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Journals / Düzce Üniversitesi Bilim ve Teknoloji Dergisi / 2019 / Cilt: 7 - Sayı: 1

Antibacterial and Anti-Urease Activities of Chloropheniramine maleat, Paracetamol and Clarithromycine

Klorofeniramin Maleat, Parasetamol ve Klaritromisin’in Antibakteriyal ve Anti-Ureaz Aktiviteleri

Sinem AYDIN
Pages
194–200
Publication Date
2022-10-12
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Furthermore, it is thought that paracetamol has antibacterial properties and therefore can be used as an alternative to antibiotics

📌 3 Key Takeaways

🎯
Objective & Hypothesis:This paper presents anti-urease and antibacterial activities of chloropheniramine maleat, paracetamol and clarithromycine.
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Key Findings & Data:All tested compounds demonstrated antibacterial action with varying degree except for chloropheniramine maleat.
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Conclusion & Impact:Furthermore, it is thought that paracetamol has antibacterial properties and therefore can be used as an alternative to antibiotics
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Antibiyotik · Klaritromisin · Klorofeniramin maleat

Abstract

This paper presents anti-urease and antibacterial activities of chloropheniramine maleat, paracetamol and clarithromycine. Antibacterial activity of the compounds was investigated against Salmonella enterica, Enterobacter aerogenes, Bacillus subtilis, Proteus vulgaris, Gordonia rubripertincta, Klebsiella pneumoniae and Enterococcus faecalis. Moreover, anti-urease activity of the compounds was searched. All tested compounds demonstrated antibacterial action with varying degree except for chloropheniramine maleat. Chloropheniramine maleat, paracetamol and chlarithromycine exhibited higher activity than thiourea. The data obtained from the study, chloropheniramine maleate, paracetamol and clarithromycin are thought to be useful as new urease inhibitors and the present study should be supported by further studies. Furthermore, it is thought that paracetamol has antibacterial properties and therefore can be used as an alternative to antibiotics

Özet

Bu çalışmada klorofeniramin maleat, parasetamol ve klaritromisin’in antibakteriyal ve anti-üreaz aktiviteleri ile ilgilenmektedir. Maddelerin antibakteriyal aktiviteleri Salmonella enterica, Enterobacter aerogenes, Bacillus subtilis, Proteus vulgaris, Gordonia rubripertincta, Klebsiella pneumoniae, Bacillus megaterium ve Enterococcus faecalis’e karşı araştırıldı. Bu maddelerin anti-üreaz aktiviteleri de incelendi. Klorofeniramin maleat dışında, test edilen tüm bileşikler değişik oranlarda antibakteriyal etki gösterdi. Klorofeniramin maleat, parasetamol ve klaritromisin tiyoüreden daha yüksek aktivite gösterdi. Çalışmadan elde edilen veriler, klorofeniramin maleat, parasetamol ve klaritromisin yeni üreaz inhibitörü olarak kullanılabileceğini düşünülmüş olup mevcut çalışma daha ileri çalışmalar ile de desteklenmelidir. Ayrıca, parasetamolün antibakteriyel özelliklere sahip olduğu ve bu nedenle antibiyotiklere alternatif olarak kullanılabileceği düşünülmektedir.

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Cite This Article

AYDIN, S. (2022). Antibacterial and Anti-Urease Activities of Chloropheniramine maleat, Paracetamol and Clarithromycine. Düzce Üniversitesi Bilim ve Teknoloji Dergisi, Cilt: 7 - Sayı: 1, 194–200. https://ajindex.com/articles/494338

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