Journals / Anadolu Kliniği Tıp Bilimleri Dergisi / 2021 / Cilt: 26 - Sayı: 2

A Comparison of the Clinical and Laboratory Characteristics of Influenza A and B Infections in Children

Çocuklarda İnfluenza A ve B Enfeksiyonlarının Klinik ve Laboratuvar Özelliklerinin Karşılaştırılması

Pages
180–186
Publication Date
2021-05-29
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Our findings indicate that Influenza A and B infections are, in general, very similar in terms of symptoms.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: In this study, we aimed to compare the clinical and laboratory findings of Influenza A and Influenza B infections in children.
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Key Findings & Data:Methods: The study included 1826 pediatric patients (aged <16 years) who were di¬agnosed with Influenza A (n=1400) and B (n=426) infections between 1 October 2019 and 30 April 2020.
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Conclusion & Impact:Conclusion: Our findings indicate that Influenza A and B infections are, in general, very similar in terms of symptoms.
🔬Design:Research Article
📍Scope:2019 Verileri
⚙️Variables:Influenza A · influenza B · çocuklar

Abstract

Aim: In this study, we aimed to compare the clinical and laboratory findings of Influenza A and Influenza B infections in children. Methods: The study included 1826 pediatric patients (aged <16 years) who were di¬agnosed with Influenza A (n=1400) and B (n=426) infections between 1 October 2019 and 30 April 2020. The patients were also divided into age groups: the age groups of 0–2 years, 3–9 years, and 10–16 years. The characteristic clinical and laboratory findings were compared. Results: Influenza A infection was significantly more common in patients aged <2 years and was significantly less common in patients aged 3–9 years. Body temperature was significantly higher in all age groups with Influenza A infection than in children with Influenza B infection. While leukocy¬tosis and lymphopenia were significantly more common in the Influenza A group, leukopenia and neutropenia were significantly more common in the Influenza B group. While acute otitis media was more common in Influenza A infection, myositis was more common in Influenza B infection. No significant difference was found between the Influenza A and B groups in terms of hospitalization rates. Of all patients, 98.3% were treated with oseltamivir. Conclusion: Our findings indicate that Influenza A and B infections are, in general, very similar in terms of symptoms. However, Influenza A infection is more common in very young children. It progresses with higher fever and is more frequently associated with pharyngeal hy¬peremia and acute otitis media, while leukopenia, neutropenia, conjunctivitis, nasal discharge, and myositis were found to be more common in Influenza B infection.

Özet

Amaç: Bu çalışmada, çocuklarda İnfluenza A ve İnfluenza B enfeksiyonlarının klinik ve laboratuvar bulgularını karşılaştırmak amaçlanmıştır. Yöntem: Çalışma 1 Ekim 2019 ile 30 Nisan 2020 tarihleri arasında İnfluenza A (n=1400) ve B (n=426) enfeksiyonu tanısı almış 16 yaş altı 1826 çocuk hasta içerdi. Hastalar aynı zamanda yaş gruplarına ayrıldı: 0–2 (yıl) yaş grubu, 3–9 yaş grubu, ve 10–16 yaş grubu. Karakteristik klinik bulgu¬lar ve laboratuvar bulguları karşılaştırıldı. Bulgular: İnfluenza A enfeksiyonu <2 yaşındaki hastalarda anlamlı biçimde daha yaygın, 3–9 ya¬şındaki hastalarda anlamlı biçimde daha enderdi. Vücut sıcaklığı İnfluenza A enfeksiyonlu tüm yaş gruplarında İnfluenza B enfeksiyonlu çocuklara göre anlamlı biçimde daha yüksekti. İnfluenza A grubunda lökositoz ve lenfopeni anlamlı biçimde daha yaygınken, İnfluenza B grubunda lökopeni ve nötropeni anlamlı biçimde daha yaygındı. Akut orta kulak iltihabı İnfluenza A enfeksiyonunda daha yaygınken, miyozit İnfluenza B enfeksiyonunda daha yaygındı. Hastaneye yatış oranı açısından ise İnfluenza A ve B grupları arasında anlamlı fark bulunmadı. Tüm hastaların %98,3’ü oseltamivir ile tedavi edildi. Sonuç: Bulgularımız İnfluenza A ve B enfeksiyonlarının semptomlar açısından genel olarak çok benzer olduğuna işaret etmektedir. Bununla birlikte, İnfluenza A enfeksiyonu çok küçük çocuklarda daha yaygındır. Daha yüksek ateşle ilerler ve farengeal hiperemi ve akut orta kulak ilti¬habı daha sık görülür. Lökopeni, nötropeni, konjonktivit, burun akıntısı ve miyozitin ise İnfluenza B enfeksiyonunda daha yaygın olduğu tespit edilmiştir.

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Cite This Article

TEMEL, H., GUNDUZ, M., KOPRULU, G., KARAMAN, S., CELEBİ, M., DOGAN, M., TOSUN, A., OKUR, M. (2021). A Comparison of the Clinical and Laboratory Characteristics of Influenza A and B Infections in Children. Anadolu Kliniği Tıp Bilimleri Dergisi, Cilt: 26 - Sayı: 2, 180–186. https://ajindex.com/articles/459272

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References (9)

  1. Krammer F, Smith GJD, Fouchier RAM, Peiris M, Kedzierska K, Doherty PC, et al. Influenza. Nat Rev Dis Primers. 2018;4(1):3 Kondrich J, Rosenthal M. Influenza in children. Curr Opin Pediatr. 2017;29(3):297–302.
  2. Rotrosen ET, Neuzil KM. Influenza: a global perspective. Pediatr Clin North Am. 2017;64(4):911–36.
  3. Daley AJ, Nallusamy R, Isaacs D. Comparison of influ¬enza A and influenza B virus infection in hospitalized children. J Paediatr Child Health. 2000;36(4):332–5. Kumar V. Influenza in children. Indian J Pediatr. 2017;84(2):139–43.
  4. Mattila JM, Vuorinen T, Heikkinen T. Comparative se¬verity of influenza A and B infections in hospitalized children. Pediatr Infect Dis J. 2020;39(6):489–93. Dallman PR. In: Rudolph AM (ed.), Pediatrics, 16. ed. New York: Appleton-Century-Crofts; 1977:1178. Long SS, Vodzak J. Laboratory Manifestations of Infec¬tious Diseases, Principles and Practice of Pediatric Infec¬tious Diseases. Amsterdam: Elsevier; 2018:1447–59. Machado CM, de Souza ACMF, Romano CM, Freire WDS, Costa AA, Figueiredo WM, et al. Influenza A and B in a cohort of outpatient children and adolescent with influenza like-illness during two consecutive influenza seasons. Braz J Infect Dis. 2020;24(1):73–80.
  5. Tran D, Vaudry W, Moore D, Bettinger JA, Halperin SA, Scheifele DW, et al. Hospitalization for influenza A ver¬sus B. Pediatrics. 2016;138(3):e20154643. Hong KW, Cheong HJ, Song JY, Noh JY, Yang TU, Kim WJ. Clinical manifestations of influenza A and B in chil¬dren and adults at a tertiary hospital in Korea during the 2011–2012 season. Jpn J Infect Dis. 2015;68(1):20–6.
  6. Mancinelli L, Onori M, Concato C, Sorge R, Chiavelli S, Coltella L, et al. Clinical features of children hospitalized with influenza A and B infections during the 2012–2013 influenza season in Italy. BMC Infect Dis. 2016;16:6. Peltola V, Ziegler T, Ruuskanen O. Influenza A and B virus infections in children. Clin Infect Dis. 2003;36(3):299–305.
  7. Zhong PP, Zhang HL, Chen XF, Liang TF, Lin L, Yang SY, et al. [Lower respiratory tract infection caused by influ¬enza virus A and influenza virus B in Wenzhou, China: a clinical analysis of 366 children]. Zhongguo Dang Dai Er Ke Za Zhi. 2016;18(2):117–22.
  8. Esposito S, Principi N. Oseltamivir for influenza infec¬tion in children: risks and benefits. Expert Rev Respir Med. 2016;10(1):79–87.
  9. Szenborn L, Toczek-Kubicka K, Zaryczański J, Marchew¬ka-Kowalik M, Miśkiewicz K, Kuchar E. Benign acute childhood myositis during influenza B outbreak. Adv Exp Med Biol. 20