Journals / Bozok Tıp Dergisi / 2018 / Cilt: 8 - Sayı:

Effect of Obstructive Sleep Apne Syndrome on Cardiac and Vascular Diseases

OBSTRÜKTİF UYKU APNE SENDROMUNUN KALP VE DAMAR HASTALIKLARI ÜZERİNE ETKİSİ

Pages
92–95
Publication Date
2022-10-11
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Cardiovascular disease and OSAS prevalence are parallel in especially older age groups, which is a parameter that should not be overlooked in terms of perioperative risk profile.

📌 3 Key Takeaways

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Objective & Hypothesis:Obstructive sleep apnea syndrome (OSAS) is a pathology of upper respiratory tract obstruction during sleep with consequent recurrent hypopnea and apnea attacks.
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Key Findings & Data:Prevalence is estimated to be 3.1-7.5% in males worldwide, 2.1-4.5% in females and the prevalence of disease is higher in older age (65 years and over).
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Conclusion & Impact:Cardiovascular disease and OSAS prevalence are parallel in especially older age groups, which is a parameter that should not be overlooked in terms of perioperative risk profile.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Obstructive sleep apnea syndrome (OSAS) is a pathology of upper respiratory tract obstruction during sleep with consequent recurrent hypopnea and apnea attacks. Prevalence is estimated to be 3.1-7.5% in males worldwide, 2.1-4.5% in females and the prevalence of disease is higher in older age (65 years and over). Sympathetic nervous system activation, elevated oxidative stress and proinflammatory response, platelet activation, and endothelial dysfunction were occurred due to sleeplessness and hypoxemia. Atherosclerosis, malignant dysrhythmias and sudden cardiac death are fatal complications of this entire process. As implicated by many studies, OSAS is an independent risk factor for cardiovascular disease. Cardiovascular disease and OSAS prevalence are parallel in especially older age groups, which is a parameter that should not be overlooked in terms of perioperative risk profile.

Özet

Obstrüktif uyku apnesi sendromu (OUAS) uyku esnasında üst solunum yolu tıkanıklıkları sonucutekrarlayan hipopne ve apne nöbetleri ile seyreden bir patolojidir. Prevelansı dünya genelindeerkeklerde %3.1-7.5 aralığında, kadınlarda %2.1-4.5 aralığında olup ileri yaş döneminde (65 yaşve üstü) hastalık prevalansının arttığı tahmin edilmektedir. Meydana gelen uykusuzluk, hipoksemi nedeniyle sempatik sinir sistemi aktivasyonu, artmış oksidatif stres ve proinflamatuar cevap,platelet aktivasyonu ve endotel disfonksiyonu meydana gelir. Tüm bu süreç beraber hareket ederek ateroskleroz oluşumu, malign disritmi ve ani kardiyak ölüm gibi fatal komplikasyonlar ile sonuçlanır. Birçok çalışma ile gösterildiği üzere OUAS kalp ve damar hastalıkları açısından bağımsızbir risk faktörüdür. Özellikle ileri yaş gruplarında kalp ve damar hastalıkları ile OUAS prevelansıparalellik göstermekte, bu da peroperatif risk profili açısından gözden kaçırılmaması gereken birparametre olarak karşımıza çıkmaktadır.

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Cite This Article

ATILGAN, K., DEMİRDAŞ, E., ÇİÇEKÇİOĞLU, F. (2022). Effect of Obstructive Sleep Apne Syndrome on Cardiac and Vascular Diseases. Bozok Tıp Dergisi, Cilt: 8 - Sayı:, 92–95. https://ajindex.com/articles/460040

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References (16)

  1. Jennum P, Riha RL. Epidemiology of sleep apnoea/hypopnoea syndrome and sleep-disordered breathing. Eur Resp J 2009;33:907- 14
  2. Somers VK, White DP, Amin R, et al. Sleep Apnea and cardiovascular disease. An American Heart Association/American College of Cardiology Foundation Scientific Statement From the American Heart Association Council for High Blood Pressure Research Professional Education Committee, Council on Clinical Cardiology, Stroke Council, and Council on Cardiovascular Nursing Council. Circulation 2008;118:1080-111
  3. Demir AU. Obstrüktif uyku apne sendromu (OUAS) ve obezite. Hacettepe Tıp Dergisi 2007; 38:177-93
  4. Baguet JP, Barone-Rochette G, Levy P. Left ventricular diastolic dysfunction is linked to severity of obstructive sleep apnoea. Eur Resp J 2010;36:1323-9
  5. Gottlieb DJ, Yenokyan G, Newman AB, et al. Prospective study of obstructive sleep apnea and incident coronary heart disease and heart failure: the sleep heart health study. Circulation 2010;122:352-60
  6. Kohli P, Balachandran JS, Malhotra A. Obstructive sleep apnea and the risk for cardiovascular disease. Curr Atheroscler Rep 2011;13:138-46
  7. Kasai T, Bradley TD. Obstructive sleep apnea and heart failure: pathophysiologic and therapeutic implications. J Am Coll Cardiol 2011;57:119-27
  8. Lurie A. Metabolic disorders associated with obstructive sleep apnea in adults. Adv Cardiol 2011;46:67-138
  9. Sánchez-de-la-Torre M, Campos-Rodriguez F, Barbé F. Obstructive sleep apnoea and cardiovascular disease. Lancet Resp Med 2013;1:61-72
  10. Muller JE, Tofler GH, Stone PH. Circadian variation and triggers of onset of acute cardio-vascular disease. Circulation 1989; 79:733- 43
  11. Young T, Palta M, Dempsey J, et al. The occurrence of sleepdisordered breathing among middle-aged adults. N Engl J Med 1993; 328:1230-5
  12. Punjabi NM. The epidemiology of adult obstructive sleep Apnea Proc Am Thorac Soc 2008; 5:136-43
  13. Bixler EO, Vgontzas AN, Lin HM, et al. Prevalence of sleepdisordered breathing in women: effects of gender. Am J Respir Crit Care Med 2001; 163:608-13
  14. Bearpark H, Elliott L, Grunstein R, et al. Snoring and sleep apnea: a population study in Australian men. Am J Respir Crit Care Med 1995; 151:1459-65
  15. Duran J, Esnaola S, Rubio R, Iztueta A. Obstructive sleep apneahypopnea and related clinical features in a population-based sample of subjects aged 30 to 70 yr. Am J Respir Crit Care Med 2001; 163:685-9
  16. Ip MS, Lam B, Lauder IJ, et al. A community study