Journals / Cerrahpaşa Medical Journal / 2020 / Cilt: 44 - Sayı: 2

The Predictive Value of Coronary Artery Disease Complexity for Adverse Clinical Events and Myocardial Injury in Patients with Acute Coronary Syndrome

Akut Koroner Sendrom Hastalarında Koroner Arter Hastalığı Kompleksliğinin Istenmeyen Klinik Olaylar ve Miyokardiyal Hasar İçin Öngördürücü Değeri

Pages
74–79
Publication Date
2022-10-12
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Clinical outcomes were reinfarction, revascularization, and cardiac death.Results: Thrombolysis in myocardial infarction and global registry of acute coronary events risk scores were significantly higher in patients with high SxS (p=0.007 and p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The complexity of coronary artery disease (CAD) poses a challenge during percutaneous coronary interventions.
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Key Findings & Data:Although it is well-defined in patients with stable ischemic heart disease, its prognostic implication and effect on myocardial injury are not demon-strated well in patients with acute coronary syndrome (ACS).Methods: We enrolled 313 patients with ACS (149 ST-elevated myocardial infarction and 164 ACS without ST elevation) in this study.
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Conclusion & Impact:Clinical outcomes were reinfarction, revascularization, and cardiac death.Results: Thrombolysis in myocardial infarction and global registry of acute coronary events risk scores were significantly higher in patients with high SxS (p=0.007 and p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The complexity of coronary artery disease (CAD) poses a challenge during percutaneous coronary interventions. Although it is well-defined in patients with stable ischemic heart disease, its prognostic implication and effect on myocardial injury are not demon-strated well in patients with acute coronary syndrome (ACS).Methods: We enrolled 313 patients with ACS (149 ST-elevated myocardial infarction and 164 ACS without ST elevation) in this study. The complexity of CAD was decided using SYNTAX score (SxS). Amount of myocardial injury was determined according to high-sensitive troponin and creatine-kinase levels. Clinical outcomes were reinfarction, revascularization, and cardiac death.Results: Thrombolysis in myocardial infarction and global registry of acute coronary events risk scores were significantly higher in patients with high SxS (p=0.007 and p

Özet

Amaç: Koroner arter hastalığının (KAH) kompleksliği perkütan koroner girişimler sırasında zorluk teşkil etmektedir. Her ne kadar stabil koroner arter hastalığında bu kompleksliğin prognoza ve miyokardiyal hasara etkisi gösterilmiş olsa da akut koroner sendrom (AKS) has-talarında bu etki açıkça tanımlanamamıştır.Yöntemler: Bu çalışmada retrospektif olarak 313 hasta dahil edildi (149 ST elevasyonlu miyokard infarktüsü ve 164 ST yükselmesiz AKS). KAH’nın kompleksliği Syntax skoru ile deüerlendirildi. Miyokardiyal hasar düzeyi yüksek duyarlıklı troponin ve kreatin-kinaz MB düzey-lerine göre karar verildi. Klinik sonlanım noktaları re-infarktüs, revaskülarizasyon ve kardiyak ölüm olarak belirlendi.Bulgular: TIMI ve Grace skorları Syntax skoru yüksek olan grupta anlamlı olarak yüksekti (p=0,007 ve p

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Cite This Article

BARMAN, H. A., KARADAĞ, B., İKİTİMUR, B., DURMAZ, E., AVCI, B. K., YURTSEVEN, E., ERTUĞRUL, S., ERTÜRK, E., KOLDAŞ, L. (2022). The Predictive Value of Coronary Artery Disease Complexity for Adverse Clinical Events and Myocardial Injury in Patients with Acute Coronary Syndrome. Cerrahpaşa Medical Journal, Cilt: 44 - Sayı: 2, 74–79. https://ajindex.com/articles/473158

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