Journals / Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi / 2019 / Cilt: 29 - Sayı: 2

CURRENT APPROACHES FOR TOOTH AGENESIS: A REVIEW

DIŞ EKSIKLIĞINDE GÜNCEL YAKLAŞIMLAR: DERLEME

Pages
332–339
Publication Date
2022-10-10
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Functional changesseen in genes which play role in tooth agenesis arementioned that there may be a relationship with thedevelopment of cancer and tooth agenesis may be asignificant marker for cancer.

📌 3 Key Takeaways

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Objective & Hypothesis:Hypodontia is defined as the congenital deficiency ofone or more teeth and is one of the most commondental anomalies in humans.
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Key Findings & Data:Multifactorial etiology caninclude environmental factors as well, since acombination of environmental and genetic factorsmight contribute to the occurrence of dental agenesis.Patient with missing teeth; reduced masticatoryability, inarticulate pronunciation may encounteresthetics and periodontal problems.
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Conclusion & Impact:Functional changesseen in genes which play role in tooth agenesis arementioned that there may be a relationship with thedevelopment of cancer and tooth agenesis may be asignificant marker for cancer.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Hypodontia is defined as the congenital deficiency ofone or more teeth and is one of the most commondental anomalies in humans. Multifactorial etiology caninclude environmental factors as well, since acombination of environmental and genetic factorsmight contribute to the occurrence of dental agenesis.Patient with missing teeth; reduced masticatoryability, inarticulate pronunciation may encounteresthetics and periodontal problems. Tooth agenesisdefinition, etiology, genes that cause tooth agenesisand treatment of tooth agenesis is mentioned in thisreview. Nowadays, many genes which play role intooth development reported to be a potentialcandidate gene in tooth agenesis. Functional changesseen in genes which play role in tooth agenesis arementioned that there may be a relationship with thedevelopment of cancer and tooth agenesis may be asignificant marker for cancer.

Özet

Hipodonti, bir veya daha fazla dişin konjenital eksikliği olarak tanımlanır ve insanlarda en sık görülen dental anomalilerden biridir. Genetik faktörlerin yanısıra çevresel faktörler veya bunların kombinasyonu diş eksikliklerinin görülmesine sebep olabilmektedir. Eksik dişlere sahip hastalar; azalmış çiğneme yeteneği, telaffuzun anlaşılamaması, estetik ve periodontal problemlerle karşılaşabilmektedir. Bu derlemede konjenital diş eksikliği tanımı, etiyolojisi, diş eksikliğine sebep olan genler ve tedavisinden bahsedilmektedir. Günümüzde, diş gelişiminde rol alan birçok genin, diş eksikliğinde de potansiyel aday genler oldukları bildirilmektedir. Diş eksikliğinde rol alan genlerde görülen fonksiyonel değişikliklerin kanser gelişimiyle bir ilişkisi olabileceğinden ve diş eksikliğinin kanser için belirleyici bir marker olabileceğinden bahsedilmektedir.

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Cite This Article

GÜZEL, K. G. U., ŞENTÜRK, Ö. (2022). CURRENT APPROACHES FOR TOOTH AGENESIS: A REVIEW. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi, Cilt: 29 - Sayı: 2, 332–339. https://ajindex.com/articles/451780

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References (11)

  1. Bailleul-Forestier I, Molla M, Verloes A, Berdal A. The genetic basis of inherited anomalies of the teeth. Part 1: clinical and molecular aspects of non-syndromic dental disorders. Eur J Med Genet 2008; 51: 273-91. Arte S. Phenotypic and genotypic features of familial hypodontia. Department of Pedodontics and Orthodontics Helsinki, Finland University of Helsinki 2001: 12-4.
  2. Polder BJ, Van't Hof MA, Van der Linden FP, Kuijpers-Jagtman AM. A meta-analysis of the prevalence of dental agenesis of permanent teeth. Community Dent Oral Epidemiol 2004; 32: 217-26.
  3. Shimizu T, Maeda T. Prevalence and genetic basis of tooth agenesis. Jpn Dentl Sci Rev 2009; 45: 52- 8. Nordgarden H, Jensen JL, Storhaug K. Reported prevalence of congenitally missing teeth in two Norwegian counties. Community Dent Health 2002; 19: 258-61. Fekonja A. Hypodontia in orthodontically treated children. Eur J Orthod 2005; 27: 457–60.
  4. Abed Al Jawad FH, Al Yafei H, Al Sheeb M, Al Emadi B, Al Hashimi N. Hypodontia prevalance and distribution pattern in a group of Qatari orthodontic and pediatric patients: A retrospective study. Eur J Dent 2015; 9: 267-71.
  5. Hashim HA, Al-Said S. The prevalance and distribution of hypodontia in a sample of Qatari patients. J Orthod Sci 2016; 5: 1-6.9. Hassan DA, Abuaffan AH, Hashim HA. Prevalence of hypodontia in a sample of Sudanese orthodontic patients. J Orthod Sci. 2014; 3: 63-7.
  6. Hassan DA, Abuaffan AH, Hashim HA. Prevalance of hypodontia in a sample of Sudanese orthodontic patients. J Orthod Sci 2014; 3: 63-7.
  7. Altuğ A, Erdem D. Prevalence and distribution of dental anomalies in orthodontic patients. Am J Orthod Dentofacial Orthop 2007; 131: 510-514.
  8. Aren G, Güven Y, Tolgay CG, Özcan İ, Bayar ÖF et al. The prevalence of dental anomalies in a Turkish population. J Istanbul Univ Fac Dent 2015; 49: 23- 8. Uslu O, Akcam MO, Evirgen S, Cebeci İ. Prevalence of dental anomalies in various malocclusions. Am J Orthod Dentofacial Orthop 2007; 135: 328-35.
  9. Celikoglu M, Kazanci F, Miloglu O, Oztek O, Kamak H, Ceylan I. Frequency and characteristics of tooth agenesis among an orthodontic patient population. Med Oral Patol Oral Cir Bucal 2010, 15: 797-801.
  10. Ezirganlı Ş, Köşger H, Özer K, Kırtay M, Ün E. Prevalence Of Congenİtally Missing Second Premolars. Cumhuriyet Dent J 2010, 13: 48-51.
  11. Kazanci F, Celikoglu M, Miloglu O, Ceylan I, Karmak H. Frequency and distribution of developmental anomalies in the permanent teeth of a Turkish orthodontic patient population. J Dent Sci 20