Journals / Annals of Medical Research / 2020 / Cilt: 27 - Sayı: 1

Clinicopathological analysis of seven breast hamartomas and review of the literature

Pages
271–276
Publication Date
2022-10-12
DOI
—
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In addition to these lesions, columnar cell hyperplasia was also identified.Malignancies are rarely detected in breast hamartomas; however, one case of ductal carcinoma in situ in a myoid hamartoma wasdetected.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Breast hamartomas are uncommon benign lesions that constitute 4.8% of benign breast tumors; they consist of mammaryducts and lobules, fatty tissue, and fibrous tissue.
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Key Findings & Data:The aim of this study was to determine the clinical and pathological characteristicsof breast hamartomas diagnosed by surgical resection and to examine the accompanying lesions.Material and Methods: Patients who underwent breast surgery between January 2013 and January 2018 at Konya Education andResearch Hospital and who were diagnosed as having breast hamartomas were reviewed retrospectively.Results: Seven breast hamartomas were identified.
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Conclusion & Impact:In addition to these lesions, columnar cell hyperplasia was also identified.Malignancies are rarely detected in breast hamartomas; however, one case of ductal carcinoma in situ in a myoid hamartoma wasdetected.
🔬Design:Review & Systematic Survey
📍Scope:2013 Verileri
⚙️Variables:Domain Parameters

Abstract

Aim: Breast hamartomas are uncommon benign lesions that constitute 4.8% of benign breast tumors; they consist of mammaryducts and lobules, fatty tissue, and fibrous tissue. The aim of this study was to determine the clinical and pathological characteristicsof breast hamartomas diagnosed by surgical resection and to examine the accompanying lesions.Material and Methods: Patients who underwent breast surgery between January 2013 and January 2018 at Konya Education andResearch Hospital and who were diagnosed as having breast hamartomas were reviewed retrospectively.Results: Seven breast hamartomas were identified. All of them were female. The mean age was 45 years. The mean tumor sizewas 3.9 cm. Most of the lesions were located in the right breast (57.1%). All the hamartomas appeared in the upper part of thebreast. Five of the seven cases were admitted with a painless palpable mass in the breast (71.4%). Three of the seven cases weremyoid hamartomas. The type of lesion most commonly associated with breast hamartomas is cyst formation. Pseudoangiomatousstromal hyperplasia, columnar cell hyperplasia, and ductal epithelial hyperplasia are also common. Ductal epithelial hyperplasia andcolumnar cell hyperplasia were observed in all the myoid hamartomas. Ductal carcinoma in situ was detected in one case; it wasalso a myoid hamartoma.Conclusions: Breast hamartomas are accompanied by many types of lesions such as fibrocystic changes, adenosis, ductal epithelialhyperplasia, and pseudoangiomatous stromal hyperplasia. In addition to these lesions, columnar cell hyperplasia was also identified.Malignancies are rarely detected in breast hamartomas; however, one case of ductal carcinoma in situ in a myoid hamartoma wasdetected.

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Cite This Article

KARANİS, M. İ. E., KÜÇÜKKOSMANOĞLU, İ., ALTUNKESER, A., KÖKSAL, H. (2022). Clinicopathological analysis of seven breast hamartomas and review of the literature. Annals of Medical Research, Cilt: 27 - Sayı: 1, 271–276. https://ajindex.com/articles/446844

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