Journals / Bezmiâlem Science / 2018 / Cilt: 6 - Sayı: 1

Comparison between Risk Factors for Candidemia and Bacteremia in a Tertiary Intensive Care Unit

Bir Üçüncü Basamak Yoğun Bakım Ünitesinde Kandidemi ve Bakteremi Arasındaki Risk Faktörlerinin Karşılaştırılması

Pages
9–14
Publication Date
2022-10-12
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

According to the results of our study, previous GIS surgery, hav- ing a surgical implement, solid organ tumor, end-stage renal dis- ease, need for blood transfusion, and TPN were found to be risk factors of candidemia.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Candidemia is the most common type of invasive fungal infections.
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Key Findings & Data:In this study, we aimed to compare the potential risk factors of candidemia and aerobic bacteremia.Methods: In this study, 21 patients with candidemia and 101 patients with bacteremia were retrospectively compared with 1567 patients who were admitted to a tertiary intensive care unit between January 2011 and January 2014.
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Conclusion & Impact:According to the results of our study, previous GIS surgery, hav- ing a surgical implement, solid organ tumor, end-stage renal dis- ease, need for blood transfusion, and TPN were found to be risk factors of candidemia.
🔬Design:Research Article
📍Scope:2011 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: Candidemia is the most common type of invasive fungal infections. It is essential to initiate early and appropriate treatment. In this study, we aimed to compare the potential risk factors of candidemia and aerobic bacteremia.Methods: In this study, 21 patients with candidemia and 101 patients with bacteremia were retrospectively compared with 1567 patients who were admitted to a tertiary intensive care unit between January 2011 and January 2014. Potential risk factors for the patients were evaluated statistically.Results: fte rate and incidence density of candidemia were, re- spectively, 1.34% and 1.62, whereas those for bacteremia were 9.38% and 11.37, respectively. According to our results, having a previous gastrointestinal system (GIS) surgery, solid organ tu- mor (p=0.0001), hemodialysis catheter (p=0.001), continuous hemodiafiltration (p=0.005), bogota bag (p=0.009), colostomy (p=0.033), abdominal drain (p=0.001), need for blood transfu- sion (p=0.025), and total parenteral nutrition (TPN) (p=0.0001) were found to be associated risk factors for candidemia in com- parison with bacteremia.Conclusion: Patients who have blood stream infections have higher risk for morbidity and mortality in intensive care units. According to the results of our study, previous GIS surgery, hav- ing a surgical implement, solid organ tumor, end-stage renal dis- ease, need for blood transfusion, and TPN were found to be risk factors of candidemia.

Özet

Amaç: Kandidemi en yaygın invazif fungal enfeksiyondur (İFE). Mortalite oranlarını arttırdığı için, kan dolaşım enfeksiyonlarını ve sorumlu ajanları tespit etmek ve erken uygun tedaviye başla- mak esastır. Bu çalışmada, kandidemi ve aerobik bakteremi için potansiyel risk faktörlerini karşılaştırmayı amaçladık. Yöntemler: Ocak 2011 ile Ocak 2014 tarihleri arasında bir üçüncü basamak yoğun bakım ünitesine kabul edilen 1567 hasta arasından, Kandidemili 21 hasta ve 101 bakteremik hasta ret- rospektif olarak karşılaştırıldı. Kandolaşımı enfeksiyonu tanısı CDC kılavuzuna göre yapıldı. Hastalar için, potansiyel risk fak- törleri NCCS (Number Crunch Statistical System) istatistiksel sistemi ile değerlendirildi. İki grubu karşılaştırmak için bağımsız T-Test kullanıldı, sayısal veri Chi Square test ve Fisher’s exact test ile karşılaştırıldı. Bulgular: Kandidemi oranı ve insidans dansitesi sırasıyla %1,34 ve 1,62 iken, bakteremi oranları sırasıyla %9,38 ve 11,37 bulun- du. Sonuçlara göre; öncesinde gastrointestinal (GİS) cerrahi ge- çirmiş olmak (p=0,001), solid organ tümörü (p=0,0001), hemo- diyaliz kateteri (p=0,001), sürekli hemodiafiltrasyon (p=0,005), Bogoto Bag (p=0,009), kolostomi (p=0,033), abdominal dren (p=0,001), kan transfüzyon ihtiyacı ve total parenteral beslenme (TPB) (p=0,0001), bakteremi ile karşılaştırıldığında daha çok kandidemi lehine anlamlı risk olarak bulundu. Sonuç: Yoğun bakım ünitesinde kandolaşımı enfeksiyonu olan hastalar, mortalite ve morbidite için yüksek risk taşırlar. Sonuç- lara göre; öncesinde GİS cerrahisi geçirmiş olmak, cerrahi imple- mentasyon varlığı, solid organ tümörü, son dönem böbrek hasta- lığı, kan transfüzyon ihtiyacı ve TPB kandidemi için risk faktörü olarak bulunmuştur.

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Cite This Article

DURDU, B., DURDU, Y., HAKYEMEZ, İ. N., EREN, G., GÜLEÇ, N., KARTYAŞAR, H. K. (2022). Comparison between Risk Factors for Candidemia and Bacteremia in a Tertiary Intensive Care Unit. Bezmiâlem Science, Cilt: 6 - Sayı: 1, 9–14. https://ajindex.com/articles/464132

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