Journals / Düşünen Adam - Psikiyatri ve Nörolojik Bilimler Dergisi / 2018 / Cilt: 31 - Sayı: 2

Mirtazapine-related manic / hypomanic shift: mini review and case report

Mirtazapin ilişkili manik / hipomanik kayma: Mini derleme ve olgu sunumu

Pages
209–214
Publication Date
2022-10-11
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This mini-review and case report aimed to compile case reports on mirtazapine related manicshifts and to report a case where a manic shift was determined relatively early compared to that in thesecases.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Mirtazapine is a pharmacological agent frequently used both as an antidepressant and as a hypnoticsedative agent.
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Key Findings & Data:However, manic shift, an important side effect of other antidepressants, has not beenadequately addressed in the treatment of mirtazapine, and the evidence has been only available fromcase reports.
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Conclusion & Impact:This mini-review and case report aimed to compile case reports on mirtazapine related manicshifts and to report a case where a manic shift was determined relatively early compared to that in thesecases.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Mirtazapine is a pharmacological agent frequently used both as an antidepressant and as a hypnoticsedative agent. However, manic shift, an important side effect of other antidepressants, has not beenadequately addressed in the treatment of mirtazapine, and the evidence has been only available fromcase reports. This mini-review and case report aimed to compile case reports on mirtazapine related manicshifts and to report a case where a manic shift was determined relatively early compared to that in thesecases.

Özet

Mirtazapin hem antidepresan olarak hem de hipnotik sedatif etkisi nedeni ile sıkça kullanılan bir farmakolojik ajandır. Ancak diğer antidepresanlarda önemli bir yan etki olan manik kayma, mirtazapin tedavisinde yeterince ele alınmamış, kanıtlar genellikle olgu sunumu aşamasında kalmıştır. Bu mini-derleme ve olgu sunumunda mirtazapinle ilişkili manik kayma ile ilgili olgu sunumlarını derleyerek, bu olgulara göre çok daha kısa sürede manik kaymanın izlendiği bir vakanın sunulması planlanmıştır.

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Cite This Article

DİNCER, M., GUL, A., BODUR, S., OZMENLER, K. N., TORUN, Y. T., AYDİN, M. S., CONGOLOGLU, M. A., GUL, H. (2022). Mirtazapine-related manic / hypomanic shift: mini review and case report. Düşünen Adam - Psikiyatri ve Nörolojik Bilimler Dergisi, Cilt: 31 - Sayı: 2, 209–214. https://ajindex.com/articles/493714

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References (2)

  1. de Boer T. The effects of mirtazapine on central noradrenergic and serotonergic neurotransmission. Int Clin Psychopharmacol 1995; 10(Spull.4):19-23.
  2. Wichniak A, Wierzbicka A, Jernajczyk W. Sleep and antidepressant treatment. Curr Pharm Des 2012; 18:5802-5817. [CrossRef] Wichniak A, Wierzbicka A, Jernajczyk W. Sleep and antidepressant treatment. Curr Pharm Des 2012; 18:5802-5817. [CrossRef] Allain N, Leven C, Falissard B, Allain JS, Batail JM, Polard E, Montastruc F, Drapier D, Naudet F. Manic switches induced by antidepressants: an umbrella review comparing randomized controlled trials and observational studies. Acta Psychiatr Scand 2017; 135:106-116. [CrossRef] Koszewska I, Rybakowski JK. Antidepressant-induced mood conversions in bipolar disorder: a retrospective study of tricyclic versus non-tricyclic antidepressant drugs. Neuropsychobiology 2009; 59:12-16. [CrossRef] Post RM, Altshuler LL, Leverich GS, Frye MA, Nolen WA, Kupka RW, Suppes T, McElroy S, Keck PE, Denicoff KD, Grunze H, Walden J, Kitchen CM, Mintz J. Mood switch in bipolar depression: comparison of adjunctive venlafaxine, bupropion and sertraline. Br J Psychiatry 2006; 189:124-131. [CrossRef] Pacchiarotti I, Bond DJ, Baldessarini RJ, Nolen WA, Grunze H, Licht RW, Post RM, Berk M, Goodwin GM, Sachs GS, Tondo L, Findling RL, Youngstrom EA, Tohen M, Undurraga J, González-Pinto A, Goldberg JF, Yildiz A, Altshuler LL, Calabrese JR, Mitchell PB, Thase ME, Koukopoulos A, Colom F, Frye MA, Malhi GS, Fountoulakis KN, Vázquez G, Perlis RH, Ketter TA, Cassidy F, Akiskal H, Azorin JM, Valentí M, Mazzei DH, Lafer B, Kato T, Mazzarini L, Martínez-Aran A, Parker G, Souery D, Ozerdem A, McElroy SL, Girardi P, Bauer M, Yatham LN, Zarate CA, Nierenberg AA, Birmaher B, Kanba S, El-Mallakh RS, Serretti A, Rihmer Z, Young AH, Kotzalidis GD, MacQueen GM, Bowden CL, Ghaemi SN, Lopez-Jaramillo C, Rybakowski J, Ha K, Perugi G, Kasper S, Amsterdam JD, Hirschfeld RM, Kapczinski F, Vieta E. The International Society for Bipolar Disorders (ISBD) task force report on antidepressant use in bipolar disorders. Am J Psychiatry 2013; 170:1249-1262. [CrossRef] Benazzi F. Antidepressant-associated hypomania in outpatient depression: a 203-case study in private practice. J Affect Disord 1997; 46:73-77. [CrossRef] Boerlin HL, Gitlin MJ, Zoellner LA, Hammen CL. Bipolar depression and antidepressant-induced mania: a naturalistic study. J Clin Psychiatry 1998; 59:374-379. [CrossRef] De León OA, Furmaga KM, Kaltsounis J. Mirtazapin