SavedAdd your journal

Journals / Annals of Medical Research / 2020 / Cilt: 27 - Sayı: 1

Can neutrophil-lymphocyte ratio be a predictor of lateonset sepsis in preterm infants?

Pelin DOĞAN
İpek GÜNEY VARAL
Pages
23–28
Publication Date
2022-10-12
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

NLR values were comparedwithin and between the groups.Results: Overall, final analysis were applied to 116 infants.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: Late-onset sepsis (LOS) persists to be a crucial reason of morbidity and mortality in preterm infants.
📊
Key Findings & Data:NLR values were comparedwithin and between the groups.Results: Overall, final analysis were applied to 116 infants.
💡
Conclusion & Impact:NLR values were raised in the study group during LOS episode (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: Late-onset sepsis (LOS) persists to be a crucial reason of morbidity and mortality in preterm infants. Studying the effect ofneutrophil-lymphocyte ratio (NLR) value in predicting the LOS episode and relation with the type of the growing microorganism werethe aim of this study.Material and Methods: Preterm infants were classified as two groups in accordance with having culture proven LOS during the stayin neonatal intensive care unit. Premature infants with culture proven LOS was defined as study group and infants with no-LOS ascontrol group. Study group is consisting of two subgroups in terms of the growing microorganism type. NLR values were comparedwithin and between the groups.Results: Overall, final analysis were applied to 116 infants. NLR values were raised in the study group during LOS episode (p

🔖

Cite This Article

DOĞAN, P., VARAL, İ. G. (2022). Can neutrophil-lymphocyte ratio be a predictor of lateonset sepsis in preterm infants?. Annals of Medical Research, Cilt: 27 - Sayı: 1, 23–28. https://ajindex.com/articles/446624

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (17)

  1. Bekhof J, Reitsma JB, Kok JH et al. Clinical signs to identify late-onset sepsis in preterm infants. Eur J Pediatr. 2013;172:501-8
  2. Satar M, Arisoy AE, Celik IH. Turkish Neonatal Society guideline on neonatal infections-diagnosis and treatment. Turk Pediatri Ars 2018;53(Suppl 1):88-100
  3. Dong Y, Speer CP. Late-onset neonatal sepsis: recent developments. Arch Dis Child Fetal Neonatal Ed 2015;100:F257-63
  4. Shane AL, Sanchez PJ, Stoll BJ. Neonatal sepsis. Lancet. 2017;390(10104):1770-80
  5. Pammi M, Weisman LE. Late-onset sepsis in preterm infants: update on strategies for therapy and prevention. Expert Rev Anti Infect Ther. 2015;13:487- 504
  6. Benitz WE. Adjunct laboratory tests in the diagnosis of early-onset neonatal sepsis. Clin Perinatol 2010;37:421-38
  7. Omran A, Maaroof A, Saleh MH, et al. Salivary C-reactive protein, mean platelet volume and neutrophil lymphocyte ratio as diagnostic markers for neonatal sepsis. J Pediatr (Rio J) 2018;94:82-7
  8. Can E, Hamilcikan S, Can C. The Value of Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio for Detecting Early-onset Neonatal Sepsis. J Pediatr Hematol Oncol 2018;40:e229-e32
  9. Temel MT, Coskun ME, Akbayram S, et al. Association between neutrophil/lymphocyte ratio with ductus arteriosus patency in preterm newborns. Bratisl Lek Listy 2017;118:491-4
  10. Kurtul BE, Kabatas EU, Zenciroglu A, et al. Serum neutrophil-to-lymphocyte ratio in retinopathy of prematurity. J AAPOS 2015;19:327-31
  11. Raimondi F, Ferrara T, Maffucci R, et al. Neonatal sepsis: a difficult diagnostic challenge. Clin Biochem 2011;44:463-4
  12. Paolucci M, Landini MP, Sambri V. How can the microbiologist help in diagnosing neonatal sepsis? Int J Pediatr 2012;2012:120139
  13. Chauhan N, Tiwari S, Jain U. Potential biomarkers for effective screening of neonatal sepsis infections: An overview. Microb Pathog 2017;107:234-42
  14. Mussap M, Noto A, Cibecchini F, et al. The importance of biomarkers in neonatology. Semin Fetal Neonatal Med 2013;18:56-64
  15. Liu X, Shen Y, Wang H, et al. Prognostic Significance of Neutrophil-to-Lymphocyte Ratio in Patients with Sepsis: A Prospective Observational Study. Mediators Inflamm 2016;2016:8191254
  16. Hwang SY, Shin TG, Jo IJ, et al. Neutrophil-tolymphocyte ratio as a prognostic marker in criticallyill septic patients. Am J Emerg Med 2017;35:234-9
  17. Ljungstrom L, Pernestig AK, Jacobsson G, et al. Diagnostic accuracy of procalcitonin, neutrophillymphocyte count ratio, C-reactive