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Journals / Bağcılar Tıp Bülteni / 2020 / Cilt: 5 - Sayı: 3

Predictive Role of Monocyte to High-density Lipoprotein Ratio for Plaque Morphology in Asymptomatic Intermediate Carotid Stenosis

Asemptomatik Orta Düzey Karotis Darlığında Plak Morfolojisi için Monosit/Yüksek Yoğunluklu Lipoprotein Kolesterol Oranının Öngörücü Rolü

Erdem KARAÇÖP
Asım ENHOŞ
Pages
75–81
Publication Date
2022-10-12
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results: MHR was significantly higher in the mixed and fatty plaque groups (16.951±5.935 vs 20.181±9.405 vs 11.200±4.126, p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Carotid plaques are divided into calcified, mixed and fatty types according to the morphological ultrastructure.
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Key Findings & Data:Increased risk of rupture, thromboembolism and stroke are more pronounced in mixed and fatty carotid plaques due to composition and instability.
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Conclusion & Impact:Results: MHR was significantly higher in the mixed and fatty plaque groups (16.951±5.935 vs 20.181±9.405 vs 11.200±4.126, p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Carotid plaques are divided into calcified, mixed and fatty types according to the morphological ultrastructure. Increased risk of rupture, thromboembolism and stroke are more pronounced in mixed and fatty carotid plaques due to composition and instability. The present study aimed to assess the role of monocyte to high-density lipoprotein cholesterol (HDL-C) ratio (MHR) to predict mixed and fatty plaques in patients with intermediate carotid artery stenosis. Method: A total of 223 asymptomatic patients who had 50-70% stenosis in the carotid artery were included in this retrospective cohort study. Patients were assigned into three groups based on plaque morphology: 94 with calcified, 71 with mixed and 58 with fatty plaques. Groups were compared in terms of MHR. Predictive role of MHR for mixed and fatty plaque was investigated. Results: MHR was significantly higher in the mixed and fatty plaque groups (16.951±5.935 vs 20.181±9.405 vs 11.200±4.126, p

Özet

Amaç: Karotis plakları morfolojik alt yapıya göre kalsifik, mikst ve yağlıtiplere ayrılır. Mikst ve yağlı karotis plaklarının bileşimi ve kararsızlığınedeniyle artmış rüptür, tromboembolizm ve inme riski daha belirgindir.Bu çalışma, orta düzey karotis arter darlığı olan hastalarda monosit/ yüksek yoğunluklu lipoprotein kolesterol (HDL-C) oranının (MHR) mikstve yağlı plakları öngörmedeki rolünü değerlendirmeyi amaçlamıştır. Yöntem: Bu retrospektif kohort çalışmaya karotis arterde %50-70 stenozuolan toplam 223 asemptomatik hasta alındı. Hastalar plak morfolojisinegöre üç gruba ayrıldı: 94 kalsifik, 71 mikst ve 58 yağlı plak olanlar. GruplarMHR açısından karşılaştırıldı. MHR’nin mikst ve yağlı plak için öngörücürolü araştırıldı. Bulgular: Mikst ve yağlı plak grubunda MHR anlamlı olarak dahayüksekti (16,951±5,935’e karşı 20,181±9,405’e karşı 11,200±4,126, p

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Cite This Article

KARAÇÖP, E., ENHOŞ, A. (2022). Predictive Role of Monocyte to High-density Lipoprotein Ratio for Plaque Morphology in Asymptomatic Intermediate Carotid Stenosis. Bağcılar Tıp Bülteni, Cilt: 5 - Sayı: 3, 75–81. https://ajindex.com/articles/458967

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