Journals / Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi / 2022 / Cilt: 9 - Sayı: 2

Effects of Dietary Polyphenols on Browning and Brown Adipose Tissue Activity

Diyet Polifenollerinin Kahverengileşme ve Kahverengi Yağ Dokusu Aktivitesi Üzerine Etkileri

Pages
334–340
Publication Date
2022-10-12
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This review assesses the possible effects of some polyphenols on the regulation of energy expenditure through browning.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The World Health Organization (WHO) states that about 13% of the world’s adult population is obese.
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Key Findings & Data:This makes obesity and its complications one of the most important global public health concerns and preventable diseases.
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Conclusion & Impact:This review assesses the possible effects of some polyphenols on the regulation of energy expenditure through browning.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Kahverengi yağ dokusu · beyaz yağ dokusu · kahverengileşme

Abstract

The World Health Organization (WHO) states that about 13% of the world’s adult population is obese. This makes obesity and its complications one of the most important global public health concerns and preventable diseases. Nutrition has a key role in the prevention and management of obesity. Many studies show that food-derived elements (especially polyphenols) may play a role in the prevention and management of obesity. The determination of the presence of active brown adipose tissue in people and the expenditure of energy through the activation of brown adipose tissue (BAT) is shown as a promising method in the management of obesity. It is believed that some anti-diabetic and obesity-preventing activities associated with polyphenols may have a positive effect on energy expenditure. This review assesses the possible effects of some polyphenols on the regulation of energy expenditure through browning.

Özet

Dünya Sağlık Örgütü (DSÖ) dünya yetişkin nüfusunun yaklaşık %13'ünün obez olduğunu belirtmektedir. Bu durum obeziteyi ve komplikasyonlarını, en önemli küresel halk sağlığı endişelerinden ve önlenebilir hastalıklardan biri haline getirmektedir. Beslenme, obezitenin önlenmesinde ve yönetiminde kilit role sahiptir. Birçok çalışma, besin kaynaklı ögelerin (özellikle polifenollerin) obezitenin önlenmesinde ve yönetiminde rol oynayabileceğini göstermektedir. Yetişkin insanlarda aktif kahverengi yağ dokusu varlığının tespiti ve kahverengi yağ dokusunun (KYD) aktivasyonu yoluyla enerji harcaması, obezite yönetiminde umut verici bir yöntem olarak gösterilmektedir. Polifenollerle ilişkilendirilen bazı anti-diyabetik ve obeziteyi önlemeye yönelik aktivitelerin, enerji harcaması üzerinde olumlu etkileri olabileceği düşünülmektedir. Bu derleme enerji harcamasının kahverengileşme yoluyla düzenlenmesinde bazı polifenollerin olası etkilerini değerlendirmektedir.

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Cite This Article

ÇINAR, E. N., İLHAN, A., METİN, M. M. T. (2022). Effects of Dietary Polyphenols on Browning and Brown Adipose Tissue Activity. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, Cilt: 9 - Sayı: 2, 334–340. https://ajindex.com/articles/472581

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References (15)

  1. Montanari, T, Pošćić, N, Colitti, M, Factors involved in white‐to‐brown adipose tissue conversion and in thermogenesis: a review. Obesity Reviews, 2017. 18(5): p. 495-513
  2. Silvester, A.J, Aseer, K.R, Yun, J.M, Dietary polyphenols and their roles in fat browning. The Journal of Nutritional Biochemistry, 2019. 64: p. 1-12
  3. Poher, A.-L., Altirriba, J., Veyrat-Durubex, C., Rohner-Jeanrenaud, F, Brown adipose tissue activity as a target for the treatment of obesity/insulin resistance. Frontiers in Physiology, 2015. 6: p. 4
  4. Li, Z, Zhang, Z, Ke, L, Sun, Y, Li, Wenxue, Feng, X, Zhu, W, Chen, S, Resveratrol promotes white adipocytes browning and improves metabolic disorders in Sirt1‐dependent manner in mice. The FASEB Journal, 2020. 34(3): p. 4527-4539
  5. Mele, L, Bidault, G, Mena, P, Crozier, A, Brighenti, F, Vidal-Puig, A, Del Rio, D, Dietary (Poly)phenols, Brown Adipose Tissue Activation, and Energy Expenditure: A Narrative Review. Adv Nutr, 2017. 8(5): p. 694-704
  6. Marlatt, K.L, and Ravussin, E, Brown Adipose Tissue: an Update on Recent Findings. Current Obesity Report, 2017. 6(4): p. 389-396
  7. Hu, X., Zhang, Y, Xue, Y, Zhang, Z, Wang, J, Berberine is a potential therapeutic agent for metabolic syndrome via brown adipose tissue activation and metabolism regulation. American Journal of Translational Research, 2018. 10(11): p. 3322
  8. Okla, M, Kim, J, Koehler, K, Chung, S, Dietary factors promoting brown and beige fat development and thermogenesis. Advances in Nutrition, 2017. 8(3): p. 473-483
  9. Concha, F, Prado, G, ve ark. Nutritional and non-nutritional agents that stimulate white adipose tissue browning. Reviews in Endocrine and Metabolic Disorders, 2019. 20(2): p. 161-171
  10. Betz, M.J, and Enerbäck, S, Human brown adipose tissue: what we have learned so far. Diabetes, 2015. 64(7): p. 2352-2360
  11. Villarroya, F, Cereijo, R, Villarroya, J, Giralt, M, Brown adipose tissue as a secretory organ. Nature Reviews Endocrinology, 2017. 13(1): p. 26-35
  12. Arhire, L.I, Mihalache, L, Covasa, M, Irisin: a hope in understanding and managing obesity and metabolic syndrome. Frontiers in Endocrinology, 2019. 10: p. 524
  13. Oelkrug, R, Polymeropoulos, E, Jastroch, M, Brown adipose tissue: physiological function and evolutionary significance. Journal of Comparative Physiology B, 2015. 185(6): p. 587-606
  14. Luo, L, and Liu, M, Adipose tissue in control of metabolism. Journal of Endocrinology, 2016. 231(3): p. R77-R99
  15. Kaisanlahti, A, and Glumoff,