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Journals / Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi / 2021 / Cilt: 31 - Sayı: 3

EVALUATION OF THE ANTIMICROBIAL EFFICACY OF CHLORHEXIDINE, FLUCONAZOLE, LAURIC ACID AND COCONUT OIL ON CANDIDA SPECIES: AN IN VITRO STUDY

KLORHEKSİDİN, FLUKONAZOL, LAURİK ASİT VE HİNDİSTAN CEVİZİ YAĞININ KANDİDA TÜRLERİ ÜZERİNDEKİ ANTİMİKROBİYAL ETKİNLİĞİNİN DEĞERLENDİRİLMESİ: İN VİTRO ÇALIŞMA

Mehmet DEMİRCİ
Gülay ALTAN ŞALLI
Tamer Lütfi ERDEM
Özge ÜNLÜ
Edibe EGİL
Ahmet Bülent KATİBOĞLU
Özge ÖZDAL ZİNCİR
Pages
331–336
Publication Date
2022-10-10
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

For the significance level of the tests, p

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: This study aimed to investigate the in vitro antimicrobial efficacy of virgin coconut oil, and lauric acid on candida strains; to compare the activities of these agents with those of fluconazole, and chlorhexidine.
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Key Findings & Data:Candida strains; Candida albicans [American Type Culture Collection (ATCC)] 10231, C. tropicalis ATCC 750, C. krusei ATCC 6258 and C. glabrata ATCC 2001 standard strains were used.
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Conclusion & Impact:For the significance level of the tests, p
🔬Design:Research Article
📍Scope:2001 Verileri
⚙️Variables:Domain Parameters

Abstract

Aim: This study aimed to investigate the in vitro antimicrobial efficacy of virgin coconut oil, and lauric acid on candida strains; to compare the activities of these agents with those of fluconazole, and chlorhexidine. Material and methods: In our study, MIC (Minimum Inhibition Concentration) values on candida strains were determined using Chlorhexidine, Fluconazole, Lauric acid, and virgin coconut oil as antimicrobial agents. Candida strains; Candida albicans [American Type Culture Collection (ATCC)] 10231, C. tropicalis ATCC 750, C. krusei ATCC 6258 and C. glabrata ATCC 2001 standard strains were used. Candida strains were also diluted in BHI according to the 0.5 McFarland turbidity standard, and 10 µL was added to each well. Each plate was incubated at 37 ° C overnight. Candida growth in each well was measured at 600 nm optical density (OD) using an Epoch spectrophotometer (Biotek, Germany) according to the manufacturer's instructions. SPPS 25 (IBM Corp. Released 2017. IBM SPSS Statistics for Windows, Version 25.0. Armonk, NY: IBM Corp.) statistical package program was used to evaluate the data. For the significance level of the tests, p

Özet

Amaç: Bu çalışmanın amacı saf hindistan cevizi yağının ve laurik asitin kandida suşları üzerindeki in vitro antimikrobiyal etkinliğiniaraştırmak; bu ajanların aktivitelerini, flukonazol ve klorheksidin aktivitesiyle karşılaştırmaktır.Gereç ve yöntem: Çalışmamızda antimikrobiyal ajan olarak Klorheksidin, Flukonazol, Laurik asit, ve saf hindistan cevizi yağı kullanılarakkandida suşları üzerindeki MİK (Minimum İnhibisyon Konsantrasyonu) değerleri tespit edilmiştir. Kandida suşlarından; Candida albicans[American Type Culture Collection (ATCC)] 10231, C. tropicalis ATCC 750, C. krusei ATCC 6258 ve C. glabrata ATCC 2001 standartsuşları kullanılmıştır. Kandida suşları, 0.5 McFarland türbidite standardına göre BHI içerisinde de seyreltilmiş ve her kuyucuğa 10 uLeklenmiştir. Her plaka gece boyunca 37 ° C'de inkübe edilmiştir. Her oyuktaki kandida büyümesi, üretici talimatlarına göre Epochspektrofotometre (Biotek, Almanya) kullanılarak 600 nm optik yoğunlukta ölçülmüştür. Verilerin değerlendirilmesinde SPPS 25 (IBM Corp.Released 2017. IBM SPSS Statistics for Windows, Version 25.0. Armonk, NY: IBM Corp.) istatistik paket programı kullanılmıştır. Testlerinanlamlılık düzeyi için p

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Cite This Article

DEMİRCİ, M., ŞALLI, G. A., ERDEM, T. L., ÜNLÜ, Ö., EGİL, E., KATİBOĞLU, A. B., ZİNCİR, Ö. Ö. (2022). EVALUATION OF THE ANTIMICROBIAL EFFICACY OF CHLORHEXIDINE, FLUCONAZOLE, LAURIC ACID AND COCONUT OIL ON CANDIDA SPECIES: AN IN VITRO STUDY. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi, Cilt: 31 - Sayı: 3, 331–336. https://ajindex.com/articles/451566

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