Journals / Cerrahpaşa Tıp Dergisi / 1998 / Cilt: 29 - Sayı: 2

The effect of the hyperprolactinemia on semen parameters in male infertility

Erkek infertilitesinde hiperprolaktineminin semen parametreleri üzerine etkisi

Pages
95–98
Publication Date
2022-10-10
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Bromocryptine mesylate offers no additive therapeutic effect for the hyperprolactinemia in male infertility.

📌 3 Key Takeaways

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Objective & Hypothesis:Background and design.- The effect of prolactin (PRL) on spermatogenesis and semen parameters is not known well.
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Key Findings & Data:To determine the relation between hyperprolactinemia and spermatogenesis we evaluated 85 infertile patients with hyperprolactinemia.
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Conclusion & Impact:Bromocryptine mesylate offers no additive therapeutic effect for the hyperprolactinemia in male infertility.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background and design.- The effect of prolactin (PRL) on spermatogenesis and semen parameters is not known well. To determine the relation between hyperprolactinemia and spermatogenesis we evaluated 85 infertile patients with hyperprolactinemia. We analysed the serum PRL, follicle-stimulating hormone, luteinizing hormone, total testosterone levels and obtained at least two semen analyses in all cases. Results.- In patients using bromocryptine mesylate for hyperprolactinemia, serum PRL levels returned to normal levels within 4 months, but semen analyse parameters did not differ from baseline values. Conclusion.- Hyperprolactinemia has a small ef-fect on sperm density, motility and morphology. Bromocryptine mesylate offers no additive therapeutic effect for the hyperprolactinemia in male infertility.

Özet

Prolaktinin (PRL) spermatogenez ve sperm parametreleri üzerine olan etkisi henüz kesinleşmemiştir. İnfertilite olgularında hiperprolaktinemi ve ... sperrriatogenez arasındaki ilişkiyi değerlendirmek amacı ile 85 infertil ve hiperprolaktinemili hastayı araştırdık. Olgularımızın hepsinde serum PRL, folli-kül stimülan hormon, luteinizân hormon, total testosteron düzeyi, tayinleri ve en az iki semen analizi yapılmıştır. Hiperprolaktinemi saptanan olgularda bromokriptin mesilat tedavisine başlanmış ve 2-4 aylık bir sûre sonunda PRL düzeyleri normale dönmüş, ancak bu durum semen analizi parametrelerine yansımamıştır. Sonuç olarak hiperprolaktineminin sperm sayı, morfolojisi ve motilitesine etkisinin az olduğunu ve tedavisinin erkek infertilitesi tedavisinde katkısının anlamlı olmadığını saptadık.

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Cite This Article

ALICI, B., HATTAT, H., ÖZKARA, H., AKKUŞ, E., ÇİTÇİ, A. (2022). The effect of the hyperprolactinemia on semen parameters in male infertility. Cerrahpaşa Tıp Dergisi, Cilt: 29 - Sayı: 2, 95–98. https://ajindex.com/articles/473600

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