Journals / İstanbul Tıp Fakültesi Dergisi / 2019 / Cilt: 82 - Sayı: 1

COMPARISON OF OVERALL SURVIVAL AND DISEASE-FREE SURVIVAL IN SEROUS ENDOMETRIAL CANCER AND UTERINE CARCINOSARCOMA

SERÖZ ENDOMETRİAL KANSER VE UTERİN KARSİNOSARKOMDA GENEL SAĞKALIM VE HASTALIKSIZ SAĞKALIMIN KARŞILAŞTIRILMASI

Pages
1–4
Publication Date
2019-03-28
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Objective: The aim of this study was to compare the survival durations of patients with uterine carcinosarcoma with the survival of patients with serous endometrial cancer.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: The aim of this study was to compare the survival durations of patients with uterine carcinosarcoma with the survival of patients with serous endometrial cancer.
📊
Key Findings & Data:Objective: The aim of this study was to compare the survival durations of patients with uterine carcinosarcoma with the survival of patients with serous endometrial cancer.
💡
Conclusion & Impact:Objective: The aim of this study was to compare the survival durations of patients with uterine carcinosarcoma with the survival of patients with serous endometrial cancer.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Endometrium kanseri · sağkalım · karsinom

Abstract

Objective: The aim of this study was to compare the survival durations of patients with uterine carcinosarcoma with the survival of patients with serous endometrial cancer.

Özet

Amaç: Bu çalışmanın amacı uterin karsinosarkomlu hastaların yaşam süresini, seröz endometrial kanserli hastaların yaşam süreleri ile karşılaştırmaktı.Yöntem: 2002-2014 yılları arasında endometriyal kanser nedeniyle opere edilen hastalar klinik arşivinden tarandı. Çalışmaya histolojik tümör tipi karsinosarkom veya seröz tip olan hastalar dahil edildi.Bulgular: Toplam hasta sayısı 99; bunların 53’ünde karsinosarkom, 46’sında seröz histoloji saptandı. Medyan hastalıksız sağkalım süresi karsinosarkomda 20 (2-27) ay ve seröz tipte 36 (3-180) aydı (Log-Rank testi p=0,156). Medyan sağkalım süresi karsinosarkom için 28 (4-170) ay, seröz için 46 (3-180) aydı (p=0,105). Beş yıllık genel sağkalım oranı, karsinosarkom histolojisinde %41,2 iken, seröz histolojide %55,4 idi. Nüksten sonra, karsinosarkom histolojisi olan hastalar ortalama 8 (1-19) ay, seröz histolojisi olanlar ortalama 14 (2-43 ay) yaşamışlardı (p=0,090).Sonuç: Log-Rank test analizi sonuçlarına göre, uterin karsinosarkomlu ve seröz endometriyal kanserli hastalar arasında istatistiksel olarak anlamlı bir sağkalım farkı bulunmadı. Bununla birlikte, hastalıksız sağkalım, genel sağkalım ve nüks sonrası sağkalım süresi seröz histolojide karsinosarkomdan daha uzundur.

🔖

Cite This Article

KABAN, A., TOPUZ, S., SOZEN, H., SALİHOGLU, Y. (2019). COMPARISON OF OVERALL SURVIVAL AND DISEASE-FREE SURVIVAL IN SEROUS ENDOMETRIAL CANCER AND UTERINE CARCINOSARCOMA. İstanbul Tıp Fakültesi Dergisi, Cilt: 82 - Sayı: 1, 1–4. https://ajindex.com/articles/48424

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (11)

  1. Moore KN, Fader AN. Uterine papillary serous carcinoma. Clin Obstet Gynecol 2011;54(2):278–91
  2. Ferrandina G, Zannoni GF, Martinelli E, Vellone V, Prisco MG, Scambia G. Endometrial carcinoma recurring as carcinosarcoma: Report of two cases. Pathol Res Pract 2007;203(9):677–81
  3. NCCN. NCCN Clinical Practice Guidelines in Oncology: Uterine Neoplasms. Nccn. 2015;
  4. Spaziani E, Picchio M, Petrozza V, Briganti M, Ceci F, Di Filippo A, et al. Carcinosarcoma of the uterus: A case report and review of the literature. Eur J Gynaecol Oncol 2008;29(5):531–4
  5. Singh R. Review literature on uterine carcinosarcoma. J Cancer Res Ther 2014;10(3):461–8
  6. Zhang C, Hu W, Jia N, Li Q, Hua K, Tao X, et al. Uterine carcinosarcoma and high-risk endometrial carcinomas: A clinicopathological comparison. Int J Gynecol cancer 2015;25(30973185):629–36
  7. Piver MS, Lele SB, Marchetti DL, Emrich LJ. Effect of adjuvant chemotherapy on time to recurrence and survival of stage I uterine sarcomas. J Surg Oncol 1988;38(4):233–9
  8. Gadducci A, Fabrini MG, Facchini V, Ducci F, Colosimo S, Dell’Arciprete T, et al. Surgery and radiotherapy in the treatment of early stage uterine sarcomas. Eur J Gynaecol Oncol 1989;10(4):276–80
  9. Hamilton C, Cheung M, Osann K, Chen L, Teng N, Longacre T, et al. Uterine papillary serous and clear cell carcinomas predict for poorer survival compared to grade 3 endometrioid corpus cancers. Br J Cancer 2006;94(5):642–6
  10. Üreyen I, Karalok A, Cırık DA, Taşçı T, Türkmen O, Cömert GK, et al. A comparison of clinico-pathologic characteristics of patients with serous and clear cell carcinoma of the uterus. Turk J Obs Gynecol 2016;13(3):137–43
  11. Felix AS, Stone RA, Bowser R, Chivukula M, Edwards RP, Weissfeld JL, et al. Comparison of survival outcomes between patients with malignant mixed mullerian tumors and high-grade endometrioid, clear cell, and papillary serous endometrial cancers. Int J Gynecol Cancer 2011;21(5):877–84.