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Journals / Balkan Medical Journal / 2019 / Cilt: 36 - Sayı: 5

Regular Aerobic Voluntary Exercise Increased Oxytocin in Female Mice: The Cause of Decreased Anxiety and Increased Empathy-Like Behaviors

Oğuz YÜKSEL
Nazan UYSAL
Zeynep YÜCE
Başar KOÇ
Aslı KARAKILIÇ
Mehmet ATEŞ
Güven GÜVENDİ
Sevim KANDİŞ
Hikmet GÜMÜŞ
Servet KIZILDAĞ
Pages
257–262
Publication Date
2022-10-11
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

As a response to exercise, both the brain and serum oxytocin levels increased in female mice (both of p=0.0001); however, in males, oxytocin levels increased in only the brain (p

📌 3 Key Takeaways

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Objective & Hypothesis:Background: It is known that regular physical activity reduces anxiety.
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Key Findings & Data:Empathy is an important behavior in the living community; and also important for sportsmen during sportive competition and daily living life, because sportsmen are also role model of people.Aims: To investigate the effects of voluntary physical activity on oxytocin, anxiety, and empathy levels as well as the relationship between them.Study Design: Animal experiment.Methods: Male and female mice were made to exercise in running wheel cages for 6 weeks.
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Conclusion & Impact:As a response to exercise, both the brain and serum oxytocin levels increased in female mice (both of p=0.0001); however, in males, oxytocin levels increased in only the brain (p
🔬Design:Lab & Field Experiment
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background: It is known that regular physical activity reduces anxiety. Low anxiety levels affect mood, emotions, and empathy. Oxytocin is a powerful hormone that regulates social interaction, sexual reproduction, maternal–infant bonding, milk release, empathy, and anxiety. Empathy is an important behavior in the living community; and also important for sportsmen during sportive competition and daily living life, because sportsmen are also role model of people.Aims: To investigate the effects of voluntary physical activity on oxytocin, anxiety, and empathy levels as well as the relationship between them.Study Design: Animal experiment.Methods: Male and female mice were made to exercise in running wheel cages for 6 weeks. Their empathy and anxiety levels were evaluated by using Helping Behavior test and elevated plus maze and open field test, respectively. And then the brain and blood oxytocin levels were measured.Results: Empathy-like behavior was improved in both genders of the exercise groups (door-opening time decreased in both genders of exercise groups, p for both=0.0001). As a response to exercise, both the brain and serum oxytocin levels increased in female mice (both of p=0.0001); however, in males, oxytocin levels increased in only the brain (p

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Cite This Article

YÜKSEL, O., UYSAL, N., YÜCE, Z., KOÇ, B., KARAKILIÇ, A., ATEŞ, M., GÜVENDİ, G., KANDİŞ, S., GÜMÜŞ, H., KIZILDAĞ, S. (2022). Regular Aerobic Voluntary Exercise Increased Oxytocin in Female Mice: The Cause of Decreased Anxiety and Increased Empathy-Like Behaviors. Balkan Medical Journal, Cilt: 36 - Sayı: 5, 257–262. https://ajindex.com/articles/460968

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