AI Summary & Key Takeaways
AI InsightAccording to regresion analysis,median nerve wrist segment sensory velocity and median nerve distal motor action potential amplitude were predictive parametersfor MUNE.Conclusion: Together with the clinical evaluation, patients with grade 3 and/or MUNE value below 2 standard deviations of normalaccording to the electrophysiological evaluation, should be considered for surgery, while in milder cases, it can be recommended thatclinical and electrophysiological follow-up is added to conservative treatment.
📌 3 Key Takeaways
Abstract
Aim: To determine the association of clinical and electrophysiological findings in cases of carpal tunnel syndrome (CTS) using motorunit (axon) number estimation (MUNE) of the median nerve and to evaluate how these findings can contribute to treatment planning.Material and Methods: Evaluation was made of 43 hands of 25 patients (22 females, 3 males, mean age 45.63±9.89 years) with clinicaland electrophysiological diagnosis proven CTS and a healthy control group of 50 hands of 25 subjects (21 females, 4 males, meanage 44.72±8.89 years). Electrophysiological nerve transmission measurements and CTS grading were applied. MUNE measurementwas made from the abductor pollicis brevis (APB) muscle with the incremental method.Results: According to the electrophysiological grading, the mean MUNE values were at Grade-0: 134.66±41.00, Grade-1: 78.83±33.51,Grade-2: 71.72±32.15 and Grade-3: 50.25±27.45. A positive correlation was determined between electrophysiological grading andAPB muscle atrophy, and median nerve latency. A negative correlation was determined with MUNE, muscle strength, median nerveamplitude and conduction velocity. Between MUNE and muscle strength, median nerve amplitude and conduction velocity there wasa positive correlation, between MUNE and median nerve latency, a negative correlation was found. According to regresion analysis,median nerve wrist segment sensory velocity and median nerve distal motor action potential amplitude were predictive parametersfor MUNE.Conclusion: Together with the clinical evaluation, patients with grade 3 and/or MUNE value below 2 standard deviations of normalaccording to the electrophysiological evaluation, should be considered for surgery, while in milder cases, it can be recommended thatclinical and electrophysiological follow-up is added to conservative treatment.