Journals / Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi / 2015 / Cilt: 25 - Sayı: 1

Biological importance of vitamin d and relationship between dentistry

Vitamin d'nin biyolojik önemi ve diş hekimliği ile olan ilişkisi

Pages
128–134
Publication Date
2022-10-10
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In thisreview the metabolism of vitamin D, its function, theeffects of vitamin D on systems, and relationshipbetween dentistry is going to be mentioned.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Vitamin D has an important effect on calciumand phosphorus homeostasis and it is indispensible forbone formation.
📊
Key Findings & Data:Moreover vit amin D regulates alot ofgenes involved in cell differentiation and cellproliferation through nuclear vitamin D receptor of itsactive form, 1 , 25 -dihydroksyvitamin D3.
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Conclusion & Impact:In thisreview the metabolism of vitamin D, its function, theeffects of vitamin D on systems, and relationshipbetween dentistry is going to be mentioned.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Vitamin D has an important effect on calciumand phosphorus homeostasis and it is indispensible forbone formation. Moreover vit amin D regulates alot ofgenes involved in cell differentiation and cellproliferation through nuclear vitamin D receptor of itsactive form, 1 , 25 -dihydroksyvitamin D3. Besides itsimportant effects, vitamin D contributes to theprevention of various cance rs such as colon cancer,prostate cancer, and breast cancer, autoimmunediseases such as multiple sclerosis and diabetes,allergic diseases, cardiovascular and infectiousdiseases. In many studies, vitamin D insufficiency thatis proved to be related with bisphosphonate relatedosteonecrosis of jaw and periodontal diseases. In thisreview the metabolism of vitamin D, its function, theeffects of vitamin D on systems, and relationshipbetween dentistry is going to be mentioned.

Özet

Vitamin D, kalsiyum ve fosfor hemostazıüzerinde önemli bir etkiye sahiptir ve kemik gelişimiiçin de vazgeçilmezdir. Ayrıca aktif form olan 1,25 -dihidroksivitamin D3ün nükleer vitamin D reseptörüaracılığı ile hücre diferansiyasyonu ve proliferasyonuile ilgili birçok geni regüle etmektedir. Vitamin Dnin buönemli etkilerinin yanında kolon kanseri, prostatkanseri, akciğer kanseri gibi birçok kanser tipinin,multiple skleroz ve diyabet gibi otoimmun hastalıkların,allerjik, kardiyovasküler ve enfeksiyon hastalıklarınönlenmesinde de önemli bir yeri vardır. Vitamin Dyetersizliğinin çenelerde görülen bifosfonata bağlıosteonekroz ve periodontal hastalıklarla bağlantılıolduğu yapılan çalışmalarla kanıtlanmıştır. Buderlemede vitamin Dnin metabolizması, fonksiyonu,sistemler üzerine olan etkileri ve diş hekimliği ile olanilişkisinden bahsedilecektir.

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Cite This Article

KESKİNRÜZĞAR, A., YANIK, S., ARAS, M. H., ÇETİNER, S. (2022). Biological importance of vitamin d and relationship between dentistry. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi, Cilt: 25 - Sayı: 1, 128–134. https://ajindex.com/articles/452129

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References (15)

  1. Jameson JL, Weetman AP. Tiroid bezi hastalıkları. In: Braunwald E, Fauci AS, Kasper DL, Hauser SL, Longo DL, Jameson JL. Harrison İç Hastalıkları Prensipleri. 15 ed. İstanbul; Çeviri editörü: Sağlıker Y: Nobel Matbaac ılık. 2004. p.2060- 75
  2. Atas A, Çakmak A, Soran M. D Vitamin Metabolizması ve Rikets Hastalığı. Bakırköy Tıp Derg 2008;4:1 - 7
  3. Ersöz B, Kalsiyum ve fosfor metabolizmasını düzenleyen hormonlar. In: Onat T, Emerk K, Sözmen EY. İnsan Biyokimyası. Ankara; 2002. p.467- 72
  4. Jones G. Metabolism and biomarkers of vitamin D. Scand J Clin Lab Invest Suppl 2012;243:7- 13
  5. Bordelon P, Ghetu MV and Langan RC. Recognition and management of vitamin D deficiency. Am Fam Physician 2009;80:841 -6
  6. Holick MF and Chen TC. Vitamin D deficiency: a worldwide problem with health consequences. Am J Clin Nutr 2008;87:1080- 6
  7. Holick MF. Vitamin D: importance in the prevention of cancers, type 1 diabetes, heart disease, and osteoporosis. Am J Clin Nutr 2004;79:362- 71
  8. Holick MF. Sunlight an d vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease. Am J Clin Nutr 2004; 8:1678- 88
  9. Hokugo A, Christensen R, Chung EM, Sung EC, Felsenfeld AL, Sayre JW, Garrett N, Adams JS, Nishimura I. Increased prevale nce of bisphosphonate - related osteonecrosis of the jaw with vitamin D deficiency in rats. J Bone Miner Res 2010;25:1337- 49
  10. Lehrer S, Montazem A, Ramanathan L, Pessin - Minsley M, Pfail J, Stock RG, Kogan R. Normal serum bone markers in bisphosphonate -induced osteonecrosis of the jaws. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008;106:389–91
  11. Ardine M, Donadio M. Could the long -term persistence of low serum calcium levels and high serum parathyroid hormone levels during bisphosphonate treatment predi spose metastatic breast cancer patients to undergo osteonecrosis of the jaw? Ann Oncol 2006;17:1336–7
  12. Brannon PM, Yetley EA, Bailey RL, Picciano MF. Overview of the conference "Vitamin D and Health in the 21st Century: an Update". Am J Clin Nutr 2008;88:483 -90
  13. Norman AW. From vitamin D to hormone D: fundamentals of the vitamin D endocrine system essential for good health. Am J Clin Nutr 2008;88:491 -9
  14. Shihadeh Y. Güneşe maruz kalma şekillerinin D vitamini üretimindeki rolü. Uzmanlık Tezi İ. Ü, İstanbul. 1998
  15. Rucker RB. Handbook of vitamins. 3 ed. New York; Marcel Dekker: 2001. p.616 16. Zempleni J. Handbook of vitamins. 4 ed. New York; CRC Press:2008. p.608. 17.