Journals / Bağcılar Tıp Bülteni / 2021 / Cilt: 6 - Sayı: 3

The Performance Analysis of the Thyroid Nodule Size to Predict the Coexistence of Micropapillary Carcinoma

Mikropapiller Karsinom Birlikteliğini Tahmin Etmekte; Tiroid Nodül Boyutu Performans Analizi

Pages
234–241
Publication Date
2022-10-12
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

However, the nodule size has the low performance to be a predictor for the coexistence of IMC in the thyroid gland.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Incidental micropapillary carcinoma (IMC) is the most common variant of thyroid malignancies.
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Key Findings & Data:Method: The data of 194 patients who underwent biopsy for fine-needle aspiration cytology and subsequent thyroidectomy in a research and training hospital between January 2017 and February 2020 were analyzed retrospectively.
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Conclusion & Impact:However, the nodule size has the low performance to be a predictor for the coexistence of IMC in the thyroid gland.
🔬Design:Research Article
📍Scope:2017 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: Incidental micropapillary carcinoma (IMC) is the most common variant of thyroid malignancies. There are unmet needs regarding the efficacy of nodule size in the prediction of the coexistence of IMC. We aimed to measure the effect of nodule size on the prediction of the coexistence of IMC. Method: The data of 194 patients who underwent biopsy for fine-needle aspiration cytology and subsequent thyroidectomy in a research and training hospital between January 2017 and February 2020 were analyzed retrospectively. The patients were divided into three groups according to the sizes of thyroid nodules as 0-10 mm, 11-20 mm, and >20 mm. Logistic regression analysis was performed. Results: The patients with nodule size between 0 mm and 10 mm mostly showed hypothyroidism (51.0% vs. 28.8% vs. 41.8%) while patients with size between 11 mm and 20 mm mostly had euthyroidism (44.2% vs. 45.1% vs. 41.8%, p=0.0175). Both malignancy (51.9% vs. 49.0% vs. 42.9%, p=0.544) and IMC (65.4% vs. 51.0% vs. 56.0%, p=0.32) were observed more likely in patients with moderate size (11-20 mm). We found the following variables to be predictors for the coexistence of IMC: absence of halo [odds ratio (OR): 4.50, 95% confidence interval (CI): 1.61-14.71, p=0.007], and interestingly decrease in vascularity [OR: 0.33, 95% CI: 0.12-0.87, p=0.030], and total thyroidectomy, [OR: 4.55, 95% CI: 2.30- 9.56, p2 cm), we reported more IMC inside the thyroid gland. However, the nodule size has the low performance to be a predictor for the coexistence of IMC in the thyroid gland.

Özet

Amaç: İnsidental mikropapiller karsinom (İMK), tiroid malignitelerinin en yaygın mikropapiller varyantıdır ve son on yılda insidansı artmaktadır. Tiroid bezinde İMK varlığını tahmin etmede nodül boyutunun etkinliğine ilişkin veriler yeterli değildir. Bu retrospektif çalışmada nodül boyutunun, İMK’lerin tiroid bezinde diğer lezyonlarla bir arada bulunmasının öngörülmesine etkisini araştırdık. Yöntem: Ocak 2017-Şubat 2020 tarihleri arasında ince iğne aspirasyon sitolojisi ve ardından tiroidektomi için biyopsi yapılan 194 hastanın verileri retrospektif olarak incelendi. Hastalar tiroid nodüllerinin boyutlarına göre 0-10 mm, 11-20 mm ve >20 mm olarak üç gruba ayrıldı. Bulgular: Nodül boyutu 0-10 mm arasında olan hastalarda en çok hipotiroidizm (%51,0, %28,8 ve %41,8) görülürken, boyutu 11-20 mm arasındaki hastalarda en çok ötiroidizm görüldü (%44,2, %45,1 ve %41,8, p=0,0175). Hem malignitenin (%51,9, %49,0 ve %42,9, p=0,544) hem de İMK’nin (%65,4, %51,0 ve %56,0, p=0,32), orta büyüklükte (11-20 mm) nodül boyutu olan hastalarda görülme olasılığı yüksekti. Aşağıdaki değişkenlerin İMK’nin görülmesini daha fazla etkilediğini bulduk: halo yokluğu [olasılık oranı (OO): 4,50, %95 güven aralığı (GA): 1,61-14,71, p=0,007], vasküleritede azalma [OO: 0,33, %95 GA: 0,12-0,87, p=0,030] ve total tiroidektomi [OO: 4,55, %95 GA: 2,30-9,56, p2 cm) birlikte tiroid bezi içinde daha fazla İMK’ye rastlanmıştır. Bununla birlikte, nodül boyutunun tiroid bezinde İMK bulunma riski için prediktif bir faktör olma potansiyeli düşüktür.

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Cite This Article

ERCAN, G., ALTINEL, Y., HACIM, N. A., ERÇETİN, C., AKBAŞ, A., TOKOÇİN, M., MERİÇ, S., AKTOKMAKYAN, T. V., ÜLGEN, Y., VELİMİROVİC, M. (2022). The Performance Analysis of the Thyroid Nodule Size to Predict the Coexistence of Micropapillary Carcinoma. Bağcılar Tıp Bülteni, Cilt: 6 - Sayı: 3, 234–241. https://ajindex.com/articles/458915

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