For 47 compounds, conformational analysis and quantum chemical calculations were done, and unit matrix representing electronic character was calculated, and active fragment in the active compounds were extracted.
📌 3 Key Takeaways
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Objective & Hypothesis:Relationship structure-antisecretory of a series of Imidazo[l,2,a]pyridinylethyl benzoxazole derivatives which is known to be either active-inactive or their activity which is known quantitatively are investigated theoretically with Electron Topological Method (ETM).
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Key Findings & Data:This technique can identify active fragment, related activity, belongs to the series of compounds and can quantitatively give the values of some compounds whose secretion activities cannot be measured experimentally.
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Conclusion & Impact:For 47 compounds, conformational analysis and quantum chemical calculations were done, and unit matrix representing electronic character was calculated, and active fragment in the active compounds were extracted.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Abstract
Relationship structure-antisecretory of a series of Imidazo[l,2,a]pyridinylethyl benzoxazole derivatives which is known to be either active-inactive or their activity which is known quantitatively are investigated theoretically with Electron Topological Method (ETM). This technique can identify active fragment, related activity, belongs to the series of compounds and can quantitatively give the values of some compounds whose secretion activities cannot be measured experimentally. For 47 compounds, conformational analysis and quantum chemical calculations were done, and unit matrix representing electronic character was calculated, and active fragment in the active compounds were extracted.
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Cite This Article
GÜZEL, Y., ACEMİOĞLU, B., SOYKATIRCI, M. (2022). Investigation of antisecretory activities of imidazo (1,2,a) pyridinylethylbenzoxazoles with the electron topological method. Cumhuriyet Üniversitesi Fen-Edebiyat Fakültesi Fen Bilimleri Dergisi, Cilt: 23 - Sayı: 1, 34–47. https://ajindex.com/articles/480434