Journals / Bezmiâlem Science / 2020 / Cilt: 8 - Sayı: 2

Evaluation of Clinical Features and Prognosis in COVID-19Patients with Hypertension: A Single-center RetrospectiveObservational Study

Hipertansiyonu Olan COVİD-19 Hastalarında Klinik Özelliklerin ve Prognozun Değerlendirilmesi: Tek Merkezli Retrospektif Gözlemsel Çalışma

Pages
15–21
Publication Date
2022-10-12
DOI
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Hypertensive patients were older (64.6±11.5 and 47.2±13.9) (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The aim of this study is to investigate the effect of hypertension on the clinical severity and prognosis of Coronavirus disease-2019 (COVID-19) patients.Methods: In this retrospective observational study, reverse transcription-polymerase chain reaction (RT-PCR) positive COVID-19 patients over the age of 18 years who were hospitalized in Bezmialem Vakıf University between March and May 2020 were included.
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Key Findings & Data:The patients were divided into two groups as hypertensive and non-hypertensive and compared for clinical, laboratory and prognosis.Results: Two hundred sixty COVID-19 patients were included in the study, 55.4% of them were male and the mean (± standard deviation) age was 54.1±15.5 years.
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Conclusion & Impact:Hypertensive patients were older (64.6±11.5 and 47.2±13.9) (p
🔬Design:Research Article
📍Scope:2019 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: The aim of this study is to investigate the effect of hypertension on the clinical severity and prognosis of Coronavirus disease-2019 (COVID-19) patients.Methods: In this retrospective observational study, reverse transcription-polymerase chain reaction (RT-PCR) positive COVID-19 patients over the age of 18 years who were hospitalized in Bezmialem Vakıf University between March and May 2020 were included. The patients were divided into two groups as hypertensive and non-hypertensive and compared for clinical, laboratory and prognosis.Results: Two hundred sixty COVID-19 patients were included in the study, 55.4% of them were male and the mean (± standard deviation) age was 54.1±15.5 years. Hypertensive patients were older (64.6±11.5 and 47.2±13.9) (p

Özet

Amaç: Bu çalışmada amacımız, hipertansiyonun Koronavirüshastalığı-2019 (COVİD-19) hastalarının klinik ağırlığı ve prognozuüzerine etkisini araştırmaktır.Yöntemler: Bu retrospektif gözlemsel çalışmaya Mart-Mayıs 2020tarihleri arasında Bezmialem Vakıf Üniversitesi Hastanesi’ndeyatarak izlenen 18 yaş üstü, ters transkripsiyon-polimeraz zincirreaksiyonu (RT-PCR) pozitif COVİD-19 hastalar dahil edildi.Hastalar hipertansif ve hipertansif olmayan olarak iki gruba ayrılarakklinik, laboratuvar ve prognoz açısından karşılaştırıldı.Bulgular: Çalışmaya dahil edilen 260 COVİD-19 hastasının%55,4’ü erkek, yaş ortalamaları (± standart sapma) 54,1±15,5’tir.Hipertansif hastalar daha yaşlıydı (64,6±11,5 ve 47,2±13,9)(p

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Cite This Article

KAÇMAZ, A. B., KOÇ, M. M., SÜMBÜL, B., OKAY, G., DURDU, B., AKKOYUNLU, Y., BÖLÜKÇÜ, S., KARAKUŞ, H. D. (2022). Evaluation of Clinical Features and Prognosis in COVID-19Patients with Hypertension: A Single-center RetrospectiveObservational Study. Bezmiâlem Science, Cilt: 8 - Sayı: 2, 15–21. https://ajindex.com/articles/464082

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References (13)

  1. Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395:1054-62
  2. World Health Organization. Coronavirus disease (COVID-19). Situation report 142. June 2020 [June 2020]. Available from:
  3. Wu C, Chen X, Cai Y, Xia J, Zhou X, Xu S, et al. Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China. JAMA Intern Med 2020;180:934-43
  4. Wu JT, Leung K, Bushman M, Kishore N, Niehus R, de Salazar PM, et al. Estimating clinical severity of COVID-19 from the transmission dynamics in Wuhan, China. Nat Med 2020;26:506-10
  5. Zhou P, Yang XL, Wang XG, Hu B, Zhang L, Zhang W, et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature 2020;579:270-3
  6. Lu R, Zhao X, Li J, Niu P, Yang B, Wu H, et al. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet 2020;395:565-74
  7. Hamming I, Timens W, Bulthuis ML, Lely AT, Navis G, van Goor H. Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis. J Pathol 2004;203:631-7
  8. Jia HP, Look DC, Shi L, Hickey M, Pewe L, Netland J, et al. ACE2 receptor expression and severe acute respiratory syndrome coronavirus infection depend on differentiation of human airway epithelia. J Virol 2005;791:14614-21
  9. Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-ınfected pneumonia in Wuhan, China. JAMA 2020;323:1061-9
  10. Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med 2020;382:1708-20
  11. Yan R, Zhang Y, Li Y, Xia L, Guo Y, Zhou Q. Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2. Science 2020;367:1444-8
  12. Altun B, Arici M, Nergizoglu G, Derici Ü, Karatan O, Turgan Ç, et al. Prevalence, awareness, treatment and control of hypertension in Turkey (the PatenT study) in 2003. J Hypertension 2005;23:1817- 23
  13. Huang S, Wang J, Liu F, Liu J, Cao G, Yang C, et al. COVID-19 patients with hypertension have more severe disease: a