Journals / Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi / 2020 / Cilt: 30 - Sayı: 3

PROMISING BIOMARKERS IN THE DIAGNOSIS AND PROGNOSIS OF PERIODONTAL INFECTION

Periodontal Enfeksiyonun Teşhis ve Prognozunda Umut Vadeden Biyobelirteçler

Pages
499–506
Publication Date
2022-10-10
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, adipokines studied in various periodontal diseases are investigated and the applicability of adipokines as a biomarker in the field of periodontology is discussed.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Although periodontal disease is started by various bacteria, complex microflora and the host response affects periodontal condition and makes it difficult to identify specific disease marker.
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Key Findings & Data:Clinical parameters including such as bleeding on probing, probing depth, clinical attachment level and radiographic bone amount which used in the diagnosis of periodontal disease, are insufficient to evaluate the severity and prognosis of disease and response to treatment.
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Conclusion & Impact:In this review, adipokines studied in various periodontal diseases are investigated and the applicability of adipokines as a biomarker in the field of periodontology is discussed.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Although periodontal disease is started by various bacteria, complex microflora and the host response affects periodontal condition and makes it difficult to identify specific disease marker. Clinical parameters including such as bleeding on probing, probing depth, clinical attachment level and radiographic bone amount which used in the diagnosis of periodontal disease, are insufficient to evaluate the severity and prognosis of disease and response to treatment. Therefore, various biomarkers that can be detected in gingival fluid, saliva and serum sampels are the light of hope for us. Recently, some proteins, called adipokines, which have been released from adipocytes as tissue defense cells, have been reported. In this review, adipokines studied in various periodontal diseases are investigated and the applicability of adipokines as a biomarker in the field of periodontology is discussed.

Özet

Periodontal hastalıklar çeşitli mikroorganizmalar tarafından başlatılmış olsa da, kompleks mikroflorası ve konak yanıtı periodontaldurumu etkilemekte ve sipesifik hastalık belirteçlerini tanımlamayı zorlaştırmaktadır. Periodontal hastalık tanısında kullanılansondalamada kanama, cep derinliği, klinik ataçman seviyesi ve radyolojik kemik miktarı gibi klinik periodontal parametreler,hastalığın şiddetinin, prognozunun ve tedaviye verilen yanıtın değerlendirilmesinde yetersiz kalmaktadır. Bu nedenle, dişetioluğu sıvısı, tükürük ve serum öneklerinde tespit edilebilen çeşitli biyobelirteçler bu konuda bize umut ışığı olmaktadır. Sondönemlerde, doku savunma hücreleri olan adipositlerden salınan ve adipokinler olarak adlandırılan bazı proteinler raporedilmiştir. Bu derlemede, çeşitli periodontal hastalıklarda çalışılmış adipokinler incelenmiş ve gelecekte adipokinlerin birbiyobelirteç olarak periodontoloji alanında uygulanabilirliği tartışılmıştır.

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Cite This Article

ÇANAKÇI, C. F., ATA, Ö. Ş., ÖZKAN, Y. (2022). PROMISING BIOMARKERS IN THE DIAGNOSIS AND PROGNOSIS OF PERIODONTAL INFECTION. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi, Cilt: 30 - Sayı: 3, 499–506. https://ajindex.com/articles/451707

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