Journals / Ege Klinikleri Tıp Dergisi / 2021 / Cilt: 59 - Sayı: 2

Does COVID-19 Cause Intrauterine Fetal Death? A Case Report

COVID-19 İntrauterin Fetal Ölüme Neden Olur mu? Olgu Sunumu

Pages
1–4
Publication Date
2022-10-11
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The fetal autopsy was performed after termination of pregnancy.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:It has been proposed that pregnant women and their fetuses may be particularly at risk for poor outcomes due to the coronavirus pandemic.
📊
Key Findings & Data:However, it is not known whether coronavirus disease (COVID-19) is associated with a higher risk of miscarriage or stillbirth.
💡
Conclusion & Impact:The fetal autopsy was performed after termination of pregnancy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

It has been proposed that pregnant women and their fetuses may be particularly at risk for poor outcomes due to the coronavirus pandemic. However, it is not known whether coronavirus disease (COVID-19) is associated with a higher risk of miscarriage or stillbirth. Therefore, in this report, we present a case of fetal death during the second trimester due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. A 20 years old pregnant was presented at 22 weeks of gestation to the perinatology department with a chief complaint of pelvic pain. Her nasopharyngeal swab was tested positive for SARS-COV-2 using real time polymerase chain reaction (RT-PCR) eleven days ago. Mild symptoms of patient such as fever and arthralgia were relieved without medication during COVID-19. Her past obstetric history was unremarkable. The results of ultrasound scan revealed intrauterine fetal demise with a normal fetal anatomy and amniotic fluid. The fetal autopsy was performed after termination of pregnancy.

Özet

Koronovirüs pandemisinden dolayı gebelerin ve fetüslerin kötü perinatal sonuçlar açısından özellikle risk altında oldukları öne sürülmektedir. Ancak, koronavirüs hastalığının (COVID-19) abortus veya ölü doğum için yüksek riskle birlikte olup olmadığı bilinmemektedir. Bundan dolayı, bu çalışmada ikinci trimesterde ağır akut solunum sendromu koronavirüsü 2’nin (SARS-COV-2) enfeksiyonuna bağlı gelişen bir fetal ölüm olgusu sunulmaktadır. Yirmi yaşında bir gebe 22. gestasyonel haftasında başlıca pelvik ağrı şikayetiyle perinatoloji kliniğine başvurdu. Hastanın on bir gün önce gerçek zamanlı polimeraz zincir reaksiyonu (RT-PCR) kullanılarak yapılan nazofaringeal sürüntüsü SARS-COV-2 için pozitifti. Hastanın COVID-19 sırasında ateş ve eklem ağrısı gibi hafif semptomları ilaç kullanmadan gerilemişti. Hastanın obstetrik öyküsünde herhangi bir anormallik yoktu. Ultrason tarama sonuçları normal anatomi ve amnion mai ile birlikte intrauterin fetal ölümü ortaya çıkardı. Gebeliğin terminasyonu sonrası fetal otopsi yapıldı.

🔖

Cite This Article

ÖMEROĞLU, İ., GÖLBAŞI, H., EKİN, A. (2022). Does COVID-19 Cause Intrauterine Fetal Death? A Case Report. Ege Klinikleri Tıp Dergisi, Cilt: 59 - Sayı: 2, 1–4. https://ajindex.com/articles/495574

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (9)

  1. Poon LC, Yang H, Lee JC, Copel JA, Leung TY, Zhang Y, et al. ISUOG Interim Guidance on 2019 novel coronavirus infection during pregnancy and puerperium: information for healthcare professionals. Ultrasound Obstet Gynecol. 2020 doi: 10,1002/uog.22013
  2. Alfaraj S.H., Al-Tawfiq J.A., Memish Z.A. Middle East respiratory syndrome coronavirus (MERS-CoV) infection during pregnancy: report of two cases and review of the literature. J Microbiol Immunol Infect. 2019;52:501–503
  3. Maxwell C, McGeer A, Tai KFY, Sermer M. No. 225-Management guidelines for obstetric patients and neonates born to mothers with suspected or probable Severe Acute Respiratory Syndrome (SARS) J Obstet Gynaecol Canada. 2017;39(39):e130-e17
  4. Chen W. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. Lancet. 2020;395(10226):809–815 5. Liu Y., Chen H., Tang K., Guo Y. Clinical manifestations and outcome of SARS-CoV-2 infection during pregnancy. J Infect. 2020
  5. Zhang L., Zhang L., Jiang Y. Analysis of the pregnancy outcomes in pregnant women with COVID-19 in Hubei Province. Zhonghua Fu Chan Ke Za Zhi. 2020;55:E009
  6. Chen S., Chen S., Huang B. Pregnant women with new coronavirus infection: a clinical characteristics and placental pathological analysis of three cases. Zhonghua Bing Li Xue Za Zhi. 2020;49:E005
  7. Levy A., Yagil Y., Bursztyn M., Barkalifa R., Scharf S., Yagil C. ACE2 expression and activity are enhanced during pregnancy. Am J Physiol Regul Integr Comp Physiol. 2008;295:1953–196133
  8. Woodworth KR, Olsen EO, Neelam V, et al. Birth and Infant Outcomes Following Laboratory-Confirmed SARS-CoV-2 Infection in Pregnancy - SET-NET, 16 Jurisdictions, March 29-October 14, 2020. MMWR Morb Mortal Wkly Rep 2020; 69:1635
  9. Jeong Yee, Woorim Kim, Ji Min Han, Ha Young Yoon, Nari Lee, Kyung Eun Lee, Hye Sun Gwak. Clinical manifestations and perinatal outcomes of pregnant women with COVID-19: a systematic review and meta-analysis. Sci Rep. 2020; 10: 18126. Published online 2020 Oct 22. doi: 10.1038/s41598-020-75096-4 11. Hraiech S, Bourenne J, Kuteifan K, Helms J, Carvelli J, Gainnier M, Meziani F, Papazian L. Lack of viral clearance by the combination of hydroxychloroquine and azithromycin or lopinavir and ritonavir in SARS-CoV-2-related acute respiratory distress syndrome Ann Intensive Care. 2020 May 24;10(1):63 12. Burwick RM, Yawetz S, Stephenson KE, Collier A-RY, Sen P