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Journals / Düzce Üniversitesi Bilim ve Teknoloji Dergisi / 2017 / Cilt: 5 - Sayı: 2

Investigation The Antimutagenic Effects Of Smilax Excelsa L. Extracts By Ames/Salmonella/Microsome Test System

Smilax Excelsa L. Ekstraktlarının Ames/Salmonella/Mikrozom Test Sistemi İle Antimutajenik Etkisinin Araştırılması

Emine YALÇIN
Kültiğin ÇAVUŞOĞLU
Elvan AZAP
Pages
622–631
Publication Date
2022-10-12
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

And also all the extracts of Smilax excelsa L. showed antimutagenic activity with different rates .

📌 3 Key Takeaways

🎯
Objective & Hypothesis:In this study, leaf and fruit extracts of Smilax excelsa L., were investigated for antimutagenic activity by Ames/Salmonella/microsome test method.
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Key Findings & Data:Fruit and leaf extracts was not observed the cytotoxic effect in the range of 10-100 mg/mL doses.
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Conclusion & Impact:And also all the extracts of Smilax excelsa L. showed antimutagenic activity with different rates .
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Smilax excelsa L. · Ames/Salmonella/mikrozom test sistemi · Antimutajenik aktivite

Abstract

In this study, leaf and fruit extracts of Smilax excelsa L., were investigated for antimutagenic activity by Ames/Salmonella/microsome test method. Fruit and leaf extracts was not observed the cytotoxic effect in the range of 10-100 mg/mL doses. Antimutagenity analysis were studies with S9(+) and S9(-) on Salmonella typhimurium TA 98 and TA 100 strains. Maximum antimutagenic activity was observed with leaf extracts at 100 mg/plaque dose on TA98 strain in the absence of S9 as 88%. And also all the extracts of Smilax excelsa L. showed antimutagenic activity with different rates .

Özet

Bu çalışmada, Smilax excelsa L. yaprak ve meyve ekstraktlarının antimutajenik aktiviteleri Ames/Salmonella/mikrozom test yöntemi ile incelenmiştir. Smilax excelsa L. yaprak ve meyve ekstraktlarının 10-100 mg/mL doz aralığında sitotoksik etki göstermediği belirlenmiştir. Antimutajenite çalışmaları S9 (+) ve S9 (-) olmak üzere Salmonella typhimurium TA98 ve TA100 suşları ile gerçekleştirilmiştir. Maksimum antimutajenik etki yaprak ekstraktı ile 100 mg/plak dozunda TA98 suşu üzerine S9 karışımı yokluğunda %88 olarak elde edilmiştir. Ayrıca, Smilax excelsa L. bitkisinin tüm ekstraktlarının farklı oranlarda antimutajenik aktiviteye sahip oldukları belirlenmiştir.

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Cite This Article

YALÇIN, E., ÇAVUŞOĞLU, K., AZAP, E. (2022). Investigation The Antimutagenic Effects Of Smilax Excelsa L. Extracts By Ames/Salmonella/Microsome Test System. Düzce Üniversitesi Bilim ve Teknoloji Dergisi, Cilt: 5 - Sayı: 2, 622–631. https://ajindex.com/articles/494587

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