Journals / Cerrahpaşa Tıp Dergisi / 2005 / Cilt: 36 - Sayı: 1

Evaluation of the nasal hyperresponsiveness with metacholine provocation at the healthy and patients with rhinitis

Sağlıklı ve rinit'li hastalarda metakolin provokasyonu ile nazal hiperreaktivitenin değerlendirilmesi

Pages
20–25
Publication Date
2022-10-10
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Metacholine could not trigger a significant nasal reactivity increment.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Background and Design.- In the present study, metacholine power is investigated for the trigger of nasal hyperreactivity and achievement of healthy-ill selection at the 97 diseased and 20 healthy person.
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Key Findings & Data:After provocation, there was no significant difference in NAR (nasal airway resistance) measurements between control and patient groups (p>0.05).
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Conclusion & Impact:Metacholine could not trigger a significant nasal reactivity increment.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background and Design.- In the present study, metacholine power is investigated for the trigger of nasal hyperreactivity and achievement of healthy-ill selection at the 97 diseased and 20 healthy person. After provocation, there was no significant difference in NAR (nasal airway resistance) measurements between control and patient groups (p>0.05). There was a correlation between NAR measurement and score at the end of the provocation. There was no significant positive provocation level in any groups with metacholine provocation. Achievement of healthy-ill selection of the metacholine is inadequate because of that the increment of the NAR measurements was also seen at the healthy control group. Metacholine could not trigger a significant nasal reactivity increment.

Özet

Bu çalışmada 97 hasta ve 20 sağlıklı kişide metakolinin nazal hiperreaktiviteye yol açabilme ve sağlıklı-hasta ayırımı yapma bilme yetisi araştırıldı. Provokasyon sonrası kontrol ve hasta grupları arasında NAR (nasal airway resistance) değerleri anlamlı farklılık göstermedi (p>0.05). Provokasyon sonu NAR değeri ve skor arasında korelasyon bulundu. Metakolin provokasyonu hiçbir grupta anlamlı pozitif provokasyon düzeyi oluşturmadı. Metakolin NAR değerlerinde sağladığı artışı sağlıklı kontrol grubunda da oluşturduğu için hasta-sağlıklı ayırımı yapabilme gücü yetersiz kaldı. Metakolin anlamlı nazal reaktivite atışma yol açamadı.

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Cite This Article

ÇANAKÇIOĞLU, S., TAHAMİLER, R. (2022). Evaluation of the nasal hyperresponsiveness with metacholine provocation at the healthy and patients with rhinitis. Cerrahpaşa Tıp Dergisi, Cilt: 36 - Sayı: 1, 20–25. https://ajindex.com/articles/473426

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