Journals / Annals of Medical Research / 2019 / Cilt: 26 - Sayı: 9

How should we approach thyroidal incidentalomas detected on FDG-PET/ CT imaging?

Pages
1997–2001
Publication Date
2022-10-12
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Therefore, TIs which detected byFDG-PET/CT should be examined pathologically due to high risk of malignancy.

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Objective & Hypothesis:Aim: Thyroidal incidentalomas (Tis) detected by F-18 fluorodeoxyglucose positron emission tomography/computed tomography(F-18FDG PET/CT) may be associated with three different causes that include metastasis of another malignancy, primary thyroidgland malignancies and lastly benign thyroidal nodules, all require different clinical approaches.
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Key Findings & Data:Forthese patients, histopathological results were accepted as definite diagnosis.Results: Malignant thyroidal pathologies were detected in 29.5% of patients.
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Conclusion & Impact:Therefore, TIs which detected byFDG-PET/CT should be examined pathologically due to high risk of malignancy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: Thyroidal incidentalomas (Tis) detected by F-18 fluorodeoxyglucose positron emission tomography/computed tomography(F-18FDG PET/CT) may be associated with three different causes that include metastasis of another malignancy, primary thyroidgland malignancies and lastly benign thyroidal nodules, all require different clinical approaches. For appropriate treatment, quickcharacterization of the Ti is important, preferably with a lesser invasive method. Our aim was to determine whether the characterizationof TIs can be performed with FDG-PET/CT, due to contribute faster diagnosis, and initiation of the therapy.Material and Methods: Forty-four patients with detected TIs in FDG-PET/CT were included in the study. The relationship betweenmetabolically/morphological parameters and pathology results were evaluated statistically. If two subsequent cytology werenegative, nodule accepted as benign. If cytology result was suspected or malignant, histopathological confirmation was made. Forthese patients, histopathological results were accepted as definite diagnosis.Results: Malignant thyroidal pathologies were detected in 29.5% of patients. We could not find any significant relationship betweenage, nodule size and SUVmax value and pathology results. According to ROC analysis, there were not any cut-off value for nodulesize and SUVmax. Similar results were also obtained for papillary carcinoma as a special subgroup.Conclusion: Characterisation of TIs could not be performed by using age, nodule size and SUVmax. Therefore, TIs which detected byFDG-PET/CT should be examined pathologically due to high risk of malignancy.

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Cite This Article

ÖZERCAN, İ. H., BALCI, T. A., UĞUR, K., NARİN, Y., KUŞLU, D., ŞİMŞEK, F. S., ARTAŞ, H., KOÇ, Z. P. (2022). How should we approach thyroidal incidentalomas detected on FDG-PET/ CT imaging?. Annals of Medical Research, Cilt: 26 - Sayı: 9, 1997–2001. https://ajindex.com/articles/446697

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