AI Summary & Key Takeaways
AI InsightAlthough there was no statistically significant difference between the groups in terms of theamount of GCF/PISF periostin, periostin values were higher in peri-implant mucositis and gingivitis samples as compared to theperi-implantitis and periodontitis groups.Conclusion: Clinical parameters are a valid diagnostic tool for peri-implanter disease; there is a need for multicenter studies tounderstand the inflammatory basis of peri-implanter diseases that are biochemically prospective.
📌 3 Key Takeaways
Abstract
Aim: Periodontal and peri-implanter diseases are chronic, infectious and inflammatory diseases that manifest as a result of therelationship between their primary etiologic factor, i.e. microbial dental plaque, and the host defense system. Periostin is a proteinthat has been shown to play a functional role in wound repair, cardiovascular diseases, bone and tooth regeneration and toothmorphogenesis. In this study, the aim was to understand the role of periostin in periodontal (Gingivitis and Periodontitis) and periimplant (Peri-implant mucositis and Peri-implantitis) disease.Material and Methods: Forty-two subjects were enrolled in this cross-sectional study. In the clinical measurements, PPD, GI and PIvalues were measured from the implants and natural teeth. Peri-implant sulcus and gingival crevicular fluids were collected from thepatients using paper strips. Periostin levels were measured using ELISA. All parameter was statistically tested by using third partysoftware (SPSS v24.)Results: In terms of PPD, there was a statistically significant difference between the gingivitis-periodontitis, gingivitis-periimplantitis, peri-implant mucositis-periodontitis and peri-implant mucositis-peri-implantitis groups. There was a statisticallysignificant difference between the gingivitis-periodontitis, gingivitis-peri-implantitis and peri-implant mucositis-peri-implantitisgroups in terms of GCF/PISF volume. Although there was no statistically significant difference between the groups in terms of theamount of GCF/PISF periostin, periostin values were higher in peri-implant mucositis and gingivitis samples as compared to theperi-implantitis and periodontitis groups.Conclusion: Clinical parameters are a valid diagnostic tool for peri-implanter disease; there is a need for multicenter studies tounderstand the inflammatory basis of peri-implanter diseases that are biochemically prospective.