According to the reducing power method,POSS-NAC structure has lower reducing activity than standard ascorbic acid and trolox(p
📌 3 Key Takeaways
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Objective & Hypothesis:In this study, polyhedral oligomeric silsesquioxane-N-acetylcysteine (POSS-NAC) conjugateas a potential antioxidant molecule was synthesized from N-acetylcysteine (NAC) and aminofunctionalPOSS structure by click chemistry.
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Key Findings & Data:The antioxidant capacity of the POSS-NAC conjugate was alsodetermined by the 2,2’-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radicalscavenging activity and reducing power methods.
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Conclusion & Impact:According to the reducing power method,POSS-NAC structure has lower reducing activity than standard ascorbic acid and trolox(p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Abstract
In this study, polyhedral oligomeric silsesquioxane-N-acetylcysteine (POSS-NAC) conjugateas a potential antioxidant molecule was synthesized from N-acetylcysteine (NAC) and aminofunctionalPOSS structure by click chemistry. The chemical structures and thermal propertiesof the synthesised POSS-NAC conjugate was characterized by spectroscopic and thermalanalysis techniques. The antioxidant capacity of the POSS-NAC conjugate was alsodetermined by the 2,2’-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radicalscavenging activity and reducing power methods. According to the reducing power method,POSS-NAC structure has lower reducing activity than standard ascorbic acid and trolox(p
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Cite This Article
KÖYTEPE, S., AÇARI, İ. K., BALCIOĞLU, S., SEÇKİN, T., ATEŞ, B., YILMAZ, İ. (2022). Synthesis of polyhedral oligomeric silsesquioxane-n-acetylcysteine conjugate with click chemistry and ıts antioxidant response and biocompatibility. Cumhuriyet Science Journal, Cilt: 41 - Sayı: 2, 386–396. https://ajindex.com/articles/477741
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