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Journals / Düzce Üniversitesi Bilim ve Teknoloji Dergisi / 2020 / Cilt: 8 - Sayı: 3

A Vortex-Assisted Microextraction Based On Deep Eutectic Solvents for Determination of Four Parabens from Cosmetic Baby Oils and Optimization by Box-Behnken Design

Kozmetik Bebek Yağlarında Dört Parabenin Tayini için Derin Ötektik Çözücülere Dayanan Vorteks Destekli Mikro Ekstraksiyon ve BoxBehnken Tasarımı ile Optimizasyon

Sezen Sivrikaya Özak
Pages
1936–1947
Publication Date
2022-10-12
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This developed method isvery suitable and effective method for the extraction of parabens from cosmetic products of similar structure.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:This study presents microextraction and determination of four parabens by vortex-assisted microextraction basedon deep eutectic solvents (DESs) in cosmetic baby oils.
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Key Findings & Data:The most suitable DES, ChCl-ethylene glycol moleratios of DES were determined as 1:2 for use in this study.
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Conclusion & Impact:This developed method isvery suitable and effective method for the extraction of parabens from cosmetic products of similar structure.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

This study presents microextraction and determination of four parabens by vortex-assisted microextraction basedon deep eutectic solvents (DESs) in cosmetic baby oils. The most suitable DES, ChCl-ethylene glycol moleratios of DES were determined as 1:2 for use in this study. The effect of DES types has been explored attraditional one factor experiment at a time. The effect of DES volume, dilution solvent volume and vortex timeon extraction recovery were examined and optimized by the Box-Behnken design. After optimum conditionswere determined, vortex-assisted microextraction based on DES, 0.1-100 µg mL-1concentration in the range ofthe calibration curve was plotted for all parabens. The recovery values of parabens in cosmetic baby oil sampleswere in the range of 82.02-101.95% and the RSDs were varied from 1.64% to 2.91%. This developed method isvery suitable and effective method for the extraction of parabens from cosmetic products of similar structure.

Özet

Bu çalışma kozmetik bebek yağlarında derin ötektik çözücülere (DES'ler) dayalı vorteks destekli mikroekstraksiyon ile dört parabenin mikro ekstraksiyonu ve tayinini sunmaktadır. En uygun DES, ChCl-etilen glikol mol oranları bu çalışmada kullanılmak üzere 1:2 olarak belirlenmiştir. DES türlerinin etkisi, geleneksel tek faktörlü deneyde araştırılmıştır. DES hacmi, seyreltme çözücü hacmi ve vorteks süresinin ekstraksiyon geri kazanımı üzerindeki etkisi Box-Behnken tasarımı ile incelenmiş ve optimize edilmiştir. Optimum koşullar belirlendikten sonra, DES'e dayalı vorteks destekli mikro ekstraksiyon, kalibrasyon eğrisi 0.1-100 µg mL-1 konsantrasyon tüm parabenler için çizildi. Kozmetik bebek yağı numunelerindeki parabenlerin geri kazanım değerleri % 82.02-101.95 aralığındadır ve RSD'ler %1.64 ile %2.91 arasında değişmektedir. Bu geliştirilen yöntem, benzer yapıdaki kozmetik ürünlerden parabenlerin ekstraksiyonu için çok uygun ve etkili bir yöntemdir.

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Cite This Article

Özak, S. S. (2022). A Vortex-Assisted Microextraction Based On Deep Eutectic Solvents for Determination of Four Parabens from Cosmetic Baby Oils and Optimization by Box-Behnken Design. Düzce Üniversitesi Bilim ve Teknoloji Dergisi, Cilt: 8 - Sayı: 3, 1936–1947. https://ajindex.com/articles/494109

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