In conclusion well differentiated superficial invasive anal carcinomas (T1N0) can besuccessfully treated by local excision.
📌 3 Key Takeaways
🎯
Objective & Hypothesis:We present the treatment of squamous cell carcinoma (SCC) with anal margin localization on the basis of condyloma acuminata bylocal excision.
📊
Key Findings & Data:A 65-year-old male patient had complaints of bleeding, constipation and itching in the anal area.
💡
Conclusion & Impact:In conclusion well differentiated superficial invasive anal carcinomas (T1N0) can besuccessfully treated by local excision.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Abstract
We present the treatment of squamous cell carcinoma (SCC) with anal margin localization on the basis of condyloma acuminata bylocal excision. A 65-year-old male patient had complaints of bleeding, constipation and itching in the anal area. Physical examinationrevealed a 5x4 cm ulceration and an irregular mass in the anal margin localization. The incisional biopsy exposed a SCC thatdeveloped on the background of condyloma acuminata. Tumor was resected with ulcerated condyloma akumita and the skin defectwas successfully repaired with V-Y plasty. In conclusion well differentiated superficial invasive anal carcinomas (T1N0) can besuccessfully treated by local excision.
🔖
Cite This Article
YUR, M., LALE, A., AYGEN, E. (2022). Surgical treatment of squamous cell cancer with anal margin localization developed on the background of condyloma acuminata: A case report. Annals of Medical Research, Cilt: 27 - Sayı: 11, 3034–3036. https://ajindex.com/articles/446631
Scholefield J, Church J. Malignant tumors of the anal canal and anus. In: Keighley M, Williams N, eds. 3rd ed. Surgery of the Anus, Rectum and Colon. Philadelphia, PA: Saunders; 2007.p.567–90
Benson AB, Venook AP, Al-Hawary MM, et al. Anal Carcinoma, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw 2018;16:852-71. 3
Amin MB, Edge SB, Greene FL, et al, eds. AJCC Cancer Staging Manual. 8th ed. New York: Springer; 2017
Shiels MS, Kreimer AR, Coghill AE, et al. Anal Cancer Incidence in the United States, 1977-2011: Distinct patterns by histology and behavior. Cancer Epidemiol Biomarkers Prev 2015;24:1548-56
Nelson RA, Levine AM, Bernstein L, Smith DD, Lai LL. Changing patterns of anal canal carcinoma in the United States. J Clin Oncol 2013;31:1569-75
Uronis HE, Bendell JC. Anal cancer: an overview. Oncologist 2007;12:524-34
Centers for Disease Control and Prevention (CDC). Human papillomavirus-associated cancers - United States, 2004-2008. MMWR Morb Mortal Wkly Rep 2012;61:258-61
Altekruse SF, Kosary CL, Krapcho M, et al. SEER Cancer Statistics Review 2010;1975-2007
Cummings BJ. Metastatic anal cancer: the search for cure. Onkologie 2006;29:5-6
Goodman K, Rothenstein D, Lajhem C, et al. Capecitabine plus mitomycin in patients undergoing definitive chemoradiation for anal squamos cell carcinoma. Int. J Radiat Oncol Biol Phys 2014;90:32- 33 11. Hoots BE, Palefsky JM, Pimenta JM, et al. Human papillomavirus type distribution in anal cancer and anal intraepithelial lesions. Int J Cancer 2009;124:2375- 83
Palefsky JM, Giuliano AR, Goldstone S, et al. HPV vaccine against anal HPV infection and anal intraepithelial neoplasia. N Engl J Med 2011;365:1576- 85
Ajani JA, Winter KA, Gunderson LL, et al. Fluorouracil, mitomycin, and radiotherapy vs fluorouracil, cisplatin, and radiotherapy for carcinoma of the anal canal: a randomized controlled trial. JAMA 2008;299:1914-21
Chai CY, Tran Cao HS, Awad S, et al. Management of stage i squamous cell carcinoma of the anal canal. JAMA Surg 2018;153:209-15
Deshmukh AA, Zhao H, Das P, et al. Clinical and economic evaluation of treatment strategies for T1N0 anal canal cancer. Am J Clin Oncol 2018;41:626-31.