Results:Serum TNF-$alpha$ concentration was found significantly higher than the healthy controls in both groups (p
📌 3 Key Takeaways
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Objective & Hypothesis:Purpose:Mycobacterium tuberculosis and its components have been shown to stimulate mononuclear phagocytes in vitro to release interleukin-1beta (IL-1ß ), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-$alpha$).
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Key Findings & Data:Serum and BAL fluid levels of TNF-$alpha$ were determined in 32 patients with 19 active and 13 with inactive pulmonary TB.
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Conclusion & Impact:Results:Serum TNF-$alpha$ concentration was found significantly higher than the healthy controls in both groups (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Abstract
Purpose:Mycobacterium tuberculosis and its components have been shown to stimulate mononuclear phagocytes in vitro to release interleukin-1beta (IL-1ß ), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-$alpha$). TNF-$alpha$ levels both in serum and bronchoalveolar lavage (BAL) fluid were evaluated in active and inactive pulmonar tuberculosis (TB) as a diagnostic tool. Serum and BAL fluid levels of TNF-$alpha$ were determined in 32 patients with 19 active and 13 with inactive pulmonary TB. Methods:TNF-$alpha$ concentrations were measured by IMMULATE hormone autoanalyzer via chemiluminescent enzyme immunometric assay. Results:Serum TNF-$alpha$ concentration was found significantly higher than the healthy controls in both groups (p
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Cite This Article
YENİSEY, Ç., ERİŞ, F. N., SERTER, M. (2022). Serum and bronchoalveolar lavage (BAL) fluid tumor necrosis factor-alpha in active pulmonary tuberculosis. Annals of Medical Sciences, Cilt: 10 - Sayı: 2, 64–67. https://ajindex.com/articles/447456