SavedAdd your journal

Journals / Annals of Medical Research / 2019 / Cilt: 26 - Sayı: 10

Lactose intolerance in the differential diagnosis of uneasy infants

Münevver Tuğba TEMEL
Levent TEMEL
Mehmet Enes COŞKUN
Abdullah Tuncay DEMİRYÜREK
Pages
2277–2280
Publication Date
2022-10-12
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The mean age of the patients was5.51±3.47 months (age range 1 to 18 months). 31% of the patients diagnosed with lactose intolerance were admitted to the hospitaldue to uneasiness and excessive crying, and all of the patients were previously diagnosed as having infantile colic.Conclusion: This study concludes that conducting tests for lactose intolerance might be beneficial in children that are presentedto the hospital due to unexplained crying after the fourth month, at which time there is an expectation of seeing an improvement incolic behavior.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: Intestinal lactase deficiency is the most common carbohydrate malabsorption and digestive disorder.
📊
Key Findings & Data:Uneasiness and excessive crying are frequently seen in the first 3 months oflife and constitute nearly 20% of the patients who are referred to a pediatrician.
💡
Conclusion & Impact:The mean age of the patients was5.51±3.47 months (age range 1 to 18 months). 31% of the patients diagnosed with lactose intolerance were admitted to the hospitaldue to uneasiness and excessive crying, and all of the patients were previously diagnosed as having infantile colic.Conclusion: This study concludes that conducting tests for lactose intolerance might be beneficial in children that are presentedto the hospital due to unexplained crying after the fourth month, at which time there is an expectation of seeing an improvement incolic behavior.
🔬Design:Review & Systematic Survey
📍Scope:2017 Verileri
⚙️Variables:Domain Parameters

Abstract

Aim: Intestinal lactase deficiency is the most common carbohydrate malabsorption and digestive disorder. If lactase deficiencycoexists with gastrointestinal symptoms such as abdominal distension, flatulence, abdominal pain, diarrhea, vomiting and nausea,then the term “lactose intolerance” is used clinically. Uneasiness and excessive crying are frequently seen in the first 3 months oflife and constitute nearly 20% of the patients who are referred to a pediatrician. This study aims to perform a retrospective analysisof the complaints of patients who have been diagnosed with lactose intolerance.Material and Methods: The files of patients, who were diagnosed with lactose intolerance between October 2017 and May 2018 inDefalife Hospital Pediatrics Outpatient Clinic, were retrospectively reviewed.Results: A total of 38 patients, consisting of 23 males and 15 females are included to the study. The mean age of the patients was5.51±3.47 months (age range 1 to 18 months). 31% of the patients diagnosed with lactose intolerance were admitted to the hospitaldue to uneasiness and excessive crying, and all of the patients were previously diagnosed as having infantile colic.Conclusion: This study concludes that conducting tests for lactose intolerance might be beneficial in children that are presentedto the hospital due to unexplained crying after the fourth month, at which time there is an expectation of seeing an improvement incolic behavior.

🔖

Cite This Article

TEMEL, M. T., TEMEL, L., COŞKUN, M. E., DEMİRYÜREK, A. T. (2022). Lactose intolerance in the differential diagnosis of uneasy infants. Annals of Medical Research, Cilt: 26 - Sayı: 10, 2277–2280. https://ajindex.com/articles/447002

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (17)

  1. Semenza G. Anchoring and biosynthesis of stalked brush border membrane proteins: glycosidases and peptidases of enterocytes and renal tubuli. Annu Rev Cell Biol 1986;2:255–13
  2. Heyman MB; Committee on Nutrition. Lactose intolerance in infants, children, and adolescents. Pediatrics 2006;118:1279-86
  3. Kim JS. Excessive crying: behavioral and emotional regulation disorder in infancy. Korean J Pediatr 2011; 54: 229-33
  4. Reijneveld SA, Brugman E, Hirasing RA. Excessive infant crying: the impact of varying definitions. Pediatrics 2001;108:893-97
  5. Barr RG, St. James-Roberts I, Keefe MR. New evidence on unexplained early infant crying: its origins, nature and management. Skillman, NJ: Johnson & Johnson Pediatric Institute, 2001
  6. Barr RG, Young SN, Wright JH, et al. Differential calming responses to sucrose taste in crying infants with and without colic. Pediatrics 1999;103:68
  7. Wahlqvist ML. Lactose nutrition in lactase nonpersisters. Asia Pac J ClinNutr 2015;24:21–25
  8. Harvey CB, Hollox EJ, Poulter M, et al. Lactase haplotype frequencies in Caucasians: association with the lactase persistence/non-persistence polymorphism. Ann Hum Genet 1998;62:215–23
  9. Itan Y, Jones BL, Ingram CJ, et al. A worldwide correlation of lactase persistence phenotype and genotypes. BMC Evol Biol 2010;10:36
  10. Lebenthal E, Antonowicz I, Shwachman H. Correlation of lactase activity, lactose tolerance and milk consumption in different age groups. Am J Clin Nutr 1975;28:595–600
  11. Welsh JD, Poley JR, Bhatia M, et al. Intestinal disaccharidase activities in relation to age, race, and mucosal damage. Gastroenterology 1978;75:847–55
  12. Woteki CE, Weser E, Young EA. Lactose malabsorption in Mexican-American children. Am J Clin Nutr 1976; 29:19–24
  13. Sahi T. Genetics and epidemiology of adulttype hypolactasia. Scand J Gastroenterol Suppl 1994;202:7–20
  14. Wang Y, Harvey CB, Hollox EJ, et al. The genetically pro- grammed down-regulation of lactase in children. Gastroenterology 1998;114:1230–36
  15. Antonowicz I, Lebenthal E. Developmental pattern of small intestinal enterokinase and disaccharidase activities in the human fetus. Gastroenterology 1977; 72:1299–1303
  16. Buller HA, Van Wassenaer AG, Raghavan S, et al. New insights into lactase and glycosylceramidase activities of rat lactase-phlorizin hydrolase. Am J Phys 1989;257:616–23
  17. Türkiye Nüfus ve Sağlık Araştırması (TNSA) (2013), Hacettepe Üniversitesi Nüfus Etütleri Enstitüsü, T.C. Kalkınma Bakanlığı ve TÜ