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Journals / Balkan Medical Journal / 2013 / Cilt: 30 - Sayı: 2

Balanced chromosomal translocation of chromosomes 6 and 7: A rare male factor of spontaneous abortions

Ateş KADIOĞLU
Sefa RESİM
Erkan EFE
Tolga AKMAN
Ayşe Gül BAYRAK
Pages
250–252
Publication Date
2022-10-11
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The possibility of spontaneous abortions can be reduced with preimplantation genetic diagnosis (PGD) before embryo transfer.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Background: Carriers of structural chromosomal rearrangements such as Robertsonian or reciprocal translocations have an increased risk of spontaneous abortion and producing offspring with genetic abnormalities.
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Key Findings & Data:Case Report: We report a man with balanced chromosomal translocations located at 6p22, and 7q22.
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Conclusion & Impact:The possibility of spontaneous abortions can be reduced with preimplantation genetic diagnosis (PGD) before embryo transfer.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background: Carriers of structural chromosomal rearrangements such as Robertsonian or reciprocal translocations have an increased risk of spontaneous abortion and producing offspring with genetic abnormalities. Case Report: We report a man with balanced chromosomal translocations located at 6p22, and 7q22. His wife has a history of four spontaneous abortions. Conclusion: Couples with a history of abortions should be investigated cytogenetically, after other causes of miscarriages are excluded. The possibility of spontaneous abortions can be reduced with preimplantation genetic diagnosis (PGD) before embryo transfer.

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Cite This Article

KADIOĞLU, A., RESİM, S., EFE, E., AKMAN, T., BAYRAK, A. G. (2022). Balanced chromosomal translocation of chromosomes 6 and 7: A rare male factor of spontaneous abortions. Balkan Medical Journal, Cilt: 30 - Sayı: 2, 250–252. https://ajindex.com/articles/461551

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