Journals / Annals of Medical Research / 2020 / Cilt: 27 - Sayı: 6

Association between serum 25-hydroxyvitamin d and early recurrent ischemic stroke

Pages
1745–1750
Publication Date
2022-10-12
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Thesystolic blood pressure and diastolic blood pressures at the time of first consultation were higher in the recurrent ischemic strokegroup compared to the non-recurrent ischemic stroke group (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: Vitamin D deficiency has been reported as a new risk factor for ischemic stroke in recent years.
📊
Key Findings & Data:However, the pathophysiologicalmechanisms between recurrent ischemic stroke and decreased 25-hydroxyvitamin D [25(OH) D] are not clear.
💡
Conclusion & Impact:Thesystolic blood pressure and diastolic blood pressures at the time of first consultation were higher in the recurrent ischemic strokegroup compared to the non-recurrent ischemic stroke group (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: Vitamin D deficiency has been reported as a new risk factor for ischemic stroke in recent years. However, the pathophysiologicalmechanisms between recurrent ischemic stroke and decreased 25-hydroxyvitamin D [25(OH) D] are not clear. The aim of this studyis to examine the relationship between initial vitamin D levels and early recurrent stroke in patients presenting with acute ischemicstroke (AIS).Material and Methods: Four hundreds and ten consecutive patients who were followed-up with AIS diagnosis were included in thestudy. Risk factors for ischemic stroke were questioned and biochemical and cardiac examinations of the patients were performed.Simultaneously, the National Institutes of Health Stroke Scale (NIHSS) was calculated. Patients who had recurrent ischemic strokeobtained retrospectively were from the hospital registry system in last three month. The patients were divided into two groups asthose who had recurrent stroke and who did not.Results: A total of 410 patients, 187 of which were female (45.6%) and 223 of which were male (54.4%) with a mean age of 68.12 ±12.63 (29-99) were included in the study. Early recurrent ischemic stroke was detected in 48 (11.7%) patients in the follow-up. Thesystolic blood pressure and diastolic blood pressures at the time of first consultation were higher in the recurrent ischemic strokegroup compared to the non-recurrent ischemic stroke group (p

🔖

Cite This Article

ÖCEK, L., ÖCEK, Ö., MIZRAK, S. (2022). Association between serum 25-hydroxyvitamin d and early recurrent ischemic stroke. Annals of Medical Research, Cilt: 27 - Sayı: 6, 1745–1750. https://ajindex.com/articles/446614

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (16)

  1. Feigin VL, Forouzanfar MH, Krishnamurthi R, et al. Global and regional burden of stroke during 1990- 2010: findings from the Global Burden of Disease Study 2010. Lancet 2014;383:245-54
  2. Wang W, Jiang B, Sun H, et al. Prevalence, Incidence, and Mortality of Stroke in China: Results from a Nationwide Population-Based Survey of 480 687 Adults. Circulation 2017;135:759-71
  3. Zhang Q, Ding H, Yan J, et al. Plasma tissue kallikrein level is negatively associated with incident and recurrent stroke: a multicenter caseecontrol study in China. Ann Neurol 2011;70:265-73
  4. Wang A, Wu L, Wang X, et al. Effect of recurrent stroke on poor functional outcome in transient ischemic attack or minor stroke. Int J Stroke 2016;11:80-2
  5. Kojima G, Bell C, Abbott RD, et al. Low dietary vitamin D predicts 34-year incident stroke: The Honolulu Heart Program. Stroke 2012;43:2163-7
  6. Pilz, S, Dobnig H, Fischer JE, et al. Low vitamin d levels predict stroke in patients referred to coronary angiography. Stroke 2008;39:2611-3
  7. Buell JS, Dawson-Hughes B, Scott TM, et al. 25-Hydroxyvitamin D, dementia, and cerebrovascular pathology in elders receiving home services. Neurology 2010;74:18-26
  8. Bouillon R, Carmeliet G, Verlinden L, et al. Vitamin D and human health: Lessons from vitamin D receptor null mice. Endocr Rev 2008;29:726-76
  9. Guillot X, Semerano L, Saidenberg-Kermanac’h N, et al. Vitamin D and inflammation. Jt. Bone Spine 2010;77:552-7
  10. Brøndum-Jacobsen P, Nordestgaard BG, Schnohr P, et al
  11. Hydroxyvitamin D and symptomatic ischemic stroke: an original study and meta-analysis. Ann Neurol 2013;73:38-47
  12. Adams Jr HP, Bendixen BH, Kappelle LJ, et al. Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in acute stroke treatment. Stroke 1993;24:35-41
  13. Bamford J, Sandercock P, Dennis M, et al. Classification and natural history of clinically identifiable subtypes of cerebral infarction. Lancet 1991;337:1521-6
  14. Kilkkinen A, Knekt P, Aro A, et al. Vitamin D status and the risk of cardiovascular disease death. Am J Epidemiol 2009;170:1032-9
  15. Schierbeck LL, Rejnmark L, Tofteng CL, et al. Vitamin D deficiency in postmenopausal, healthy women predicts increased cardiovascular events: A 16-year follow-up study. Eur. J. Endocrinol 2012;167:553-60
  16. Alfieri DF, Lehmann MF, Oliveira SR, et al. Vitamin D deficiency is associated with acute ischemic stroke, C-reactive protein,