine the characteristic features and incidence of hypertension and also associated risk factors in children with unilateral multicystic dysplastic kidney disease (MCKD). Methods: In the first step of the study, data of eighty-seven patients with unilateral MCKD who have been followed between the years of 1993 and 2010 were investigated retrospectively. In the second step, twenty-two voluntary patients with unilateral MCKD and twenty-two healthy children with similar sex and age were included into the study. 24-h ambulatory blood pressure monitoring (ABPM) was performed to all of children and incidence of hypertension was investigated. Blood and urine samples were taken from two groups. Blood chemistry parameters, plasma renin activity, aldosterone, angiotensin and also urine protein and microalbumin were measured. Results: In the evaluation of blood pressure, prehypertension was detected in 4 cases and HT in 5 cases in the MCKD group, while prehypertension was detected in one case and hypertension in one patient in the control group (p
Özet
Amaç: Bu çalışmada, unilateral multikistik displastik böbrek hastalığı (MDBH) olan çocuklarda hipertansiyonun karakteristik özellikleri ve insidansı ile ilişkili risk faktörlerinin belirlenmesi amaçlanmıştır. Materyal ve Metot: Çalışmanın ilk aşamasında, 1993-2010 yılları arasında takip edilen tek taraflı MKBH'li seksen yedi hastanın verileri geriye dönük olarak incelendi. İkinci aşamada, tek taraflı MKBH'li 22 gönüllü hasta ve benzer cinsiyet ve yaştaki 22 sağlıklı çocuk çalışmaya dahil edildi. Tüm çocuklara 24 saatlik ambulatuar kan basıncı takibi (AKBT) yapıldı ve hipertansiyon insidansı araştırıldı. İki gruptan kan ve idrar örnekleri alındı. Kan kimyası parametreleri, plazma renin aktivitesi, aldosteron, anjiyotensin ve ayrıca idrar proteini ve mikroalbümin ölçüldü. Bulgular: Kan basıncı değerlendirmesinde MKBH grubunda 4 olguda prehipertansiyon, 5 olguda HT, kontrol grubunda 1 olguda prehipertansiyon ve 1 hastada hipertansiyon saptandı (p