The patient was diagnosed with hypokalemia likely due to Bartter's syndrome.
📌 3 Key Takeaways
🎯
Objective & Hypothesis:Biliary sludge has been reported to be associated with pregnancy, rapid weight loss, critical illness, prolonged fasting, long-term administration of total parenteral nutrition, ceftriaxone and octreotide therapy, and solid-organ and bone marrow transplantation.
📊
Key Findings & Data:Although biliary sludge accumulation is usually asymptomatic, it may lead to bile stone formation and various other complications.
💡
Conclusion & Impact:The patient was diagnosed with hypokalemia likely due to Bartter's syndrome.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Abstract
Biliary sludge has been reported to be associated with pregnancy, rapid weight loss, critical illness, prolonged fasting, long-term administration of total parenteral nutrition, ceftriaxone and octreotide therapy, and solid-organ and bone marrow transplantation. Although biliary sludge accumulation is usually asymptomatic, it may lead to bile stone formation and various other complications. It has not yet been proven that chronic hypokalemia causes, or predisposes patients to biliary sludge formation. We present the case of an adult male with acalculous gangrenous cholecystitis that was associated with biliary sludge. The patient was diagnosed with hypokalemia likely due to Bartter's syndrome.
🔖
Cite This Article
SERİN, E., BOYACIOĞLU, S., ÖZER, B., GÜMÜRDÜLÜ, Y. (2022). Biliary sludge associated with chronic hypokalemia in Bartter's syndrome. Annals of Medical Sciences, Cilt: 11 - Sayı: 2-3-4, 52–54. https://ajindex.com/articles/447426
Ko CW, Sekijima JH, Lee SP. Biliary sludge. Ann Intern Med 1999
Allen B, Bernhoft R, Blanckaert N, et al. Sludge is cal-cium bilirubinate associated with bile stasis. Am J Surg 1981
Park HZ, Lee SP, Schy AL. Ceftriaxone-associated gall-bladder sludge. Identification of calcium-ceftriaxone salt as a major component of gallbladder precipitate. Gastro-enterology 1991
Maringhini A, Marceno MP, Lanzarone F, et al. Sludge and stones after pregnancy. Prevalance and risk factors. J Hepatol 1987
Maringhini A, Ciambra M, Baccelliere P, et al. Biliarysludge and gallstones in pregnancy: incidence, risk fac-tors, and natural history. Ann Intern Med 1993
Shiffman ML, Sugerman HJ, Kellum JM,et al. Gallstone formation after rapid weight loss: a prospective study in patients undergoing gastric bypass surgery for treatment of morbid obesity. Am J Gastroenterol 1991
Murray FE, Stinchcombe SJ, Hawkey CJ. Development of biliary sludge in patients on intensive care unit: results of a prospective ultrasonographic study. Gut 1992
112 8.Bolondi L, Gaiani S, Testa S, et al. Gallbladder sludge formation during prolonged fasting after gastroinestinal tract surgery. Gut 1985
Pitt HA, King W 3d, Mann LL, et al. Increased risk of cholelithiasis with prolonged total parenteral nutrition. Am J Surg 1983
Goren A, Drachman R, Hadas-Halperin I, et al. Transient gallbladder dilatation associated with hypokalemia in a patient with Bartter’s syndrome. Eur J Pediatr 1989
Schaad UB, Tschappeler H, Lentze MJ. Transient forma-tion of precipitations in the gallbladder associated with ceftriaxone therapy. Pediatr Infect Dis 1986
Vance ML, Harris AG. Long-term treatment of 189 ac-romegalic patients with the somatostatin analog octreo-tide. Results of the International Multicenter AcromegalyStudy Group. Arch Intern Med 1991
Frick MP, Snover DC, Feinberg SB, et al. Sonography of the gallbladder in bone marrow transplant patients. Am J Gastroenterol 1984
Lorber MI, Van Buran CT, Flechner SM, et al. Hepato-biliary and pancreatic complications of cyclosporine ther-apy in 466 renal transplant recipients. Transplantation 1987
Lee SP, Maher K, Nicholis JF. Origin and fate of biliarysludge. Gastroenterology 1988
Ohara N, Schaefer J. Clinical significance of biliarysludge. J Clin Gastroenterol 1