Journals / Düzce Üniversitesi Bilim ve Teknoloji Dergisi / 2019 / Cilt: 7 - Sayı: 3

Zebrafish (Danio rerio) In Pesticide-Induced Cardiac Toxicity Research

Pestisit Kaynaklı Kardiyak Toksisite Araştırmalarında Zebra Balığı (Danio rerio)

Pages
1417–1430
Publication Date
2022-10-12
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, it was mentioned in detail that why in recent years zebrafish is considered as a model system to evaluate the heart abnormalities that occurs due to pesticide exposure.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Environmental pollutants give rise to several health problems beside degenerations in terrestrial and aquatic ecosystems.
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Key Findings & Data:Pesticides are the chemicals that spread to the environment through continuous usage, move and show biological effects on non-target organisms that they encounter in various environmental phases.
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Conclusion & Impact:In this review, it was mentioned in detail that why in recent years zebrafish is considered as a model system to evaluate the heart abnormalities that occurs due to pesticide exposure.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Environmental pollutants give rise to several health problems beside degenerations in terrestrial and aquatic ecosystems. Pesticides are the chemicals that spread to the environment through continuous usage, move and show biological effects on non-target organisms that they encounter in various environmental phases. It has thought that pesticides are also related to cardiovascular diseases. Laboratory works are essential to search the possible effects of these chemicals on heart. Zebrafish (Danio rerio) is considered as a model organism that presents numerous advantages to researchers on their both adult and embryonic stages on cardiac toxicity studies. In recent years, zebrafish have been often preferred to reveal the toxic effects of pesticides on the heart and to investigate their modes of action. In this review, it was mentioned in detail that why in recent years zebrafish is considered as a model system to evaluate the heart abnormalities that occurs due to pesticide exposure.

Özet

Çevresel kirleticiler, karasal ve sucul ekosistemlerde bozulmalara sebep olmalarının yanı sıra pek çok sağlıksorununa da yol açmaktadır. Pestisitler, devamlı kullanımla çevreye yayılan, hareket eden, farklı çevre fazlarındakarşılaştıkları hedef dışı organizmalarda biyolojik etki gösteren kirleticiler olarak bilinmektedir. Pestisitlerinkardiyovasküler hastalıklarla da ilişkili oldukları düşünülmektedir. Bu kimyasalların kalpte meydanagetirebilecekleri olası etkilerin araştırılmasında laboratuvar çalışmalarının önemi büyüktür. Zebra balığı (Daniorerio), kardiyak toksisite çalışmalarında gerek embriyonik gerekse ergin dönemde araştırıcılara sayısız kolaylıksağlayan bir model organizma olarak kabul edilmektedir. Pestisitlerin kalp üzerindeki toksik etkilerinin ortayakonması ve etki mekanizmalarının araştırılmasında son yıllarda zebra balıkları sıklıkla kullanılmaktadır. Buderlemede, pestisit maruziyetine bağlı ortaya çıkan kalp anomalilerinin değerlendirilmesinde neden son yıllardazebra balığının model sistem olarak kabul edildiğine ayrıntıları ile değinilmiştir.

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Cite This Article

ARMAN, S. (2022). Zebrafish (Danio rerio) In Pesticide-Induced Cardiac Toxicity Research. Düzce Üniversitesi Bilim ve Teknoloji Dergisi, Cilt: 7 - Sayı: 3, 1417–1430. https://ajindex.com/articles/494424

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