Journals / Communications Series:B Chemistry and Chemical Engineering / 2008 / Cilt: 54 - Sayı: 2

Gas chromatographic analysis of PS, PI, SPH and LPC Fatty acids in red blood cell membrane of rat, rabbit, human and dog

Pages
1–16
Publication Date
2022-10-11
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

C22:6 was present in rabbit, rat and human RBC membrane phospholipids but very little was present in dog.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Fatty acid analysis of red blood cell (RBC) membrane PS, PI, LPC and SPH were examined in species like rat, human, dog and rabbit by GC.
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Key Findings & Data:C16:0 and C18:0 were the prominent SFA (saturated fatty acids) in species phospholipids studied.
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Conclusion & Impact:C22:6 was present in rabbit, rat and human RBC membrane phospholipids but very little was present in dog.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Fatty acid analysis of red blood cell (RBC) membrane PS, PI, LPC and SPH were examined in species like rat, human, dog and rabbit by GC. C16:0 and C18:0 were the prominent SFA (saturated fatty acids) in species phospholipids studied. C16:0 was higher in LPC and SPH whereas C18:0 was higher in PS and PI in all species and in dog LPC. Although evenly spread in phospholipids, MUFA (monounsaturated fatty acid) in PS, PI and LPC seamed to be higher than in SPH. Among MUFA C16:1 and C18:1 were the prominent ones in the species, C18:1 being considerably higher than C16:1. PUFAs (polyunsaturated fatty acids) were relatively high in PS and PI compared to LPC and SPH in each species. Arachidonate was one of the most abundant fatty acids in human, rat and dog. Rabbit possessed very low levels of arachidonate in each phospholipid compared to that of other species phospholipids. By contrast linoleic acid was high in rabbit RBC membrane phospholipids. While C18:2 , C20:4 and C22:6 were the major PUFAs of human RBC membrane phospholipids studied, C18:2 and C20:4 were the major ones in the others. 22-Carbon fatty acids were present in small amounts in most species. C22:6 was present in rabbit, rat and human RBC membrane phospholipids but very little was present in dog.

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Cite This Article

DOĞRU, B., DERMİŞ, S. (2022). Gas chromatographic analysis of PS, PI, SPH and LPC Fatty acids in red blood cell membrane of rat, rabbit, human and dog. Communications Series:B Chemistry and Chemical Engineering, Cilt: 54 - Sayı: 2, 1–16. https://ajindex.com/articles/476305

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References (27)

  1. Roelofsen, B., Van Meer, G.,& Op Den Kamp, J.A.F., Scand.J.Clin.Lab.Invest.,156: (1981), 111-117
  2. Mikirova N., Riordan H. D., Jackson J. A., Wong K., Miranda-Massari J. R., Gonzalez M. J., P. R. Health Sci. J., 23(2):(2004),107-113
  3. Van den Boom, M.A.P., Groot wassink M., Roelefsen, B., de Fouw N.J. & Op den Kamp, j.A.F., Lipids, 31:(1996), 285-293
  4. Rao, C.V., Zang, E. & Reddy, B.S., Lipids 28:(1993), 441-447
  5. Folsom, A.R., Ma, J., Eckfeldt, J.H., Shahar, E. & Wu, K.K., Atherosclerosis III, (1994), 199-207
  6. Giron, M.D., Mataix, F.J., & Suarez, M.D.,Comp. Biochem. Physiol. 1002 A (1) (1992), 197-201
  7. Holub, B.J. & Kuksis, A., Adv. Lipid Res., 16:(1978), 1-125
  8. Nakagawa, Y. & Waku, K, Prog. Lipid Res., 28:(1989), 205-243
  9. Mac Donald, J.I.S. & Sprecher, H., Biochim. Biophys. Acta., 1084:(1991), 105-121
  10. Saikh, S. R. and Edidin M., Am. J. Clin. Nutr., 84(6):(2006),1277- 1289
  11. Kinsella, J.E, JPEN 14(Suppl 2) (1990), 200S-218S
  12. Spector, A.A. and Yorek, M.A., J.Lipid Res.,26: (1985), 1015-1035
  13. Barret, K.E. & Bigby, T.D., News in physiol. Sci., 10; (1995), 153-159
  14. Lewis, R. A. and Austen K.F., J. Clin. Invest., 73:(1984), 889-897
  15. De Lorgeril, M. and Salen, P., J. Cardiovasc. Med (Hagerstown), 8: (2007), 38- 41
  16. Sijben, J.W. and Calder, P.C., Proc. Nutr. Soc., 66: (2007), 237-259
  17. Tziomalos, K., Athyros, V.G., Mikhailidis, D.P., Curr. Med. Chem., 14;(2007), 2622-2628
  18. Marchioli, R., Levantesi, G., Macchia, A., Maggioni, A.P. et al., J. Membr. Biol.,206; (2005), 117-128
  19. Svensson, M., Schmidt, E.B., Jorgensen, K.A., Christensen, J.H., OPAH study group, Clin. J. Am. Soc.Nephrol., 1: (2006), 780-786.[20] Goodnight, S.H., Harris, E.S., Connor, W.E. & Illingworth D.R.,Atherosclerosis 2:(1982), 87- 113
  20. Grundy, S.M. & Denke, M.A, J.Lipid Res., 31:(1990), 1149-1172
  21. Zöllner, N. & Tato, F,Clin. Invest., 70:(1992), 968-1009
  22. McKenney J. M. And Sica D., Pharmacotherapy, 27(5): (2007), 715-728
  23. Gamez R., Mazr., Arruzazabala M. L., Mendoza S. And Castano G., Drugs, 6(1):(2005),11-19
  24. M. Rabie Al-Turkmani, Steven D. Freedman and Michael Laposata, leukotrienes and essential fatty acids, 77(5–6):(2007), 309–318
  25. Christie, W.W., in High Performance Liquid Chromatography and Lipids, [1] Pergamon Press, Oxford, 133:(1987)
  26. Ghosal, J., Biswas, T., Ghosh, A., & Datta,A.G., Biochem. Med.,32: (1984), 1– 14
  27. Nelson, G.J., Schmidt, P.C., Bartolini, G.L., Kelley