Journals / Balkan Medical Journal / 2020 / Cilt: 37 - Sayı: 1

Pathological Yawning in Patients with Acute Middle Cerebral Artery Infarction: Prognostic Significance and Association with the Infarct Location

Pages
24–28
Publication Date
2022-10-11
DOI
—
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Insular and opercular infarctswere detected in 65 (40.4%) and 54 (33.5%) patients, respectively.Pathological yawning was more frequently observed in patientswith cortical, insular, and opercular infarcts (p

📌 3 Key Takeaways

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Objective & Hypothesis:Background: Pathological yawning is a compulsive, frequent,repetitive yawning triggered by a specific reason besides fatigue orboredom.
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Key Findings & Data:Moreover, it could also beseen in the course of an ischemic stroke.Aims: To determine whether pathological yawning is a prognosticmarker of middle cerebral artery stroke and evaluate its relationshipwith the infarct location.Study Design: Cross-sectional study.Methods: We examined 161 patients with acute middle cerebralartery stroke, consecutively admitted to emergency department.Demographic information, stroke risk factors, stroke type accordingto Trial of Org 10172 in Acute Stroke Treatment classification, bloodoxygen saturation, body temperature, blood pressure, heart rate,glucose levels, daytime of stroke onset, National Institutes of HealthStroke Scale score (National Institutes of Health Stroke Scale score, atadmission and 24 h), modified Rankin scale (at 3 months), and infarctlocations were documented.
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Conclusion & Impact:Insular and opercular infarctswere detected in 65 (40.4%) and 54 (33.5%) patients, respectively.Pathological yawning was more frequently observed in patientswith cortical, insular, and opercular infarcts (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background: Pathological yawning is a compulsive, frequent,repetitive yawning triggered by a specific reason besides fatigue orboredom. It may be related to iatrogenic, neurologic, psychiatric,gastrointestinal, or metabolic disorders. Moreover, it could also beseen in the course of an ischemic stroke.Aims: To determine whether pathological yawning is a prognosticmarker of middle cerebral artery stroke and evaluate its relationshipwith the infarct location.Study Design: Cross-sectional study.Methods: We examined 161 patients with acute middle cerebralartery stroke, consecutively admitted to emergency department.Demographic information, stroke risk factors, stroke type accordingto Trial of Org 10172 in Acute Stroke Treatment classification, bloodoxygen saturation, body temperature, blood pressure, heart rate,glucose levels, daytime of stroke onset, National Institutes of HealthStroke Scale score (National Institutes of Health Stroke Scale score, atadmission and 24 h), modified Rankin scale (at 3 months), and infarctlocations were documented. Pathological yawning was defined as≥3 yawns/15 min. All patients were observed for 6 hours to detectpathological yawning. National Institutes of Health Stroke Scale score>10 was determined as severe stroke. The correlation between thepresence of pathological yawning and stroke severity, infarct location,and the short- and long-term outcomes of the patients were evaluated.Results: Sixty-nine (42.9%) patients had pathological yawning and112 (69.6%) had cortical infarcts. Insular and opercular infarctswere detected in 65 (40.4%) and 54 (33.5%) patients, respectively.Pathological yawning was more frequently observed in patientswith cortical, insular, and opercular infarcts (p

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Cite This Article

GÜNDOĞDU, A. A., ÖZDEMİR, A. Ö., ÖZKAN, S. (2022). Pathological Yawning in Patients with Acute Middle Cerebral Artery Infarction: Prognostic Significance and Association with the Infarct Location. Balkan Medical Journal, Cilt: 37 - Sayı: 1, 24–28. https://ajindex.com/articles/460905

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References (21)

  1. Writing Group Members, Mozaffarian D, Benjamin EJ, Go AS, Arnett DK, Blaha MJ, et al. Executive Summary: Heart Disease and Stroke Statistics--2016 Update: A Report From the American Heart Association. Circulation 2016;26;133:447-54
  2. Wolfe CD. The impact of stroke. Br Med Bull 2000;56:275-86
  3. Tur BS, Gursel YK, Yavuzer G, Kucukdeveci A, Arasil T. Rehabilitation outcome of Turkish stroke patients: in a team approach setting. Int J Rehabil Res 2003;26:271-7
  4. Barbizet J. Yawning. J Neurol Neurosurg Psychiatry1958;21:203-9
  5. Guggisberg AG, Mathis J, Schnider A, Hess CW. Why do we yawn? The importance of evidence for specific yawn-induced effects. Neurosci Biobehav Rev 2011;35:1302-4
  6. Krestel H, Bassetti CL, Walusinski O. Yawning- Its anatomy, chemistry, role, and pathological considerations. Prog Neurobiol 2018;161:61-78
  7. Walusinski O. Pathological Yawning, Laughing and Crying. Front Neurol Neurosci 2018;41:40-9
  8. Collins GT, Eguibar JR. Neurophamacology of yawning. Front Neurol Neurosci 2010;28:90-106
  9. Cattaneo L, Cucurachi L, Chierici E, Pavesi G. Pathological yawning as a presenting symptom of brainstem ischaemia in two patients. J Neurol Neurosurg Psychiatry 2006;77:98-100
  10. Thompson SB. The dawn of the yawn: is yawning a warning? Linking neurological disorders. Med Hypotheses 2010;75:630-3
  11. Walusinski O. Yawning in diseases. Eur Neurol 2009;62:180-7
  12. Daquin G, Micallef J, Blin O. Yawning. Sleep Med Rev 2001;5:299-312
  13. Teive HAG, Munhoz RP, Camargo CHF, Walusinski O. Yawning in neurology: a review. Arq Neuropsiquiatria 2018;76:473-80
  14. Postert T, Pöhlau D, Meves S, Nastos I, Przuntek H. Pathological yawning as a symptom of multiple sclerosis. J Neurol 1996;243:300-1
  15. Gallup AC, Gallup GG Jr, Feo C. Yawning, sleep, and symptom relief in patients with multiple sclerosis. Sleep Med 2010;11:329-30
  16. Gallup AC, Eldakar OT. The thermoregulatory theory of yawning: what we know from over 5 years of research. Front Neurosci 2013;6:188
  17. Bauer G, Gerstenbrand F, Hengl W. Involuntary motor phenomena in the locked-in syndrome. J Neurol 1980;223:191-8
  18. Fletcher S, Cohen F, Borenstein F, I Regev, Vardi J. Yawning as a paroxysmal sign of diencephalic seizures. Arch Psychol Psychiatry Neurol 1982;43:45-54
  19. Jacome DE. Compulsive Yawning as Migraine Premonitory Symptom. Cephalalgia 2001;21:623-5
  20. Sandyk R. Excessive yawning and progressive supranuclear palsy. Int J Neurosci 1987;34:123-4
  21. Williams DR. The y