Journals / Annals of Medical Research / 2019 / Cilt: 26 - Sayı: 7

The correlation between delirium subtypes and treatment efficacy and biochemical parameters: A preliminary study

Pages
1283–1288
Publication Date
2022-10-12
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Further studies are required to be conducted with bigger sampling groups.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Delirium is one of the most important emergency cases in geriatric patient population with high morbidity and mortality rates.In clinical practice, three delirium types are defined as hyperactive, hypoactive and mixed according to the psychomotor activity andthe level of wakefulness.
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Key Findings & Data:Following the classification of the patients according to the subtypes of delirium, they were evaluated before thetreatment and on the 7th day of the treatment.
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Conclusion & Impact:Further studies are required to be conducted with bigger sampling groups.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: Delirium is one of the most important emergency cases in geriatric patient population with high morbidity and mortality rates.In clinical practice, three delirium types are defined as hyperactive, hypoactive and mixed according to the psychomotor activity andthe level of wakefulness. In the present study, the purpose was to examine the treatment response of the subtypes of delirium andits relation with possible biochemical parameters.Material and Methods: Thirty patients, who were diagnosed with delirium and who were hospitalized for treatment were included inthe present study. Following the classification of the patients according to the subtypes of delirium, they were evaluated before thetreatment and on the 7th day of the treatment. In both interviews, the Delirium Rating Scale (DRS), Richmond Agitation and SedationScale (RASS), and Memorial Delirium Rating Scale (MDRS) were applied to the patients. In addition, the biochemical parameters thatwere required for the patients in relevant clinics were recorded.Results: Delirium patients consisted of a total of 30 patients. The patients of all three subtypes of delirium responded to the treatmentscores at significant levels in terms of scale scores. However, when the Hyperactive, Hypoactive and Mixed subtypes were evaluatedin terms of the difference of change on the 1st and 7th days of the treatment separately, it was determined that the difference ofchange values were significantly higher in the hyperactive type in terms of RASS, DRS and MDRS (p=0.004; p=0.002; p=0.001,respectively).Conclusions: As a result, the findings of the present study showed that patients who are diagnosed with delirium might show differenttreatment responses according to motor subtypes. Further studies are required to be conducted with bigger sampling groups.

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Cite This Article

GUROK, M. G., ATMACA, M., KAYA, M. O., KAZGAN, A. (2022). The correlation between delirium subtypes and treatment efficacy and biochemical parameters: A preliminary study. Annals of Medical Research, Cilt: 26 - Sayı: 7, 1283–1288. https://ajindex.com/articles/446823

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References (14)

  1. American psychiatric association. diagnostic and statistical manual of mental disorders: dsm-5. Arlington, VA: American Psychiatric Association, 2013;291-327
  2. Ely EW, Margolin R, Francis J, et al. Evaluation of delirium in critically ill patients: validation of the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU). Crit Care Med 2001;29:1370-9
  3. Witlox J, Eurelings LS, de Jonghe JF, et al. Delirium in elderly patients and the risk of postdischarge mortality, institutionalization, and dementia: a meta-analysis. JAMA 2010;304:443-51
  4. Morandi A, Davis D, Fick DM, et al. Delirium superimposed on dementia strongly predicts worse outcomes in older rehabilitation inpatients. J Am Med Dir Assoc 2014;15:349- 54
  5. Kyziridis TC. Post-operative delirium after hip fracture treatment: a review of the current literature. GMS Psycho- Social-Med 2006;3:1-12
  6. Mouzopoulos G, Vasiliadis G, Lasanianos N, et al. Fascia iliaca block prophylaxis for hip fracture patients at risk for delirium: a randomized placebo-controlled study. J Orthopaed Traumatol 2009;10:127-33
  7. Munster BC, Korse CM, Rooij SE, et al. Markers of cerebral damage during delirium in elderly patients with hip fracture. BMC Neurol 2009;9:21 8. Slor CJ, Adamis D, Jansen RW, et al. Delirium motor subtypes in elderly hip fracture patients: risk factors, outcomes and longitudinal stability. J Psychosom Res 2013;74:444-9
  8. Grover S, Sharma A, Aggarwal M, et al. Comparison of symptoms of delirium across various motoric subtypes. Psychiatry Clin Neurosci 2014;68:283-91
  9. Meagher DJ, Leonard M, Donnelly S, et al. A longitudinal study of motor subtypes in delirium: frequency and stability during episodes. J Psychosom Res 2012;72:236-41
  10. Heidrich, DE. Delirium: An Under-Recognized Problem. Clin J Oncol Nurs 2007;11:805-7
  11. Morandi A, Di Santo SG, Cherubini A, et al. Clinical Features Associated with Delirium Motor Subtypes in Older Inpatients: Results of a Multicenter Study. Am J Geriatr Psychiatry 2017;25:1064-71
  12. Kiely DK, Jones RN, Bergmann MA, et al. Association between psychomotor activity delirium subtypes and mortality among newly admitted post-acute facility patients. J Gerontol A Biol Sci Med Sci 2007;62:174-9
  13. Inouye SK, Viscoli CM, Horwitz RI, et al. A predictive model for delirium in hospitalized elderly medical patients based on admission characteristics. Ann Intern Med 1993;119:474- 81
  14. Inouye SK, Westendorp RG, Saczynski JS. Delirium in elderly peopl