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Journals / Bağcılar Tıp Bülteni / 2020 / Cilt: 5 - Sayı: 4

C-reactive Protein to Albumin Ratio as aPrognostic Predictor in Larynx Cancer

Larinks Kanserinde Prognostik Bir Belirteç Olarak C-reaktif Protein Albümin Oranı

Şahin ÖĞREDEN
Mehmet Faruk OKTAY
Hasan Deniz TANSUKER
Abdurrahman Buğra CENGİZ
Bekir Can GÜMÜŞLÜ
Serkan KAYABAŞI
Pages
179–184
Publication Date
2022-10-12
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The 5ySrates of patients with a high CAR were worse than those in the low group(79.2% vs 73.2% p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: During the past decade, several inflammation-basedprognostic systems have been reported in the field of clinical oncology.Recently, C-reactive protein and albumin ratio (CAR) have showedtheir impact on a large variety of tumor types.
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Key Findings & Data:The aim of this study isto evaluate the impact CAR on prognosis and 5-year survival (5yS) inpatients operated for larynx cancer.
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Conclusion & Impact:The 5ySrates of patients with a high CAR were worse than those in the low group(79.2% vs 73.2% p
🔬Design:Research Article
📍Scope:2015 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: During the past decade, several inflammation-basedprognostic systems have been reported in the field of clinical oncology.Recently, C-reactive protein and albumin ratio (CAR) have showedtheir impact on a large variety of tumor types. The aim of this study isto evaluate the impact CAR on prognosis and 5-year survival (5yS) inpatients operated for larynx cancer. Method: One hundred eighteen patients operated in our center between2010 and 2015 were eligible for retrospective analysis. We evaluated theimpact of the CAR and neutrophil to lymphocyte ratio (NLR) on the 5yS.Univariate and multivariate Cox regression analyses were performed todetermine the associations of CAR.Results: The optimal cut-off level of CAR was at 0.993. A low and highCAR was assigned to 40.7% and 59.3% of patients, respectively. The 5ySrates of patients with a high CAR were worse than those in the low group(79.2% vs 73.2% p

Özet

Amaç: Geçtiğimiz on yıl boyunca, klinik onkoloji alanında enflamasyontemelli birkaç prognostik sistem bildirilmiştir. Son zamanlarda, C-reaktifprotein ve albümin oranı (CAO), çok çeşitli tümör tipleri üzerindeprognostik belirteç olarak kendini göstermiştir. Bu çalışmanın amacı,larinks kanseri nedeniyle opere edilen hastalarda CAO’nun prognoz ve 5yıllık sağkalım üzerine etkisini değerlendirmektir. Yöntem: 2010-2015 yılları arasında merkezimizde ameliyat edilen 118hasta retrospektif analiz için uygun bulunmuştur. CAO ve nötrofil lenfositoranın (NLO) 5 yıllık sağkalım üzerindeki etkisi değerlendirildi. CAO ilesağkalım ve prognoz arasındaki ilişkileri belirlemek için tek değişkenli veçok değişkenli Cox regresyon analizi yapıldı. Bulgular: CAO’nun optimal cut-off seviyesi 0,993 olarak hesaplandı.Hastaların sırasıyla %40,7 ve %59,3’ünde düşük ve yüksek CAO saptandı.Yüksek CAO’lu hastaların 5 yıllık sağkalım oranları düşük gruptakileregöre daha kötü idi (%79,2’ye karşı %73,2, p

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Cite This Article

ÖĞREDEN, Ş., OKTAY, M. F., TANSUKER, H. D., CENGİZ, A. B., GÜMÜŞLÜ, B. C., KAYABAŞI, S. (2022). C-reactive Protein to Albumin Ratio as aPrognostic Predictor in Larynx Cancer. Bağcılar Tıp Bülteni, Cilt: 5 - Sayı: 4, 179–184. https://ajindex.com/articles/458971

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