Journals / Cerrahpaşa Medical Journal / 2021 / Cilt: 45 - Sayı: 1

The Investigation of Gastroesophageal Reflux in Children with Portal Hypertention

Portal Hipertansiyonlu Çocuklarda Gastroözofageal Reflü Araştırması

Pages
28–32
Publication Date
2022-10-12
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Because of the increased reflux ratio, all children with portal hypertension should be treated.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: To investigate the effect of the portal hypertension on gastroesophageal reflux disease in childhood.
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Key Findings & Data:Methods: A total of 30 patients with portal hypertension were included in the study.
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Conclusion & Impact:Because of the increased reflux ratio, all children with portal hypertension should be treated.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: To investigate the effect of the portal hypertension on gastroesophageal reflux disease in childhood. Methods: A total of 30 patients with portal hypertension were included in the study. The patients were divided into 3 main groups; Group I: patients without sclerotherapy, Group II: patients on the endoscopic sclerotherapy program, Group III: patients who had surgical devascularization. Gastroesophageal reflux symptoms, endoscopic findings of esophagitis and 24-hour pH monitorization were noted. The Fisher exact test was used for statistical analysis. Results: This study showed that the incidence of gastroesophageal reflux was significantly higher in all these three groups than in healthy people. There were no significant differences among the groups on the basis of the symptoms. In the endoscopic examination, reflux was found higher in groups I and III than in group II, whereas, in the 24-hour pH monitorization, no significant differences were seen among the groups. Conclusion: Portal hypertensive patients have higher incidence of gastroesophageal reflux than healthy population. Clinical signs and symptoms, endoscopic examination and pH monitorization should all be evaluated together. Because of the increased reflux ratio, all children with portal hypertension should be treated.

Özet

Amaç: Bu çalışmada, portal hipertansiyonlu çocuk hastalarda, portal hipertansiyon ve tedavi edici girişimlerin gastroözofageal reflühastalığı ile ilişkisini araştırmak hedeflendi.Gereç ve Yöntemler: Çalışmaya 30 portal hipertansiyonlu çocuk hasta alındı. Hastalar üç ana gruba ayrıldı;Grup 1: Endoskopik skleroterapi uygulanmamış olgular.Grup 2: Endoskopik skleroterapi programında olan olgular.Grup 3: Devaskülarizasyon ameliyatı yapılan olgular.Hastaların gastroözofageal reflü şikayetleri, endoskopi ve 24 saatlik pH monitorizasyonu bulguları kaydedildi. İstatistiksel inceleme Fisher-Exact yöntemi ile yapıldı.Bulgular: Çalışmada portal hipertansiyonlu olgularda, üç incelemede de, gastroözofageal reflü toplumdakine oranla belirgin olarak fazlagörüldü. Klinik reflü göz önüne alındığında gruplar arasında anlamlı fark bulunmadı. Endoskopi bulguları göz önüne alındığında Grup 1 ve3’te Grup 2’ye göre anlamlı olarak fazla saptandı. Buna karşılık 24 saatlik pH metre incelemelerinde, gruplar arası anlamlı fark bulunmadı.Sonuç: Portal hipertansif olgulardaki gastroözofageal reflü araştırmasında tek bir yöntem yeterli değildir. Klinik belirti ve bulgular, endoskopik muayene ve pH monitorizasyonu birlikte değerlendirilmelidir. Yüksek reflü oranı nedeni ile tüm portal hipertansif çocuklarıntedavi altına alınması akılcı bir yaklaşım olarak görülmektedir.

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Cite This Article

Şenyüz, O. F., Önal, Z., Eliçevik, M., Alim, E. R., Can, G., Alim, A. (2022). The Investigation of Gastroesophageal Reflux in Children with Portal Hypertention. Cerrahpaşa Medical Journal, Cilt: 45 - Sayı: 1, 28–32. https://ajindex.com/articles/473121

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