Journals / Bağcılar Tıp Bülteni / 2021 / Cilt: 6 - Sayı: 4

Association Between Bifurcation Angle and Coronary No-reflow Following Primary Percutaneous Coronary Intervention in Patients

Primer Perkutan Koroner Girişim Sonrası Hastalarda Bifurkasyon Açısı ile Koroner No-reflow Arasındaki İlişki

Pages
361–369
Publication Date
2022-10-12
DOI
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⚡ TL;DR(Too Long; Didn't Read)

In addition, serum C-reactive protein levels were higher in patients with no-reflow compared to patients with normal flow (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Percutaneous coronary intervention (PCI) has become the treatment method for patients presenting with ST elevation myocardial infarction (STEMI).
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Key Findings & Data:Studies demonstrated a relationship between endothelial dysfunction and disturbed vascular flow due to angulation of vascular tree.
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Conclusion & Impact:In addition, serum C-reactive protein levels were higher in patients with no-reflow compared to patients with normal flow (p
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Percutaneous coronary intervention (PCI) has become the treatment method for patients presenting with ST elevation myocardial infarction (STEMI). One of the well-known complications of PCI is no-reflow. Studies demonstrated a relationship between endothelial dysfunction and disturbed vascular flow due to angulation of vascular tree. Although the relationship between hemodynamic alterations and coronary angulation is evident, there is a lack of detailed analysis in terms of hemodynamic changes between vascular geometry and coronary no-reflow. We aimed to elucidate the relationship between vascular geometry and coronary no-reflow. Method: We reviewed PCI database of our hospital and enrolled a total of 120 patients with STEMI, who developed no-reflow following PCI, and sex and age matched 80 patients with normal flow. For each group, demographic and clinical characteristics, laboratory values and two dimensional quantitative coronary angiography measurements were evaluated. Results: Patients with no-reflow had a higher prevalence of hypertension and diabetes mellitus. In addition, serum C-reactive protein levels were higher in patients with no-reflow compared to patients with normal flow (p

Özet

Amaç: Perkutan koroner girişim (PKG), ST yükselmeli miyokard enfarktüsü (STYMI) ile başvuran hastalarda tedavi yöntemidir. PKG’nin en iyi bilinen komplikasyonlarından biri, no-reflow’dur. Çalışmalar, endotel disfonksiyonu ile vasküler yapı angulasyonu nedeniyle bozulmuş vasküler akış arasındaki ilişkiyi göstermiştir. Hemodinamik değişiklikler ile koroner açılanma arasındaki ilişki hakkında bilgimiz olsa da, vasküler geometri ile koroner akım arasındaki hemodinamik değişiklikler açısından ayrıntılı bir analiz eksikliği vardır. Vasküler geometri ile koronerde no-reflow arasındaki ilişkiyi aydınlatmayı amaçladık. Yöntem: Hastanemizin PKG veri tabanını gözden geçirdik ve PKG’yi takiben no-reflow gelişen ve buna ek olarak cinsiyet ve yaşı eşleşen 80 normal akım olan hastayı 120 STYMI hastasını kaydettik. Her grup için demografik ve klinik özellikler, laboratuvar değerleri ve iki boyutlu kantitatif koroner anjiyografi ölçümleri değerlendirildi. Bulgular: No-reflow hastalarda daha yüksek hipertansiyon ve diabetes mellitus prevalansı vardı. Ek olarak, serum C-reaktif protein seviyeleri, normal akışa sahip hastalara kıyasla no-reflow gelişen hastalarda daha yüksekti (p

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Cite This Article

ŞAHİN, A. A., ERTÜRK, M., DURAN, M., TAŞBULAK, Ö., DEMİR, A. R., GÜLMEZ, R. (2022). Association Between Bifurcation Angle and Coronary No-reflow Following Primary Percutaneous Coronary Intervention in Patients. Bağcılar Tıp Bülteni, Cilt: 6 - Sayı: 4, 361–369. https://ajindex.com/articles/458952

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