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Journals / Annals of Medical Research / 2019 / Cilt: 26 - Sayı: 9

The effects of acrylamide and vitamin E administration during pregnancy on adults’ ovarian tissue: An experimental study

Mehmet Erman ERDEMLİ
Zeliha SELAMOGLU
Yusuf TÜRKOZ
Zeynep ERDEMLİ
Harika GÖZÜKARA BAG
Pages
1856–1860
Publication Date
2022-10-12
DOI
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It was determined that vitamin E administrationcaused an increase in GSH, SOD, CAT and TAS levels in ovarian tissues, compared to all other groups (P

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Objective & Hypothesis:Aim: The aim of the present study is to investigate the effects on ovarian tissues of adult female rats, which were the offspring ofrats administered acrylamide (AA) and vitamin E during pregnancy.Material and Methods: Thirty rats were divided into 5 groups of 6 pregnant rats, as the Control, Corn Oil, Vitamin E, AA, Vitamin E +AA groups.
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Key Findings & Data:The births were monitored on the 21st day to select the female rats.
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Conclusion & Impact:It was determined that vitamin E administrationcaused an increase in GSH, SOD, CAT and TAS levels in ovarian tissues, compared to all other groups (P
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: The aim of the present study is to investigate the effects on ovarian tissues of adult female rats, which were the offspring ofrats administered acrylamide (AA) and vitamin E during pregnancy.Material and Methods: Thirty rats were divided into 5 groups of 6 pregnant rats, as the Control, Corn Oil, Vitamin E, AA, Vitamin E +AA groups. The births were monitored on the 21st day to select the female rats. The selected female rats were decapitated at the endof the 8th week and their ovarian tissues were removed under anesthesia malondialdehyde (MDA), reduced glutathione (GSH), totalantioxidant capacity (TAS), total oxidant capacity (TOS), oxidative stress index (OSI), superoxide dismutase (SOD), catalase (CAT)and nitric oxide (NO) levels were examined.Results: Administration of AA during pregnancy caused an increase in MDA, TOS, OSI and NO levels and a decrease in GSH, SOD, CATand TAS levels in the ovarian tissues of the rats when compared to the control group. It was determined that vitamin E administrationcaused an increase in GSH, SOD, CAT and TAS levels in ovarian tissues, compared to all other groups (P

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Cite This Article

ERDEMLİ, M. E., SELAMOGLU, Z., TÜRKOZ, Y., ERDEMLİ, Z., BAG, H. G. (2022). The effects of acrylamide and vitamin E administration during pregnancy on adults’ ovarian tissue: An experimental study. Annals of Medical Research, Cilt: 26 - Sayı: 9, 1856–1860. https://ajindex.com/articles/446729

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