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Journals / ARI The Bulletin of the Istanbul Technical University / 2003 / Cilt: 53 - Sayı: 1

Study of competitive protein-drug binding by capillary electrophoresis

Erim F.Bedia BERKER
Pages
65–69
Publication Date
2022-10-11
DOI
—
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⚡ TL;DR(Too Long; Didn't Read)

The binding constant between the displacer drug (furosemide) and BSA is estimated relative to the known warfarin-BSA binding constant.

📌 3 Key Takeaways

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Objective & Hypothesis:The competitive affinity of two drugs (the anticoagulant warfarin and the diuretic furosemide) to bovine serum albumin (BSA) is studied by capillary electrophoresis.
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Key Findings & Data:The competition of these two drugs for the same site on BSA is shown.
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Conclusion & Impact:The binding constant between the displacer drug (furosemide) and BSA is estimated relative to the known warfarin-BSA binding constant.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The competitive affinity of two drugs (the anticoagulant warfarin and the diuretic furosemide) to bovine serum albumin (BSA) is studied by capillary electrophoresis. The competition of these two drugs for the same site on BSA is shown. The binding constant between the displacer drug (furosemide) and BSA is estimated relative to the known warfarin-BSA binding constant.

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Cite This Article

BERKER, E. F. (2022). Study of competitive protein-drug binding by capillary electrophoresis. ARI The Bulletin of the Istanbul Technical University, Cilt: 53 - Sayı: 1, 65–69. https://ajindex.com/articles/448167

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References (1)

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