SavedAdd your journal

Journals / Bitlis Eren Üniversitesi Fen Bilimleri Dergisi / 2019 / Cilt: 8 - Sayı: 2

Hydroxyl Radical and Hypochlorous Acid Scavenging Activity of Mentha longifolia (L.) Hudson subsp. typhoides (Briq.) Harley var. typhoides

Mentha longifolia (L.) Hudson subsp. typhoides (Briq.) Harley var.typhoides’in Hidroksil Radikali ve Hipokloröz Asit Süpürme Aktiviteleri

Ferda CANDAN
Mahire BAYRAMOĞLU AKKOYUN
Pages
406–412
Publication Date
2022-10-12
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It is also thought that it may have high effect as therapeutic agents in the protection or treatment of many diseases due to oxidative stres.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The purpose of this study was to investigate the antioxidant potential with hydroxyl radical(OH. ) and hypochlorous acid(HOCI) scavenging activity of the ethanol extract of Mentha longifolia (L.) Hudson subsp. typhoides (Briq.) Harley var. typhoides.
📊
Key Findings & Data:The total antioxidant activity was found to be 569 ± 8.57 mg AAE/gr of extract.
💡
Conclusion & Impact:It is also thought that it may have high effect as therapeutic agents in the protection or treatment of many diseases due to oxidative stres.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The purpose of this study was to investigate the antioxidant potential with hydroxyl radical(OH. ) and hypochlorous acid(HOCI) scavenging activity of the ethanol extract of Mentha longifolia (L.) Hudson subsp. typhoides (Briq.) Harley var. typhoides. The total antioxidant activity was found to be 569 ± 8.57 mg AAE/gr of extract. Mentha longifolia (L.) Hudson subsp. typhoides (Briq.) Harley. IC50 values of typhoides ethanol extract, hydroxyl radical and hypochlorous acid were determined as 75.09±2.47 and 201.43±17.99 µg/mL respectively. As a result, the total antioxidant capacity and radical scavenging activity of the plant ethanol extract can be considered as a potential natural antioxidant source of the plant. It is also thought that it may have high effect as therapeutic agents in the protection or treatment of many diseases due to oxidative stres.

Özet

Çalışmada Mentha longifolia (L.) Hudson subsp. typhoides (Briq.) Harley var. typhoides etanol ekstraktının totalantioksidan kapasitesi ile hidroksil radikali (OH.) ve hipokloröz asit(HOCI) süpürme aktivitesinindeğerlendirilmesi amaçlandı. M. longifolia subsp. typhoides var. typhoides total antioksidan kapasitesi 569±8.57mg AAE/gr olarak belirlendi. Mentha longifolia (L.) Hudson subsp. typhoides (Briq.) Harley var. typhoides etanolekstraktının, hidroksil radikali ve hipokloröz asit süpürücü aktiviteleri incelendiğinde IC50 değerleri ise sırasıyla75.09±2.47 ve 201.43±17.99 µg/mL olarak tesbit edildi. Sonuç olarak M. longifolia subsp. typhoides var. typhoidesetanol ekstraktının total antioksidan kapasitesi ve radikal süpürme aktivitesi değerlendirildiğinde bitkininpotensiyel bir doğal antioksidan kaynağı olabileceği söylenebilir. Ayrıca, oksidatif strese bağlı olarak ortayaçıkabilecek birçok hastalığın önlenmesi veya tedavisinde terapötik ajanlar olarak yüksek etkiye sahip olabileceğidüşünülmektedir.

🔖

Cite This Article

CANDAN, F., AKKOYUN, M. B. (2022). Hydroxyl Radical and Hypochlorous Acid Scavenging Activity of Mentha longifolia (L.) Hudson subsp. typhoides (Briq.) Harley var. typhoides. Bitlis Eren Üniversitesi Fen Bilimleri Dergisi, Cilt: 8 - Sayı: 2, 406–412. https://ajindex.com/articles/467111

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Özgen U., Mavi A., Terzi Z., Yιldιrιm A., Coşkun M., Houghton P.J. 2006. Antioxidant properties of some medicinal Lamiaceae (Labiatae) species. Pharmaceutical biology, 44 (2): 107- 112
  2. Birben E., Sahiner U.M., Sackesen C., Erzurum S., Kalayci O. 2012. Oxidative stress and antioxidant defense. World Allergy Organization Journal, 5 (1): 9
  3. Kasprzak K.S. 2002. Oxidative DNA and protein damage in metal-induced toxicity and carcinogenesis1, 3. Free Radical Biology and Medicine, 32 (10): 958-967
  4. Iwasaki A., Gagnon C. 1992. Formation of reactive oxygen species in spermatozoa of infertile patients. Fertility and sterility, 57 (2): 409-416
  5. Letelier M.E., Molina-Berríos A., Cortés-Troncoso J., Jara-Sandoval J., Holst M., Palma K., González-Lira V. 2008. DPPH and oxygen free radicals as pro-oxidant of biomolecules. Toxicology in vitro, 22 (2): 279-286
  6. Alscher R.G., Donahue J.L., Cramer C.L. 1997. Reactive oxygen species and antioxidants: relationships in green cells. Physiologia Plantarum, 100 (2): 224-233
  7. Sevindik M., Akgul H., Pehlivan M., Selamoglu Z. 2017. Determination of therapeutic potential of Mentha longifolia ssp. longifolia. Fresen Environ Bull, 26, 4757-4763
  8. Mikaili P., Mojaverrostami S., Moloudizargari M., Aghajanshakeri S. 2013. Pharmacological and therapeutic effects of Mentha longifolia L. and its main constituent, menthol. Ancient science of life, 33 (2): 131
  9. Mimica-Dukic N., Popovic M., Jakovljevic V., Szabo A., Gašic O. 1999. Pharmacological studies of Mentha longifolia phenolic extracts. II. Hepatoprotective activity. Pharmaceutical biology, 37 (3): 221-224
  10. Bandar H., Hijazi A., Rammal H., Hachem A., Saad Z., Badran B. 2013. Techniques for the extraction of bioactive compounds from Lebanese Urtica Dioica. American Journal of Phytomedicine and Clinical Therapeutics, 1 (6): 507-513
  11. Prieto P, Pineda M, Aguilar M. 1999. Spectrophotometric quantitation of antioxidant capacity through the formation of a phosphomolybdenum complex: specific application to the determination of vitamin E. Anal Biochem, 269: 337-341
  12. Kunchandy E., Rao M.N.A. 1990. Oxygen radical scavenging activity of curcumin. Int. J. Pharmacog, 58: 237-240
  13. Aruoma OI, Halliwell B. 1987. Action of hypochlorous acid on the antioxidant protective enzymes superoxide dismutase, catalase and glutathione peroxidase. Biochem J 248: 973– 97
  14. Pedraza‐Chaverrí J., Arriaga‐Noblecía G., Medina‐Campos O.N. 2007. Hypochlorous acid scav