Journals / Bezmiâlem Science / 2021 / Cilt: 9 - Sayı: 1

Clinical Course of COVID-19 in a Thalassemia Major Patient who Underwent Haematopoietic Stem Cell Transplantation

Hematopoetik Kök Hücre Nakli Yapılmış Bir Talasemi Majör Hastasında COVID- 19’un Klinik Seyri

Pages
91–93
Publication Date
2022-10-12
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this casereport, we wanted to point out that the course of the COVID-19 isunexpectedly mild in such a patient with thalassemia major.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:We herein reported the course of Coronavirus diasease-19(COVID-19) in a 21-year-old patient with thalassemia majordisease.
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Key Findings & Data:The patient who underwent haematopoietic stem celltransplantation in 2013 and developed alloimmunization, presentedwith high fever and weakness.
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Conclusion & Impact:In this casereport, we wanted to point out that the course of the COVID-19 isunexpectedly mild in such a patient with thalassemia major.
🔬Design:Research Article
📍Scope:2013 Verileri
⚙️Variables:Domain Parameters

Abstract

We herein reported the course of Coronavirus diasease-19(COVID-19) in a 21-year-old patient with thalassemia majordisease. The patient who underwent haematopoietic stem celltransplantation in 2013 and developed alloimmunization, presentedwith high fever and weakness. His parents have been recentlydiagnosed with COVID-19. COVID-19 diagnosis was confirmedby real time-polymerase chain reaction (RT-PCR) method inthe nasopharyngeal swab sample of the patient while his thoraxcomputed tomography was not found in favor of pneumonia.The patient was treated with hydroxychloroquine 2x200mg andFavipravir 3x600mg. The temperature fell with in three days. Theclinical condition of the patient improved rapidly. On the 20thday, he did not have any symptom with a recovery of anemia andlymphopenia, but the RT-PCR result was stil positive. In this casereport, we wanted to point out that the course of the COVID-19 isunexpectedly mild in such a patient with thalassemia major.

Özet

Talasemi major hastalığı olan 21 yaşındaki bir hastada Koronavirüs hastalığı-19’un (COVİD-19) klinik seyri sunulmuştur. 2013 yılında hematopoetik kök hücre nakli yapılmış ve alloimmunizasyon gelişmiş hasta, yüksek ateş ve halsizlik şikayeti ile başvurdu. Yakın zamanda anne ve babası COVİD-19 tanısı almıştı. Toraks tomografisinde pnömoni lehine bulgu saptanmayan hastanın COVİD-19 tanısı nazofarengeal sürüntü örneğinde gerçek zamanlı polimeraz zincir reaksiyonu (RT-PCR) yöntemiyle doğrulandı. Hastaya hidroksiklorokin 2x200 mg ve favipravir 3x600 mg tedavisi başlandı. Ateşi üç gün sonra düştü. Hastanın klinik durumu hızla iyileşti. Anemi ve lenfopenisi düzelen hastanın, tedavinin 20. gününde herhangi bir semptomu yoktu. Ancak RT-PCR sonucu hala pozitif idi. Bu olgu sunumuyla talasemi majörü olan bir hastada, COVID-19’un beklenmedik biçimde hafif seyrettiğine dikkati çekmek istedik.

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Cite This Article

AKTAŞ, H., HAMİDİ, A. A., ULU, Y. (2022). Clinical Course of COVID-19 in a Thalassemia Major Patient who Underwent Haematopoietic Stem Cell Transplantation. Bezmiâlem Science, Cilt: 9 - Sayı: 1, 91–93. https://ajindex.com/articles/463998

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