The length of the gel aggregate of each sample which covers the pancreatic fluid in the tube was measured as mm and thereafter statistically compared.Results: Tisseel significantly formed an intensely thicker gel than Floseal and ABS (Tisseel vs FloSeal; P
📌 3 Key Takeaways
🎯
Objective & Hypothesis:Aim: Although recent developments in surgery led to mortality reduction under 2%, postoperative pancreatic fistula (POPF) remains high reported from 20% up to 40%.
📊
Key Findings & Data:Primary aim of the present in-vitro study was to determine the interaction between pancreatic fluid and three different hemostatic agents.Material and methods: Three different hemostatic agent; fibrin sealant Tisseel, Floseal and Ankaferd Blood Stopper (ABS) were mixed in tubes with pancreatic fluid in equal proportions.
💡
Conclusion & Impact:The length of the gel aggregate of each sample which covers the pancreatic fluid in the tube was measured as mm and thereafter statistically compared.Results: Tisseel significantly formed an intensely thicker gel than Floseal and ABS (Tisseel vs FloSeal; P
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Abstract
Aim: Although recent developments in surgery led to mortality reduction under 2%, postoperative pancreatic fistula (POPF) remains high reported from 20% up to 40%. Primary aim of the present in-vitro study was to determine the interaction between pancreatic fluid and three different hemostatic agents.Material and methods: Three different hemostatic agent; fibrin sealant Tisseel, Floseal and Ankaferd Blood Stopper (ABS) were mixed in tubes with pancreatic fluid in equal proportions. The length of the gel aggregate of each sample which covers the pancreatic fluid in the tube was measured as mm and thereafter statistically compared.Results: Tisseel significantly formed an intensely thicker gel than Floseal and ABS (Tisseel vs FloSeal; P
🔖
Cite This Article
ERCAN, M., AZİRET, M., BAL, A., KARAMAN, K., BOSTANCİ, E. B., OTER, V. (2022). Interaction between pancreatic fluid and three different hemostatic agents: An in-vitro study. Annals of Medical Research, Cilt: 26 - Sayı: 1, 47–50. https://ajindex.com/articles/447248
Bassi C, Dervenis C, Butturini G. et al; International Study Group on Pancreatic Fistula Definition. Postoperative pancreatic fistula: an international study group (ISGPF) definition. Surgery 2005;138: 8-13
Roberts KJ, Sutcliffe RP, Marudanayagam R, et al. Scoring System to Predict Pancreatic Fistula After Pancreaticoduodenectomy: A UK Multicenter Study. Ann Surg 2015;261:1191-7
Justin V, Fingerhut A, Khatkov I, et al. Laparoscopic pancreatic resection-a review. Transl Gastroenterol Hepatol 2016;1:36
Thaker RI, Matthews BD, Linehan DC, et al. Absorbable mesh reinforcement of a stapled pancreatic transection line reduces the leak rate with distal pancreatectomy. J Gastrointest Surg 2007;11:59-65
Kuroki T, Tajima Y, Tsuneoka N, et al. Gastric wall-covering method prevents pancreatic fistula after distal pancreatectomy. Hepatogastroenterol 2009;56:877-80
Walters DM, Stokes JB, Adams RB, et al. Use of a falciform ligament pedicle flap to decrease pancreatic fistula after distal pancreatectomy. Pancreas 2011;40:595 -9
Goh BK, Tan YM, Chung YF, et al. Critical appraisal of 232 consecutive distal pancreatectomies with emphasis on risk factors, outcome, and management of the postoperative pancreatic fistula: a 21-year experience at a single institution. Arch Surg 2008;143:956-65
Okabayashi T, Hanazaki K, Nishimori I, et al. Pancreatic transection using a sharp hook-shaped ultrasonically activated scalpel. Langenbecks. Arch Surg 2008;393:1005-8
Probst P, Hüttner FJ, Klaiber U, et al. Stapler versus scalpel resection followed by hand-sewn closure of the pancreatic remnant for distal pancreatectomy. Cochrane Database Syst Rev 2015;11:CD008688
Michalski CW, Tramelli P, Büchler MW, et al. Closure of pancreas stump after distal and segmental resection: Suture, stapler, coverage or anastomosis? Chirurg 2017;88:25-9
Fahy BN, Frey CF, Ho HS, et al. Morbidity, mortality, and technical factors of distal pancreatectomy. Am J Surg 2002;183:237-41
Liu QY, Zhang WZ, Xia HT, et al. Analysis of risk factors for postoperative pancreatic fistula following pancreaticoduodenectomy. World J Gastroenterol 2014;20:17491-7
Fu SJ, Shen SL, Li SQ, et al. Risk factors and outcomes of postoperative pancreatic fistula after pancreatico-duodenectomy: an audit of 532 consecutive cases. BMC Surg 2015;15:34
Sandini M, Malleo G, Gianotti L. Scores for Prediction of Fistula after Pancreatoduodenectomy: A Systematic Review. Dig Surg 2016;33: