Journals / Cukurova Medical Journal / 2018 / Cilt: 43 - Sayı: 1

Comparison of lidocaine-lidocaine and lidocaine-esmolol efficiency in control of haemodynamic response to endotracheal extubation craniotomies

Kraniyotomilerde endotrakeal ekstübasyona bağlı gelişen hemodinamik yanıtın kontrolünde lidokain-lidokain ve lidokain - esmolol etkinliğinin karşılaştırılması

Pages
91–98
Publication Date
2018-03-31
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Extubation, eye opening, verbal response and orientation time in Group II were significantly longer than in Group I.Conclusion: Lidocaine bolus- lidocaine infusion which administered before extubation provided more stable hemodynamics and shorter extubation time than lidocaine bolus-esmolol infusion in patients who undergoing craniotomy.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: In this study, we aimed to compare efficiency of lidocaine+lidocaine and lidocaine+esmolol combinations on elimination of undesirable hemodynamic changes during extubation.Materials and Methods: 60 patients ASA I-III scheduled for craniotomy were included in this study.
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Key Findings & Data:Anaesthesia maintenance was provided with sevoflurane-remifentanil and 2 mg kg -1 tramadol for postoperative pain.
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Conclusion & Impact:Extubation, eye opening, verbal response and orientation time in Group II were significantly longer than in Group I.Conclusion: Lidocaine bolus- lidocaine infusion which administered before extubation provided more stable hemodynamics and shorter extubation time than lidocaine bolus-esmolol infusion in patients who undergoing craniotomy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Lidokain · esmolol · ekstübasyon

Abstract

Purpose: In this study, we aimed to compare efficiency of lidocaine+lidocaine and lidocaine+esmolol combinations on elimination of undesirable hemodynamic changes during extubation.Materials and Methods: 60 patients ASA I-III scheduled for craniotomy were included in this study. Anaesthesia maintenance was provided with sevoflurane-remifentanil and 2 mg kg -1 tramadol for postoperative pain. Lidocaine İV bolus 1 mg kg-1 was administered to the patients 10 minutes before the end of operation in both groups. Lidocaine İV infusion 0.025 mg kg h-1 and Esmolol İV infusion 50 mcg kg min-1 was administered to Group I (Lidocain+Lidocain) and II (Lidocain+Esmolol) respectively. Haemodynamic parameters were recorded at 1, 5 and 10 minutes after lidokain and esmolol infusions. Results: There was a statistically significiant increase for haemodynamic changes after extubation when compared preoperative period in group I. There was a statistically significant increase for haemodynamic changes at 10 minutes after esmolol administration and extubation when compared preoperative period in group II. Extubation, eye opening, verbal response and orientation time in Group II were significantly longer than in Group I.Conclusion: Lidocaine bolus- lidocaine infusion which administered before extubation provided more stable hemodynamics and shorter extubation time than lidocaine bolus-esmolol infusion in patients who undergoing craniotomy.

Özet

Amaç: Kraniyotomi operasyonlarında ekstübasyon sırasında gelişebilecek istenmeyen hemodinamik değişiklikleri ortadan kaldırmak için, çalışmamızda lidokain+lidokain, lidokain+esmolol etkisini karşılaştırmayı amaçladık.Gereç ve Yöntem: Kraniyotomi uygulanacak ASA I-III grubu 60 hasta çalışmaya dahil edildi. Anestezi idamesi ise sevofluran-remifentanil kombinasyonu ile sağlandı. Postoperatif analjezi 2 mg kg-1 intravenöz tramadol ile sağlandı. Ameliyat bitimine 10 dakika kala hemodinamik parametreler kaydedildikten sonra tüm hastalara 1mg kg-1 bolus lidokain intravenöz yapıldı. Hastalar rastgele iki gruba ayrılarak Grup I’ de (grup Lidokain+Lidokain) 0,025mg kg sa-1 lidokain, Grup II’ de (grup Lidokain+Esmolol) 50 µg kg dk-1 esmolol infüzyonu başlandı. Hastaların lidokain ve esmolol infüzyonları sonrası 1.-5. ve 10. dakikada, hemodinamik parametreleri kaydedildi. Bulgular: Grup I’ de preoperatif döneme göre ekstübasyon sonrasında hemodinamik değişikliklerde anlamlı artış gözlendi. Grup II’ de esmolol infüzyonu sonrası 10. dakika ve ekstübasyon sonrasındaki hemodinamik değişikliklerde preoperatif döneme göre anlamlı artış belirlendi. Grup II’ de ekstübasyon zamanı, göz açma, sözel yanıt, oryantasyon süresi grup I’ den anlamlı olarak daha yüksekti.Sonuç: Kraniyotomi uygulanan olgularda ekstübasyon öncesinde uygulanan lidokain+lidokain infüzyonunun lidokain+esmolol infüzyonuna göre ekstübasyon sırası ve sonrasında daha stabil bir hemodinami sağladığı, ekstübasyon süresinin daha kısa olduğu kanısına varıldı.

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Cite This Article

SÜMER, E., BİRİCİK, E., GÜNEŞ, Y., GÜNDÜZ, M., ILGINEL, M. (2018). Comparison of lidocaine-lidocaine and lidocaine-esmolol efficiency in control of haemodynamic response to endotracheal extubation craniotomies. Cukurova Medical Journal, Cilt: 43 - Sayı: 1, 91–98. https://ajindex.com/articles/46719

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